标题
Hypoxia: A Double-Edged Sword in Cancer Therapy
作者
关键词
-
出版物
CANCER INVESTIGATION
Volume 34, Issue 10, Pages 536-545
出版商
Informa UK Limited
发表日期
2016-11-09
DOI
10.1080/07357907.2016.1245317
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Targeting the hypoxic fraction of tumours using hypoxia-activated prodrugs
- (2016) Roger M. Phillips CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Hypoxia-inducible factor 1–mediated characteristic features of cancer cells for tumor radioresistance
- (2016) Hiroshi Harada JOURNAL OF RADIATION RESEARCH
- Efficacy and safety of the hypoxia-activated prodrug TH-302 in combination with gemcitabine and nab-paclitaxel in human tumor xenograft models of pancreatic cancer
- (2015) Jessica D Sun et al. CANCER BIOLOGY & THERAPY
- Prolyl hydroxylase inhibitors act as agents to enhance the efficiency of cell therapy
- (2015) Maryam Esfahani et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Progress toward overcoming hypoxia-induced resistance to solid tumor therapy
- (2015) Mauricio Reginato et al. Cancer Management and Research
- Targeting hypoxia at the forefront of anticancer immune responses
- (2015) Muhammad Zaeem Noman et al. OncoImmunology
- Defining normoxia, physoxia and hypoxia in tumours—implications for treatment response
- (2014) S R McKeown BRITISH JOURNAL OF RADIOLOGY
- Hypoxia-inducible factors in regulation of immune responses in tumour microenvironment
- (2014) Vinit Kumar et al. IMMUNOLOGY
- PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation
- (2014) Muhammad Zaeem Noman et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Transition metal complexes with bioactive ligands: mechanisms for selective ligand release and applications for drug delivery
- (2014) Anna K. Renfrew Metallomics
- Hypoxia-regulated microRNAs in human cancer
- (2013) Guomin Shen et al. ACTA PHARMACOLOGICA SINICA
- Bioreductive prodrugs as cancer therapeutics: targeting tumor hypoxia
- (2013) Christopher P. Guise et al. Chinese Journal of Cancer
- Design of Optimized Hypoxia-Activated Prodrugs Using Pharmacokinetic/Pharmacodynamic Modeling
- (2013) Annika Foehrenbacher et al. Frontiers in Oncology
- Cancer cells that survive radiation therapy acquire HIF-1 activity and translocate towards tumour blood vessels
- (2012) Hiroshi Harada et al. Nature Communications
- Microenvironment and Radiation Therapy
- (2012) Michio Yoshimura et al. Biomed Research International
- Introduction of hypoxia-targeting p53 fusion protein for the selective therapy of non-small cell lung cancer
- (2011) Yu Zhao et al. CANCER BIOLOGY & THERAPY
- Hypoxia Induces Escape from Innate Immunity in Cancer Cells via Increased Expression of ADAM10: Role of Nitric Oxide
- (2011) I. B. Barsoum et al. CANCER RESEARCH
- Selective Tumor Hypoxia Targeting by Hypoxia-Activated Prodrug TH-302 Inhibits Tumor Growth in Preclinical Models of Cancer
- (2011) J. D. Sun et al. CLINICAL CANCER RESEARCH
- Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of TH-302, a Hypoxia-Activated Prodrug, in Patients with Advanced Solid Malignancies
- (2011) G. J. Weiss et al. CLINICAL CANCER RESEARCH
- Hypoxia-mediated drug resistance: Novel insights on the functional interaction of HIFs and cell death pathways
- (2011) Nadine Rohwer et al. DRUG RESISTANCE UPDATES
- Molecular and Cellular Pharmacology of the Hypoxia-Activated Prodrug TH-302
- (2011) F. Meng et al. MOLECULAR CANCER THERAPEUTICS
- Macrophage Expression of Hypoxia-Inducible Factor-1 Suppresses T-Cell Function and Promotes Tumor Progression
- (2010) A. L. Doedens et al. CANCER RESEARCH
- Hypoxia and Hypoxia-Inducible Factors: Master Regulators of Metastasis
- (2010) X. Lu et al. CLINICAL CANCER RESEARCH
- Hypoxia-activated prodrugs in cancer therapy: progress to the clinic
- (2010) William A Denny Future Oncology
- The remarkable yin and yang of tumour hypoxia
- (2010) Martin Brown INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Hypoxia-specific gene expression for ischemic disease gene therapy
- (2009) Hyun Ah Kim et al. ADVANCED DRUG DELIVERY REVIEWS
- Suppression of Hypoxia-Inducible Factor 2 Restores p53 Activity via Hdm2 and Reverses Chemoresistance of Renal Carcinoma Cells
- (2009) A. M. Roberts et al. CANCER RESEARCH
- Role of hypoxia in the hallmarks of human cancer
- (2009) Kai Ruan et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer
- (2009) S. Ostrand-Rosenberg et al. JOURNAL OF IMMUNOLOGY
- Hypoxia-Selective Targeting by the Bioreductive Prodrug AQ4N in Patients with Solid Tumors: Results of a Phase I Study
- (2008) M. R. Albertella et al. CLINICAL CANCER RESEARCH
- Human dendritic cells differentiated in hypoxia down-modulate antigen uptake and change their chemokine expression profile
- (2008) Angela Rita Elia et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Efficacy of novel hypoxic cell sensitiser doranidazole in the treatment of locally advanced pancreatic cancer: Long-term results of a placebo-controlled randomised study
- (2008) Katsuyuki Karasawa et al. RADIOTHERAPY AND ONCOLOGY
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