标题
Lysosomal size matters
作者
关键词
-
出版物
TRAFFIC
Volume 21, Issue 1, Pages 60-75
出版商
Wiley
发表日期
2019-11-06
DOI
10.1111/tra.12714
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Phosphatidylinositol 4,5‐bisphosphate controls Rab7 and PLEKMH1 membrane cycling during autophagosome–lysosome fusion
- (2019) Takashi Baba et al. EMBO JOURNAL
- The lysosomal GPCR-like protein GPR137B regulates Rag and mTORC1 localization and activity
- (2019) Lin Gan et al. NATURE CELL BIOLOGY
- BORC regulates late endosomal/lysosomal size through PIKfyve‐dependent phosphatidylinositol‐3,5‐bisphosphate
- (2019) Teodor E. Yordanov et al. TRAFFIC
- Mouse models and strain-dependency of Chédiak-Higashi syndrome-associated neurologic dysfunction
- (2019) Adam Hedberg-Buenz et al. Scientific Reports
- ZnT2 is critical for lysosome acidification and biogenesis during mammary gland involution
- (2018) Olivia C Rivera et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency
- (2018) Parisa Lotfi et al. Autophagy
- A negative feedback regulation of MTORC1 activity by the lysosomal Ca2+ channel MCOLN1 (mucolipin 1) using a CALM (calmodulin)-dependent mechanism
- (2018) Xue Sun et al. Autophagy
- Lysosome enlargement during inhibition of the lipid kinase PIKfyve proceeds through lysosome coalescence
- (2018) Christopher H. Choy et al. JOURNAL OF CELL SCIENCE
- Inhibition of TBC1D5 activates Rab7a and can enhance the function of the retromer cargo-selective complex
- (2018) Matthew N. J. Seaman et al. JOURNAL OF CELL SCIENCE
- Mitochondria–lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis
- (2018) Yvette C. Wong et al. NATURE
- TBC1D5 controls the GTPase cycle of Rab7b
- (2018) Marita Borg Distefano et al. JOURNAL OF CELL SCIENCE
- A Mutation in the Borcs7 Subunit of the Lysosome Regulatory BORC Complex Results in Motor Deficits and Dystrophic Axonopathy in Mice
- (2018) John N. Snouwaert et al. Cell Reports
- The lysosome as a cellular centre for signalling, metabolism and quality control
- (2018) Rosalie E. Lawrence et al. NATURE CELL BIOLOGY
- Zinc transporter 2 interacts with vacuolar ATPase and is required for polarization, vesicle acidification, and secretion in mammary epithelial cells
- (2017) Sooyeon Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The lysosomal Ca2+release channel TRPML1 regulates lysosome size by activating calmodulin
- (2017) Qi Cao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Ragulator–BORC interaction controls lysosome positioning in response to amino acid availability
- (2017) Jing Pu et al. JOURNAL OF CELL BIOLOGY
- LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning
- (2017) Przemyslaw A. Filipek et al. JOURNAL OF CELL BIOLOGY
- Tuning the ion selectivity of two-pore channels
- (2017) Jiangtao Guo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PIKfyve activity regulates reformation of terminal storage lysosomes from endolysosomes
- (2017) Christin Bissig et al. TRAFFIC
- Stop or Go? Endosome Positioning in the Establishment of Compartment Architecture, Dynamics, and Function
- (2017) Jacques Neefjes et al. TRENDS IN CELL BIOLOGY
- mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases
- (2017) Michela Palmieri et al. Nature Communications
- Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding
- (2017) Manuel Alonso Y Adell et al. eLife
- Differences in Granule Morphology yet Equally Impaired Exocytosis among Cytotoxic T Cells and NK Cells from Chediak–Higashi Syndrome Patients
- (2017) Samuel C. C. Chiang et al. Frontiers in Immunology
- The Lysosome as a Regulatory Hub
- (2016) Rushika M. Perera et al. Annual Review of Cell and Developmental Biology
