Tetrahydrobenzimidazole TMQ0153 triggers apoptosis, autophagy and necroptosis crosstalk in chronic myeloid leukemia

Natural modulators of the hallmarks of immunogenic cell death

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Redox biology of regulated cell death in cancer: A focus on necroptosis and ferroptosis

(2019) Cristina Florean et al.   FREE RADICAL BIOLOGY AND MEDICINE

Integrins and ERp57 Coordinate to Regulate Cell Surface Calreticulin in Immunogenic Cell Death

(2019) Chi-Chao Liu et al.   Frontiers in Oncology

Chronic myeloid leukemia: 2018 update on diagnosis, therapy and monitoring

(2018) Elias Jabbour et al.   AMERICAN JOURNAL OF HEMATOLOGY

Stress-induced cellular responses in immunogenic cell death: Implications for cancer immunotherapy

(2018) Flavia Radogna et al.   BIOCHEMICAL PHARMACOLOGY

The dialkyl resorcinol stemphol disrupts calcium homeostasis to trigger programmed immunogenic necrosis in cancer

(2018) Seungwon Ji et al.   CANCER LETTERS

Cytostatic hydroxycoumarin OT52 induces ER/Golgi stress and STAT3 inhibition triggering non-canonical cell death and synergy with BH3 mimetics in lung cancer

(2018) Jin-Young Lee et al.   CANCER LETTERS

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

(2018) Lorenzo Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Oxidative stress alters mitochondrial bioenergetics and modifies pancreatic cell death independently of cyclophilin D, resulting in an apoptosis-to-necrosis shift

(2018) Jane A. Armstrong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutathione depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells

(2018) Yun Sun et al.   Cell Death & Disease

Lysosomal damage after spinal cord injury causes accumulation of RIPK1 and RIPK3 proteins and potentiation of necroptosis

(2018) Shuo Liu et al.   Cell Death & Disease

Cardiac Glycoside Glucoevatromonoside Induces Cancer Type-Specific Cell Death

(2018) Naira F. Z. Schneider et al.   Frontiers in Pharmacology

Preclinical Assessment of the Bioactivity of the Anticancer Coumarin OT48 by Spheroids, Colony Formation Assays, and Zebrafish Xenografts

(2018) Jin-Young Lee et al.   Jove-Journal of Visualized Experiments

Hydroxycoumarin OT-55 kills CML cells alone or in synergy with imatinib or Synribo: Involvement of ER stress and DAMP release

(2018) Aloran Mazumder et al.   CANCER LETTERS

Crashing the computer: apoptosis vs. necroptosis in neuroinflammation

(2018) Bradlee L. Heckmann et al.   CELL DEATH AND DIFFERENTIATION

Unaromatized Tetrahydrobenzimidazole Synthesis from p -Benzoquinone and N -Arylamidines and their Cytotoxic Potential

(2018) Minh Quan Tran et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Shikonin-induced necroptosis is enhanced by the inhibition of autophagy in non-small cell lung cancer cells

(2017) Hyo-Jin Kim et al.   Journal of Translational Medicine

Autophagy Inhibition Improves Sunitinib Efficacy in Pancreatic Neuroendocrine Tumors via a Lysosome-dependent Mechanism

(2017) Tabea Wiedmer et al.   MOLECULAR CANCER THERAPEUTICS

From the Cover: ROS-Induced Store-Operated Ca2+ Entry Coupled to PARP-1 Hyperactivation Is Independent of PARG Activity in Necrotic Cell Death

(2017) Frances M. Munoz et al.   TOXICOLOGICAL SCIENCES

ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells

(2016) Maria Karvela et al.   Autophagy

4-Hydroxybenzoic acid derivatives as HDAC6-specific inhibitors modulating microtubular structure and HSP90α chaperone activity against prostate cancer

(2016) Carole Seidel et al.   BIOCHEMICAL PHARMACOLOGY

Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics

(2015) Gi-Bang Koo et al.   CELL RESEARCH

Mitochondria-targeted antioxidants

(2015) Anne O. Oyewole et al.   FASEB JOURNAL

Immunogenic cell death

(2015) Abhishek D. Garg et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Glutathione Depletion Induces Spermatogonial Cell Autophagy

(2015) Héctor Mancilla et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

N-Acetylcysteine improves mitochondrial function and ameliorates behavioral deficits in the R6/1 mouse model of Huntington's disease

(2015) D J Wright et al.   Translational Psychiatry

Plumbagin Modulates Leukemia Cell Redox Status

(2014) François Gaascht et al.   MOLECULES

Regulated necrosis: the expanding network of non-apoptotic cell death pathways

(2014) Tom Vanden Berghe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

β-Lapachone induces programmed necrosis through the RIP1-PARP-AIF-dependent pathway in human hepatocellular carcinoma SK-Hep1 cells

(2014) E J Park et al.   Cell Death & Disease

Functional interaction between autophagy and ciliogenesis

(2013) Olatz Pampliega et al.   NATURE

Immunogenic Cell Death in Cancer Therapy

(2012) Guido Kroemer et al.   Annual Review of Immunology

Glutathione Efflux and Cell Death

(2012) Rodrigo Franco et al.   ANTIOXIDANTS & REDOX SIGNALING

Imatinib and Nilotinib inhibit Bcr–Abl-induced ROS through targeted degradation of the NADPH oxidase subunit p22phox

(2012) William D. Landry et al.   LEUKEMIA RESEARCH

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

New frontiers in promoting tumour cell death: targeting apoptosis, necroptosis and autophagy

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Autophagic cell death: Loch Ness monster or endangered species?

(2011) Han-Ming Shen et al.   Autophagy

Chemotherapeutic agents circumvent emergence of dasatinib-resistant BCR-ABL kinase mutations in a precise mouse model of Philadelphia chromosome-positive acute lymphoblastic leukemia

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N-acetylcysteine, reactive oxygen species and beyond

(2010) Shi-Yong Sun   CANCER BIOLOGY & THERAPY

Clinical Utility of Microarray-Based Gene Expression Profiling in the Diagnosis and Subclassification of Leukemia: Report From the International Microarray Innovations in Leukemia Study Group

(2010) Torsten Haferlach et al.   JOURNAL OF CLINICAL ONCOLOGY

NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases

(2010) M M Reddy et al.   LEUKEMIA

Akt and Autophagy Cooperate to Promote Survival of Drug-Resistant Glioma

(2010) Q.-W. Fan et al.   Science Signaling

Antioxidant Activity of Vitamin E and Trolox: Understanding of the Factors that Govern Lipid Peroxidation Studies In Vitro

(2009) Marlene Lúcio et al.   Food Biophysics

Lipoxygenase-mediated pro-radical effect of melatonin via stimulation of arachidonic acid metabolism

(2009) F. Radogna et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

An international standardization programme towards the application of gene expression profiling in routine leukaemia diagnostics: the Microarray Innovations in LEukemia study prephase

(2008) Alexander Kohlmann et al.   BRITISH JOURNAL OF HAEMATOLOGY

Biological Roles for the NOX Family NADPH Oxidases

(2008) William M. Nauseef   JOURNAL OF BIOLOGICAL CHEMISTRY