Extracellular vesicle-mediated amyloid transfer to neural progenitor cells: implications for RAGE and HIV infection

HIV-1 Tat-mediated microglial inflammation involves a novel miRNA-34a-NLRC5-NFκB signaling axis

(2019) Palsamy Periyasamy et al.   BRAIN BEHAVIOR AND IMMUNITY

Targeting the HIV-infected brain to improve ischemic stroke outcome

(2019) Luc Bertrand et al.   Nature Communications

Pediatric glioblastoma cells inhibit neurogenesis and promote astrogenesis, phenotypic transformation and migration of human neural progenitor cells within cocultures

(2018) Kurt Farrell et al.   EXPERIMENTAL CELL RESEARCH

Lower High-Density Lipoproteins Levels During Human Immunodeficiency Virus Type 1 Infection Are Associated With Increased Inflammatory Markers and Disease Progression

(2018) Damariz Marín-Palma et al.   Frontiers in Immunology

High-throughput identification of factors promoting neuronal differentiation of human neural progenitor cells in microscale 3D cell culture

(2018) Gregory J. Nierode et al.   BIOTECHNOLOGY AND BIOENGINEERING

Blood–brain barrier pericytes as a target for HIV-1 infection

(2018) Luc Bertrand et al.   BRAIN

Co-Localization of Glia Maturation Factor with NLRP3 Inflammasome and Autophagosome Markers in Human Alzheimer’s Disease Brain

(2017) Mohammad Ejaz Ahmed et al.   JOURNAL OF ALZHEIMERS DISEASE

Methamphetamine increases HIV infectivity in neural progenitor cells

(2017) Marta Skowronska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Potent NLRP3 Inflammasome Activation by the HIV Reverse Transcriptase Inhibitor Abacavir

(2017) Atiye Toksoy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Advanced glycation end products regulate anabolic and catabolic activities via NLRP3-inflammasome activation in human nucleus pulposus cells

(2017) Yu Song et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

HIV-1 Tat Primes and Activates Microglial NLRP3 Inflammasome-Mediated Neuroinflammation

(2017) Ernest T. Chivero et al.   JOURNAL OF NEUROSCIENCE

Extracellular vesicles of the blood-brain barrier: Role in the HIV-1 associated amyloid beta pathology

(2017) Ibolya E. András et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease

(2017) Carmen Venegas et al.   NATURE

Deletion of the Inflammasome Sensor Aim2 Mitigates Aβ Deposition and Microglial Activation but Increases Inflammatory Cytokine Expression in an Alzheimer Disease Mouse Model

(2017) Pei-Jung Wu et al.   NEUROIMMUNOMODULATION

Hippocampal adult neurogenesis: Its regulation and potential role in spatial learning and memory

(2016) Claudia Lieberwirth et al.   BRAIN RESEARCH

Inhibition of BCL-2 leads to increased apoptosis and delayed neuronal differentiation in human ReNcell VM cells in vitro

(2016) Michael Fröhlich et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

HIV-1 Viral Protein R Activates NLRP3 Inflammasome in Microglia: implications for HIV-1 Associated Neuroinflammation

(2016) Manmeet K. Mamik et al.   Journal of Neuroimmune Pharmacology

HMGB1 Induces Secretion of Matrix Vesicles by Macrophages to Enhance Ectopic Mineralization

(2016) Qiang Chen et al.   PLoS One

Characterization of Apoptosis Signaling Cascades During the Differentiation Process of Human Neural ReNcell VM Progenitor Cells In Vitro

(2015) Alexandra Jaeger et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Adult Neurogenesis in Neurodegenerative Diseases: Figure 1.

(2015) Beate Winner et al.   Cold Spring Harbor Perspectives in Biology

Cell-to-Cell Transmission of HIV-1 Is Required to Trigger Pyroptotic Death of Lymphoid-Tissue-Derived CD4 T Cells

(2015) Nicole L.K. Galloway et al.   Cell Reports

Transcriptional Profile of HIV-induced Nuclear Translocation of Amyloid β in Brain Endothelial Cells

(2014) Ibolya E. András et al.   ARCHIVES OF MEDICAL RESEARCH

HIV-1 stimulates nuclear entry of amyloid beta via dynamin dependent EEA1 and TGF-β/Smad signaling

(2014) Ibolya E. András et al.   EXPERIMENTAL CELL RESEARCH

A potential function for neuronal exosomes: Sequestering intracerebral amyloid-β peptide

(2014) Kohei Yuyama et al.   FEBS LETTERS

HIV-1 Infection Induces Interleukin-1β Production via TLR8 Protein-dependent and NLRP3 Inflammasome Mechanisms in Human Monocytes

(2014) Haitao Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decreased Amyloid-β Pathologies by Intracerebral Loading of Glycosphingolipid-enriched Exosomes in Alzheimer Model Mice

(2014) Kohei Yuyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exosomes as mediators of neuroinflammation

(2014) Archana Gupta et al.   Journal of Neuroinflammation

Rapid inflammasome activation in microglia contributes to brain disease in HIV/AIDS