- Regulation of lysosomal phosphoinositide balance by INPP5E is essential for autophagosome–lysosome fusion
- (2016) Shuhei Nakamura et al. Autophagy
- Endolysosomes Are the Principal Intracellular Sites of Acid Hydrolase Activity
- (2016) Nicholas A. Bright et al. CURRENT BIOLOGY
- PIKfyve Regulates Vacuole Maturation and Nutrient Recovery following Engulfment
- (2016) Shefali Krishna et al. DEVELOPMENTAL CELL
- Kinesin 1 Drives Autolysosome Tubulation
- (2016) Wanqing Du et al. DEVELOPMENTAL CELL
- Autophagosome–lysosome fusion in neurons requires INPP5E, a protein associated with Joubert syndrome
- (2016) Junya Hasegawa et al. EMBO JOURNAL
- Autophagic lysosome reformation dysfunction in glucocerebrosidase deficient cells: relevance to Parkinson disease
- (2016) Joana Magalhaes et al. HUMAN MOLECULAR GENETICS
- The position of lysosomes within the cell determines their luminal pH
- (2016) Danielle E. Johnson et al. JOURNAL OF CELL BIOLOGY
- Mechanisms and functions of lysosome positioning
- (2016) Jing Pu et al. JOURNAL OF CELL SCIENCE
- Lysosomal trafficking regulator Lyst links membrane trafficking to toll-like receptor–mediated inflammatory responses
- (2016) Andreas Westphal et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Drug development: Through the barrier
- (2016) Sarah DeWeerdt NATURE
- A molecular mechanism to regulate lysosome motility for lysosome positioning and tubulation
- (2016) Xinran Li et al. NATURE CELL BIOLOGY
- BORC Functions Upstream of Kinesins 1 and 3 to Coordinate Regional Movement of Lysosomes along Different Microtubule Tracks
- (2016) Carlos M. Guardia et al. Cell Reports
- The GATOR2 Component Wdr24 Regulates TORC1 Activity and Lysosome Function
- (2016) Weili Cai et al. PLoS Genetics
- Vesicle Size Regulates Nanotube Formation in the Cell
- (2016) Qian Peter Su et al. Scientific Reports
- The mucolipidosis IV Ca2+ channel TRPML1 (MCOLN1) is regulated by the TOR kinase
- (2015) R. U. Onyenwoke et al. BIOCHEMICAL JOURNAL
- TPC: the NAADP discovery channel?: Figure 1
- (2015) Anthony J. Morgan et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- BORC, a Multisubunit Complex that Regulates Lysosome Positioning
- (2015) Jing Pu et al. DEVELOPMENTAL CELL
- mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival
- (2015) M. J. Munson et al. EMBO JOURNAL
- Vacuolar ATPase in Phagosome-Lysosome Fusion
- (2015) Sandra Kissing et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PI(3,5)P2controls endosomal branched actin dynamics by regulating cortactin–actin interactions
- (2015) Nan Hyung Hong et al. JOURNAL OF CELL BIOLOGY
- The small GTPase Arl8b regulates assembly of the mammalian HOPS complex on lysosomes
- (2015) D. Khatter et al. JOURNAL OF CELL SCIENCE
- Ultrastructural Morphometry Points to a New Role for LAMTOR2 in Regulating the Endo/Lysosomal System
- (2015) Georg F. Vogel et al. TRAFFIC
- In Vivo Evidence for Lysosome Depletion and Impaired Autophagic Clearance in Hereditary Spastic Paraplegia Type SPG11
- (2015) Rita-Eva Varga et al. PLoS Genetics
- ER Contact Sites Define the Position and Timing of Endosome Fission
- (2014) Ashley A. Rowland et al. CELL
- The general amino acid control pathway regulates mTOR and autophagy during serum/glutamine starvation
- (2014) Rui Chen et al. JOURNAL OF CELL BIOLOGY
- Dictyostelium LvsB has a regulatory role in endosomal vesicle fusion
- (2014) Kristin Falkenstein et al. JOURNAL OF CELL SCIENCE
- Spastic paraplegia proteins spastizin and spatacsin mediate autophagic lysosome reformation
- (2014) Jaerak Chang et al. JOURNAL OF CLINICAL INVESTIGATION
