Overview and introduction: The blood-brain barrier in health and disease

The blood-brain barrier hypothesis in drug resistant epilepsy

(2012) N. Marchi et al.   BRAIN

Do ATP-Binding Cassette Transporters Cause Pharmacoresistance in Epilepsy? Problems and Approaches in Determining which Antiepileptic Drugs are Affected

(2012) Wolfgang Loscher et al.   CURRENT PHARMACEUTICAL DESIGN

Getting to Know the Cast - Cellular Interactions and Signaling at the Neurovascular Unit

(2012) Maarja Mae et al.   CURRENT PHARMACEUTICAL DESIGN

Inflammatory events at blood-brain barrier in neuroinflammatory and neurodegenerative disorders: Implications for clinical disease

(2012) Helga E. de Vries et al.   EPILEPSIA

Cliniconeuropathologic correlations show astroglial albumin storage as a common factor in epileptogenic vascular lesions

(2012) Anna Raabe et al.   EPILEPSIA

Mechanisms underlying blood-brain barrier dysfunction in brain pathology and epileptogenesis: Role of astroglia

(2012) Richard Kovács et al.   EPILEPSIA

Imaging blood-brain barrier dysfunction in animal disease models

(2012) Andreas Wunder et al.   EPILEPSIA

Blood-brain barrier dysfunction-induced inflammatory signaling in brain pathology and epileptogenesis

(2012) Soo Young Kim et al.   EPILEPSIA

Blood-brain barrier dysfunction in brain diseases: Clinical experience

(2012) Karl Schoknecht et al.   EPILEPSIA

Blood-brain barrier dysfunction, TGFβ signaling, and astrocyte dysfunction in epilepsy

(2012) Uwe Heinemann et al.   GLIA

Acetylcholinesterase loosens the brain's cholinergic anti-inflammatory response and promotes epileptogenesis

(2012) Yehudit Gnatek et al.   Frontiers in Molecular Neuroscience

Astrocyte-Derived Thrombospondin-2 Is Critical for the Repair of the Blood-Brain Barrier

(2011) Weiming Tian et al.   AMERICAN JOURNAL OF PATHOLOGY

Mechanisms of Leukocyte Transendothelial Migration

(2011) William A. Muller   Annual Review of Pathology-Mechanisms of Disease

Role of pro-inflammatory cytokines released from microglia in neurodegenerative diseases

(2011) Joshua A. Smith et al.   BRAIN RESEARCH BULLETIN

Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

(2011) Bence György et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Interplay of Drug Metabolizing CYP450 Enzymes and ABC Transporters in the Blood-Brain Barrier

(2011) Xavier Decleves et al.   CURRENT DRUG METABOLISM

Molecular Biology of Nucleoside Transporters and their Distributions and Functions in the Brain

(2011) Fiona E. Parkinson et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Blood-brain barrier dysfunction, status epilepticus, seizures, and epilepsy: A puzzle of a chicken and egg?

(2011) Alon Friedman   EPILEPSIA

The role of free radical generation in increasing cerebrovascular permeability

(2011) Paul A. Fraser   FREE RADICAL BIOLOGY AND MEDICINE

A differential proteomic approach identifies structural and functional components that contribute to the differentiation of brain capillary endothelial cells

(2011) Gwënaël Pottiez et al.   Journal of Proteomics

Transcriptomic and Quantitative Proteomic Analysis of Transporters and Drug Metabolizing Enzymes in Freshly Isolated Human Brain Microvessels

(2011) Ramzi Shawahna et al.   MOLECULAR PHARMACEUTICS

Engaging neuroscience to advance translational research in brain barrier biology

(2011) Edward A. Neuwelt et al.   NATURE REVIEWS NEUROSCIENCE

Impact of seizure activity on free extracellular phenytoin concentrations in amygdala-kindled rats

(2011) Heidrun Potschka et al.   NEUROPHARMACOLOGY

The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence

(2011) J. I. Alvarez et al.   SCIENCE

MicroRNA regulation in angiogenesis

(2011) Andrea Caporali et al.   VASCULAR PHARMACOLOGY

MicroRNAs and vascular (dys)function

(2011) Dorothee Hartmann et al.   VASCULAR PHARMACOLOGY

Kinetic Analysis of the Cooperation of P-Glycoprotein (P-gp/Abcb1) and Breast Cancer Resistance Protein (Bcrp/Abcg2) in Limiting the Brain and Testis Penetration of Erlotinib, Flavopiridol, and Mitoxantrone

(2010) H. Kodaira et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Pericytes are required for blood–brain barrier integrity during embryogenesis

(2010) Richard Daneman et al.   NATURE

Blood–brain barrier breakdown as a therapeutic target in traumatic brain injury

(2010) Dan Shlosberg et al.   Nature Reviews Neurology

Review: Leucocyte-endothelial cell crosstalk at the blood-brain barrier: A prerequisite for successful immune cell entry to the brain

(2010) J. Greenwood et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Transporter hypothesis of drug-resistant epilepsy: challenges for pharmacogenetic approaches

(2010) Heidrun Potschka   PHARMACOGENOMICS

The molecular basis of the blood brain barrier differentiation and maintenance. Is it still a mystery?

(2010) Roberta Paolinelli et al.   PHARMACOLOGICAL RESEARCH

Regulation of P-glycoprotein and other ABC drug transporters at the blood–brain barrier

(2010) David S. Miller   TRENDS IN PHARMACOLOGICAL SCIENCES

Blood-brain barrier breakdown and repair by Src after thrombin-induced injury

(2009) Da-Zhi Liu et al.   ANNALS OF NEUROLOGY

Predicting Ligand Interactions with ABC Transporters in ADME

(2009) Michael A. Demel et al.   CHEMISTRY & BIODIVERSITY

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

Wnt/ -catenin signaling is required for CNS, but not non-CNS, angiogenesis

(2009) R. Daneman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

P-Glycoprotein Senses Its Substrates and the Lateral Membrane Packing Density: Consequences for the Catalytic Cycle†

(2008) Päivi Äänismaa et al.   BIOCHEMISTRY

All vertebrates started out with a glial blood-brain barrier 4-500 million years ago

(2008) Magnus Bundgaard et al.   GLIA

The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state

(2008) Le Shen et al.   JOURNAL OF CELL BIOLOGY

Wnt/β-catenin signaling controls development of the blood–brain barrier

(2008) Stefan Liebner et al.   JOURNAL OF CELL BIOLOGY