Structure of SAGA and mechanism of TBP deposition on gene promoters

The EMBL-EBI search and sequence analysis tools APIs in 2019

(2019) Fábio Madeira et al.   NUCLEIC ACIDS RESEARCH

Chaperone-mediated ordered assembly of the SAGA and NuA4 transcription co-activator complexes in yeast

(2019) Alberto Elías-Villalobos et al.   Nature Communications

cisTEM, user-friendly software for single-particle image processing

(2018) Timothy Grant et al.   eLife

Distinct requirements of linker DNA and transcriptional activators in promoting SAGA-mediated nucleosome acetylation

(2018) Chitvan Mittal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2

(2018) Jian Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of human TFIID and mechanism of TBP loading onto promoter DNA

(2018) Avinash B. Patel et al.   SCIENCE

Molecular structure of promoter-bound yeast TFIID

(2018) Olga Kolesnikova et al.   Nature Communications

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

SAGA Is a General Cofactor for RNA Polymerase II Transcription

(2017) Tiago Baptista et al.   MOLECULAR CELL

Transcription of Nearly All Yeast RNA Polymerase II-Transcribed Genes Is Dependent on Transcription Factor TFIID

(2017) Linda Warfield et al.   MOLECULAR CELL

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

UCSF ChimeraX: Meeting modern challenges in visualization and analysis

(2017) Thomas D. Goddard et al.   PROTEIN SCIENCE

Sharing the SAGA

(2017) Dominique Helmlinger et al.   TRENDS IN BIOCHEMICAL SCIENCES

Structure of the transcription activator target Tra1 within the chromatin modifying complex SAGA

(2017) Grigory Sharov et al.   Nature Communications

Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID

(2017) Kapil Gupta et al.   eLife

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Affinity and competition for TBP are molecular determinants of gene expression noise

(2016) Charles N. J. Ravarani et al.   Nature Communications

Conformational Flexibility and Subunit Arrangement of the Modular Yeast Spt-Ada-Gcn5 Acetyltransferase Complex

(2015) Dheva Setiaputra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis of transcription initiation by RNA polymerase II

(2015) Sarah Sainsbury et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

I-TASSER server: new development for protein structure and function predictions

(2015) Jianyi Yang et al.   NUCLEIC ACIDS RESEARCH

Architecture of the Saccharomyces cerevisiae SAGA transcription coactivator complex

(2014) Y. Han et al.   EMBO JOURNAL

The TAF9 C-Terminal Conserved Region Domain Is Required for SAGA and TFIID Promoter Occupancy To Promote Transcriptional Activation

(2014) M. Saint et al.   MOLECULAR AND CELLULAR BIOLOGY

C-terminus of the Sgf73 subunit of SAGA and SLIK is important for retention in the larger complex and for heterochromatin boundary function

(2013) Kazuma Kamata et al.   GENES TO CELLS

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

High-resolution structure of TBP with TAF1 reveals anchoring patterns in transcriptional regulation

(2013) Madhanagopal Anandapadamanaban et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Scalable web services for the PSIPRED Protein Analysis Workbench

(2013) Daniel W. A. Buchan et al.   NUCLEIC ACIDS RESEARCH

Template-based protein structure modeling using the RaptorX web server

(2012) Morten Källberg et al.   Nature Protocols

Transcriptional Regulation inSaccharomyces cerevisiae: Transcription Factor Regulation and Function, Mechanisms of Initiation, and Roles of Activators and Coactivators

(2011) Steven Hahn et al.   GENETICS

Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes

(2011) K. K. Lee et al.   Molecular Systems Biology

Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP

(2011) Petra Wollmann et al.   NATURE

Rapid model building of α-helices in electron-density maps

(2010) Thomas C. Terwilliger   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural Basis for Assembly and Activation of the Heterotetrameric SAGA Histone H2B Deubiquitinase Module

(2010) Alwin Köhler et al.   CELL

Structural Insights into the Assembly and Function of the SAGA Deubiquitinating Module

(2010) N. L. Samara et al.   SCIENCE

Site-specific cross-linking of TBP in vivo and in vitro reveals a direct functional interaction with the SAGA subunit Spt3

(2008) N. Mohibullah et al.   GENES & DEVELOPMENT

Characterization of new Spt3 and TBP mutants of Saccharomyces cerevisiae: Spt3-TBP allele-specific interactions and bypass of Spt8

(2007) L. Laprade et al.   GENETICS