- Lysosome size, motility and stress response regulated by fronto-temporal dementia modifier TMEM106B
- (2014) Massimiliano Stagi et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- The signaling lipid PI(3,5)P2 stabilizes V1–Vo sector interactions and activates the V-ATPase
- (2014) Sheena Claire Li et al. MOLECULAR BIOLOGY OF THE CELL
- Sphingolipid lysosomal storage disorders
- (2014) Frances M. Platt NATURE
- Molecular genetics and cellular features of TFE3 and TFEB fusion kidney cancers
- (2014) Eric C. Kauffman et al. Nature Reviews Urology
- Lysosome Transport as a Function of Lysosome Diameter
- (2014) Debjyoti Bandyopadhyay et al. PLoS One
- LYST Affects Lysosome Size and Quantity, but not Trafficking or Degradation Through Autophagy or Endocytosis
- (2014) Petter Holland et al. TRAFFIC
- Regulation of mTORC1 by amino acids
- (2014) Liron Bar-Peled et al. TRENDS IN CELL BIOLOGY
- Rag GTPases are cardioprotective by regulating lysosomal function
- (2014) Young Chul Kim et al. Nature Communications
- A small molecule restores function to TRPML1 mutant isoforms responsible for mucolipidosis type IV
- (2014) Cheng-Chang Chen et al. Nature Communications
- Homotypic Vacuole Fusion in Yeast Requires Organelle Acidification and Not the V-ATPase Membrane Domain
- (2013) Emily M. Coonrod et al. DEVELOPMENTAL CELL
- Transcription factor EB (TFEB) is a new therapeutic target for Pompe disease
- (2013) Carmine Spampanato et al. EMBO Molecular Medicine
- TFEB regulates lysosomal proteostasis
- (2013) Wensi Song et al. HUMAN MOLECULAR GENETICS
- The lysosomal signaling anchor p18/LAMTOR1 controls epidermal development by regulating lysosome-mediated catabolic processes
- (2013) T. Soma-Nagae et al. JOURNAL OF CELL SCIENCE
- Signals from the lysosome: a control centre for cellular clearance and energy metabolism
- (2013) Carmine Settembre et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Critical roles of type III phosphatidylinositol phosphate kinase in murine embryonic visceral endoderm and adult intestine
- (2013) S. Takasuga et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A mechanism for retromer endosomal coat complex assembly with cargo
- (2013) M. S. Harrison et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TFEB-mediated autophagy rescues midbrain dopamine neurons from -synuclein toxicity
- (2013) M. Decressac et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Antagonistic Control of Lysosomal Fusion by Rab14 and the Lyst-Related Protein LvsB
- (2013) Elena Kypri et al. TRAFFIC
- Tethering the assembly of SNARE complexes
- (2013) WanJin Hong et al. TRENDS IN CELL BIOLOGY
- TPC Proteins Are Phosphoinositide- Activated Sodium-Selective Ion Channels in Endosomes and Lysosomes
- (2012) Xiang Wang et al. CELL
- The lipid kinase PI4KIIIβ preserves lysosomal identity
- (2012) Sunandini Sridhar et al. EMBO JOURNAL
- The frontotemporal lobar degeneration risk factor, TMEM106B, regulates lysosomal morphology and function
- (2012) Owen A. Brady et al. HUMAN MOLECULAR GENETICS
- Neuronal expression of Fig4 is both necessary and sufficient to prevent spongiform neurodegeneration
- (2012) C. J. Ferguson et al. HUMAN MOLECULAR GENETICS
- New strategies for the treatment of lysosomal storage diseases (Review)
- (2012) GIANCARLO PARENTI et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Membrane Orientation and Subcellular Localization of Transmembrane Protein 106B (TMEM106B), a Major Risk Factor for Frontotemporal Lobar Degeneration