(2014) John G Walsh et al.   Retrovirology

Amyloid-β induces NLRP1-dependent neuronal pyroptosis in models of Alzheimer’s disease

(2014) M-S Tan et al.   Cell Death & Disease

HIV and HCV Activate the Inflammasome in Monocytes and Macrophages via Endosomal Toll-Like Receptors without Induction of Type 1 Interferon

(2014) Michael A. Chattergoon et al.   PLoS Pathogens

High-Mobility Group Box-1 Protein and  -Amyloid Oligomers Promote Neuronal Differentiation of Adult Hippocampal Neural Progenitors via Receptor for Advanced Glycation End Products/Nuclear Factor- B Axis: Relevance for Alzheimer's Disease

(2013) V. Meneghini et al.   JOURNAL OF NEUROSCIENCE

Exosomes: Mediators of Neurodegeneration, Neuroprotection and Therapeutics

(2013) Anuradha Kalani et al.   MOLECULAR NEUROBIOLOGY

Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

(2013) Gilad Doitsh et al.   NATURE

Exosomes neutralize synaptic-plasticity-disrupting activity of Aβ assemblies in vivo

(2013) Kyongman An et al.   Molecular Brain

Cerebral β-amyloid deposition predicts HIV-associated neurocognitive disorders in APOE ε4 carriers

(2012) Virawudh Soontornniyomkij et al.   AIDS

Overview and introduction: The blood-brain barrier in health and disease

(2012) N. Joan Abbott et al.   EPILEPSIA

Cognitive impairment in HIV infection is associated with MRI and CSF pattern of neurodegeneration

(2012) F. Steinbrink et al.   EUROPEAN JOURNAL OF NEUROLOGY

HIV-1 alters neural and glial progenitor cell dynamics in the central nervous system: Coordinated response to opiates during maturation

(2012) Yun Kyung Hahn et al.   GLIA

Polymorphisms in Inflammasomeʼ Genes and Susceptibility to HIV-1 Infection

(2012) Alessandra Pontillo et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Sphingolipid-modulated Exosome Secretion Promotes Clearance of Amyloid-β by Microglia

(2012) Kohei Yuyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease

(2012) Rashid Deane et al.   JOURNAL OF CLINICAL INVESTIGATION

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

HIV-1 induces NALP3-inflammasome expression and interleukin-1β secretion in dendritic cells from healthy individuals but not from HIV-positive patients

(2011) Alessandra Pontillo et al.   AIDS

Advanced Glycation End Products Inhibit Both Infection and Transmission In Trans of HIV-1 from Monocyte-Derived Dendritic Cells to Autologous T Cells

(2011) N. Nasreddine et al.   JOURNAL OF IMMUNOLOGY

A 3′UTR SNP in NLRP3 Gene is Associated With Susceptibility to HIV-1 Infection

(2010) Alessandra Pontillo et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Ceramide and Ceramide 1-Phosphate Are Negative Regulators of TNF-  Production Induced by Lipopolysaccharide

(2010) S. Jozefowski et al.   JOURNAL OF IMMUNOLOGY

Differential splicing of the apoptosis-associated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomes

(2010) Nicole B Bryan et al.   Journal of Inflammation-London

Rescue of adult hippocampal neurogenesis in a mouse model of HIV neurologic disease

(2010) Myoung-Hwa Lee et al.   NEUROBIOLOGY OF DISEASE

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Activation of Inflammasomes Requires Intracellular Redistribution of the Apoptotic Speck-Like Protein Containing a Caspase Recruitment Domain

(2009) N. B. Bryan et al.   JOURNAL OF IMMUNOLOGY

HIV Regulation of Amyloid Beta Production

(2009) Lynn Pulliam   Journal of Neuroimmune Pharmacology

Increased Accumulation of Intraneuronal Amyloid β in HIV-Infected Patients

(2009) Cristian L. Achim et al.   Journal of Neuroimmune Pharmacology

HIV-1-induced amyloid beta accumulation in brain endothelial cells is attenuated by simvastatin

(2009) Ibolya E. András et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Adult SVZ Stem Cells Lie in a Vascular Niche: A Quantitative Analysis of Niche Cell-Cell Interactions

(2008) Qin Shen et al.   Cell Stem Cell

Amyloid-β oligomers set fire to inflammasomes and induce Alzheimer's pathology

(2008) Antero Salminen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Triple fluorescence labelling of neuronal, glial and vascular markers revealing pathological alterations in various animal models

(2008) Wolfgang Härtig et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Neurodegeneration and Ageing in the HAART Era

(2008) Bruce J. Brew et al.   Journal of Neuroimmune Pharmacology

The Comorbidity of HIV-Associated Neurocognitive Disorders and Alzheimer’s Disease: A Foreseeable Medical Challenge in Post-HAART Era

(2008) Jiqing Xu et al.   Journal of Neuroimmune Pharmacology

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

(2008) Annett Halle et al.   NATURE IMMUNOLOGY