HMGB1 Induces Secretion of Matrix Vesicles by Macrophages to Enhance Ectopic Mineralization

The Role of HMGB1 in Cardiovascular Biology: Danger Signals

(2015) Jingjing Cai et al.   ANTIOXIDANTS & REDOX SIGNALING

Matrix vesicles: Are they anchored exosomes?

(2015) Irving M. Shapiro et al.   BONE

Vascular Smooth Muscle Cell Calcification Is Mediated by Regulated Exosome Secretion

(2015) A. N. Kapustin et al.   CIRCULATION RESEARCH

Osteopontin alters endothelial and valvular interstitial cell behaviour in calcific aortic valve stenosis through HMGB1 regulation

(2015) Margaret Passmore et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth

(2015) Jess Morhayim et al.   FASEB JOURNAL

Pathophysiological Role of Vascular Smooth Muscle Alkaline Phosphatase in Medial Artery Calcification

(2015) Campbell R Sheen et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Platelet-derived HMGB1 is a critical mediator of thrombosis

(2015) Sebastian Vogel et al.   JOURNAL OF CLINICAL INVESTIGATION

Extracellular Signal-regulated Kinase Mitogen-activated Protein Kinase and Phosphatidylinositol 3-Kinase/Akt Signaling Are Required for Lipopolysaccharide-mediated Mineralization in Murine Odontoblast-like Cells

(2015) Zhihua Wang et al.   JOURNAL OF ENDODONTICS

Acute phase serum amyloid A induces proinflammatory cytokines and mineralization via toll-like receptor 4 in mesenchymal stem cells

(2015) Regina Ebert et al.   Stem Cell Research

HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi

(2015) Michael Bode et al.   THROMBOSIS AND HAEMOSTASIS

Has Our Understanding of Calcification in Human Coronary Atherosclerosis Progressed?

(2014) Fumiyuki Otsuka et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Extracellular HMGB1 promotes differentiation of nurse-like cells in chronic lymphocytic leukemia

(2014) L. Jia et al.   BLOOD

Ectopic calcification in diabetic vascular disease

(2014) Angelo Avogaro et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Sphingolipid metabolites in inflammatory disease

(2014) Michael Maceyka et al.   NATURE

Transglutaminase 2 Accelerates Vascular Calcification in Chronic Kidney Disease

(2013) Neal X. Chen et al.   AMERICAN JOURNAL OF NEPHROLOGY

Role of Extracellular Vesicles in De Novo Mineralization

(2013) Sophie E. P. New et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Macrophage-Derived Matrix Vesicles

(2013) Sophie E. P. New et al.   CIRCULATION RESEARCH

HMGB1 in Cancer: Good, Bad, or Both?

(2013) R. Kang et al.   CLINICAL CANCER RESEARCH

High Mobility Group Box 1 (HMGB1) Mediates High-Glucose-Induced Calcification in Vascular Smooth Muscle Cells of Saphenous Veins

(2013) Yongyi Wang et al.   INFLAMMATION

Effects of high-mobility group box 1 on the proliferation and odontoblastic differentiation of human dental pulp cells

(2013) S. C. Qi et al.   INTERNATIONAL ENDODONTIC JOURNAL

Ectopic mineralization disorders of the extracellular matrix of connective tissue: Molecular genetics and pathomechanisms of aberrant calcification

(2013) Qiaoli Li et al.   MATRIX BIOLOGY

RAGE and TLRs: Relatives, friends or neighbours?

(2013) Zaridatul Aini Ibrahim et al.   MOLECULAR IMMUNOLOGY

Macrophages play a unique role in the plaque calcification by enhancing the osteogenic signals exerted by vascular smooth muscle cells

(2012) Koji Ikeda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

HMGB1: A multifunctional alarmin driving autoimmune and inflammatory disease

(2012) Helena Erlandsson Harris et al.   Nature Reviews Rheumatology

Calcium Regulates Key Components of Vascular Smooth Muscle Cell–Derived Matrix Vesicles to Enhance Mineralization

(2011) Alexander N. Kapustin et al.   CIRCULATION RESEARCH

Neutral Sphingomyelinase 2 Activity and Protein Stability Are Modulated by Phosphorylation of Five Conserved Serines

(2011) Simone Filosto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Matrix vesicles are carriers of bone morphogenetic proteins (BMPs), vascular endothelial growth factor (VEGF), and noncollagenous matrix proteins

(2011) Niru N. Nahar et al.   JOURNAL OF BONE AND MINERAL METABOLISM

A cell-autonomous requirement for neutral sphingomyelinase 2 in bone mineralization

(2011) Zohreh Khavandgar et al.   JOURNAL OF CELL BIOLOGY

High-Mobility Group Box Protein 1 Neutralization Reduces Development of Diet-Induced Atherosclerosis in Apolipoprotein E–Deficient Mice

(2010) Peter Kanellakis et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

S100A12 in Vascular Smooth Muscle Accelerates Vascular Calcification in Apolipoprotein E–Null Mice by Activating an Osteogenic Gene Regulatory Program

(2010) Marion A. Hofmann Bowman et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Proteomic analysis of articular cartilage vesicles from normal and osteoarthritic cartilage

(2010) Ann K. Rosenthal et al.   ARTHRITIS AND RHEUMATISM

Biomineralization and matrix vesicles in biology and pathology

(2010) Ellis E. Golub   Seminars in Immunopathology

Role of matrix vesicles in biomineralization

(2009) Ellis E. Golub   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

p38 mitogen-activated protein kinase targets the production of proinflammatory endothelial microparticles

(2009) A. M. CURTIS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

HMGB1 Regulates RANKL-Induced Osteoclastogenesis in a Manner Dependent on RAGE

(2008) Zheng Zhou et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Annexin-Mediated Matrix Vesicle Calcification in Vascular Smooth Muscle Cells

(2008) Neal X Chen et al.   JOURNAL OF BONE AND MINERAL RESEARCH