- (2012) Christina M. Lang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Class II formin targeting to the cell cortex by binding PI(3,5)P2is essential for polarized growth
- (2012) Peter A.C. van Gisbergen et al. JOURNAL OF CELL BIOLOGY
- Lysosomal storage disorders: The cellular impact of lysosomal dysfunction
- (2012) Frances M. Platt et al. JOURNAL OF CELL BIOLOGY
- The late endosomal adaptor p14 is a macrophage host-defense factor against Salmonella infection
- (2012) N. Taub et al. JOURNAL OF CELL SCIENCE
- TMEM106B, the Risk Gene for Frontotemporal Dementia, Is Regulated by the microRNA-132/212 Cluster and Affects Progranulin Pathways
- (2012) A. S. Chen-Plotkin et al. JOURNAL OF NEUROSCIENCE
- Phosphatidylinositol 3,5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1
- (2012) Dave Bridges et al. MOLECULAR BIOLOGY OF THE CELL
- Cell-free reconstitution of vacuole membrane fragmentation reveals regulation of vacuole size and number by TORC1
- (2012) Lydie Michaillat et al. MOLECULAR BIOLOGY OF THE CELL
- Clathrin and phosphatidylinositol-4,5-bisphosphate regulate autophagic lysosome reformation
- (2012) Yueguang Rong et al. NATURE CELL BIOLOGY
- Cancer-associated lysosomal changes: friends or foes?
- (2012) T Kallunki et al. ONCOGENE
- Phosphoinositide isoforms determine compartment-specific ion channel activity
- (2012) X. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fig4 deficiency: A newly emerged lysosomal storage disorder?
- (2012) Colin Martyn et al. PROGRESS IN NEUROBIOLOGY
- Drosophila mauveMutants Reveal a Role of LYST Homologs Late in the Maturation of Phagosomes and Autophagosomes
- (2012) Mokhlasur Rahman et al. TRAFFIC
- Lipid storage disorders block lysosomal trafficking by inhibiting a TRP channel and lysosomal calcium release
- (2012) Dongbiao Shen et al. Nature Communications
- Lysosomal Acidification Mechanisms
- (2011) Joseph A. Mindell Annual Review of Physiology
- The late endosome/lysosome-anchored p18-mTORC1 pathway controls terminal maturation of lysosomes
- (2011) Yusuke Takahashi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The V-ATPase proteolipid cylinder promotes the lipid-mixing stage of SNARE-dependent fusion of yeast vacuoles
- (2011) Bernd Strasser et al. EMBO JOURNAL
- Endosome maturation
- (2011) Jatta Huotari et al. EMBO JOURNAL
- Phosphoinositide [PI(3,5)P2] lipid-dependent regulation of the general transcriptional regulator Tup1
- (2011) B.-K. Han et al. GENES & DEVELOPMENT
- The Phosphoinositide Kinase PIKfyve Is Vital in Early Embryonic Development
- (2011) Ognian C. Ikonomov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Biology and Clinical Relevance of the Micropthalmia Family of Transcription Factors in Human Cancer
- (2011) Rizwan Haq et al. JOURNAL OF CLINICAL ONCOLOGY
- Spinster is required for autophagic lysosome reformation and mTOR reactivation following starvation
- (2011) Y. Rong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exploring the link between glucocerebrosidase mutations and parkinsonism
- (2011) Wendy Westbroek et al. TRENDS IN MOLECULAR MEDICINE
- Lysosomal membrane proteins: life between acid and neutral conditions: Figure 1
- (2010) Paul Saftig et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
- (2010) Yasemin Sancak et al. CELL
- Identification of the Switch in Early-to-Late Endosome Transition
- (2010) Dmitry Poteryaev et al. CELL
- Multisubunit Tethering Complexes and Their Role in Membrane Fusion
- (2010) Cornelia Bröcker et al. CURRENT BIOLOGY
- Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders
- (2010) Alessandro Fraldi et al. EMBO JOURNAL
- Termination of autophagy and reformation of lysosomes regulated by mTOR
- (2010) Li Yu et al. NATURE
- V-ATPase Membrane Sector Associates with Synaptobrevin to Modulate Neurotransmitter Release
- (2010) Jérôme Di Giovanni et al. NEURON
- Modulation of Local PtdIns3P Levels by the PI Phosphatase MTMR3 Regulates Constitutive Autophagy
- (2010) Naoko Taguchi-Atarashi et al. TRAFFIC
- PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome
- (2010) Xian-ping Dong et al. Nature Communications
- Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2
- (2009) Cole J. Ferguson et al. HUMAN MOLECULAR GENETICS
- The Clavesin Family, Neuron-specific Lipid- and Clathrin-binding Sec14 Proteins Regulating Lysosomal Morphology
- (2009) Yohei Katoh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7–RILP–p150Gluedand late endosome positioning
- (2009) Nuno Rocha et al. JOURNAL OF CELL BIOLOGY
- Neuropathology of the Mcoln1−/− Knockout Mouse Model of Mucolipidosis Type IV
- (2009) Matthew C. Micsenyi et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- NAADP mobilizes calcium from acidic organelles through two-pore channels
- (2009) Peter J. Calcraft et al. NATURE
- Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function
- (2009) Paul Saftig et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease
- (2009) E. Sidransky et al. NEW ENGLAND JOURNAL OF MEDICINE
- PIKfyve Regulation of Endosome-Linked Pathways
- (2009) Jane de Lartigue et al. TRAFFIC
- Molecular basis of multiple sulfatase deficiency, mucolipidosis II/III and Niemann–Pick C1 disease — Lysosomal storage disorders caused by defects of non-lysosomal proteins
- (2008) Thomas Dierks et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Lysosomal disorders: From storage to cellular damage
- (2008) Andrea Ballabio et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Mutation of FIG4 causes a rapidly progressive, asymmetric neuronal degeneration
- (2008) Xuebao Zhang et al. BRAIN
- VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P2 in yeast and mouse
- (2008) Natsuko Jin et al. EMBO JOURNAL
- The vacuolar V1/V0-ATPase is involved in the release of the HOPS subunit Vps41 from vacuoles, vacuole fragmentation and fusion
- (2008) Kozue Takeda et al. FEBS LETTERS
- Kinesin Adapter JLP Links PIKfyve to Microtubule-based Endosome-to-Trans-Golgi Network Traffic of Furin
- (2008) Ognian C. Ikonomov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7
- (2008) Raul Rojas et al. JOURNAL OF CELL BIOLOGY
- TRP-ML1 functions as a lysosomal NAADP-sensitive Ca2+ release channel in coronary arterial myocytes
- (2008) Fan Zhang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- ArPIKfyve Homomeric and Heteromeric Interactions Scaffold PIKfyve and Sac3 in a Complex to Promote PIKfyve Activity and Functionality
- (2008) Diego Sbrissa et al. JOURNAL OF MOLECULAR BIOLOGY
- The role of AMPK in psychosine mediated effects on oligodendrocytes and astrocytes: implication for Krabbe Disease
- (2008) Shailendra Giri et al. JOURNAL OF NEUROCHEMISTRY
- The Chaperone-Mediated Autophagy Receptor Organizes in Dynamic Protein Complexes at the Lysosomal Membrane
- (2008) U. Bandyopadhyay et al. MOLECULAR AND CELLULAR BIOLOGY
- AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
- (2008) Dana M. Gwinn et al. MOLECULAR CELL
- The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes
- (2008) Austin R. Graves et al. NATURE
- Regulation of TORC1 by Rag GTPases in nutrient response
- (2008) Eunjung Kim et al. NATURE CELL BIOLOGY
- The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1
- (2008) Y. Sancak et al. SCIENCE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started