Structure of human TFIID and mechanism of TBP loading onto promoter DNA

Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex

(2018) Lisa M. Tuttle et al.   Cell Reports

Real-space refinement in PHENIX for cryo-EM and crystallography

(2018) Pavel V. Afonine et al.   Acta Crystallographica Section D-Structural Biology

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Identification of heteromolecular binding sites in transcription factors Sp1 and TAF4 using high-resolution nuclear magnetic resonance spectroscopy

(2017) Emi Hibino et al.   PROTEIN SCIENCE

Sharing the SAGA

(2017) Dominique Helmlinger et al.   TRENDS IN BIOCHEMICAL SCIENCES

Structure of the transcription activator target Tra1 within the chromatin modifying complex SAGA

(2017) Grigory Sharov et al.   Nature Communications

Measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy

(2017) Katerina Naydenova et al.   Nature Communications

Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID

(2017) Kapil Gupta et al.   eLife

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Near-atomic resolution visualization of human transcription promoter opening

(2016) Yuan He et al.   NATURE

Structure of promoter-bound TFIID and model of human pre-initiation complex assembly

(2016) Robert K. Louder et al.   NATURE

Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2

(2016) Dari Kimanius et al.   eLife

Xlink Analyzer: Software for analysis and visualization of cross-linking data in the context of three-dimensional structures

(2015) Jan Kosinski et al.   JOURNAL OF STRUCTURAL BIOLOGY

xiNET: Cross-link Network Maps With Residue Resolution

(2015) Colin W. Combe et al.   MOLECULAR & CELLULAR PROTEOMICS

Cytoplasmic TAF2–TAF8–TAF10 complex provides evidence for nuclear holo–TFIID assembly from preformed submodules

(2015) Simon Trowitzsch et al.   Nature Communications

Looping Back to Leap Forward: Transcription Enters a New Era

(2014) Michael Levine et al.   CELL

Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module

(2014) Hui Wang et al.   CELL RESEARCH

Architecture of the Saccharomyces cerevisiae SAGA transcription coactivator complex

(2014) Y. Han et al.   EMBO JOURNAL

Structural and functional insight into TAF1-TAF7, a subcomplex of transcription factor II D

(2014) S. Bhattacharya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human TFIID Binds to Core Promoter DNA in a Reorganized Structural State

(2013) Michael A. Cianfrocco et al.   CELL

Direct TFIIA-TFIID Protein Contacts Drive Budding Yeast Ribosomal Protein Gene Transcription

(2013) Justin H. Layer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

iMODFIT: Efficient and robust flexible fitting based on vibrational analysis in internal coordinates

(2013) José Ramón Lopéz-Blanco et al.   JOURNAL OF STRUCTURAL BIOLOGY

The architecture of human general transcription factor TFIID core complex

(2013) Christoph Bieniossek et al.   NATURE

Structural visualization of key steps in human transcription initiation

(2013) Yuan He et al.   NATURE

High-resolution structure of TBP with TAF1 reveals anchoring patterns in transcriptional regulation

(2013) Madhanagopal Anandapadamanaban et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Scalable web services for the PSIPRED Protein Analysis Workbench

(2013) Daniel W. A. Buchan et al.   NUCLEIC ACIDS RESEARCH

Structural bioinformatics of the general transcription factor TFIID

(2012) Maja Malkowska et al.   BIOCHIMIE

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Prevention of overfitting in cryo-EM structure determination

(2012) Sjors H W Scheres et al.   NATURE METHODS

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural Basis for Acetylated Histone H4 Recognition by the Human BRD2 Bromodomain

(2010) Takashi Umehara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RNA Polymerase II and TAFs Undergo a Slow Isomerization after the Polymerase Is Recruited to Promoter-Bound TFIID

(2010) Petro Yakovchuk et al.   JOURNAL OF MOLECULAR BIOLOGY

ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids

(2010) H. Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

Fast signals and slow marks: the dynamics of histone modifications

(2010) Teresa K. Barth et al.   TRENDS IN BIOCHEMICAL SCIENCES

Structures of three distinct activator-TFIID complexes

(2009) W.-L. Liu et al.   GENES & DEVELOPMENT

TAF4/4b·TAF12 Displays a Unique Mode of DNA Binding and Is Required for Core Promoter Function of a Subset of Genes

(2009) Kfir Gazit et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Appion: An integrated, database-driven pipeline to facilitate EM image processing

(2009) Gabriel C. Lander et al.   JOURNAL OF STRUCTURAL BIOLOGY

Dynamic Regulation of Nucleosome Positioning in the Human Genome

(2008) Dustin E. Schones et al.   CELL

Nucleosome organization in the Drosophila genome

(2008) Travis N. Mavrich et al.   NATURE

TFIID component TAF7 functionally interacts with both TFIIH and P-TEFb

(2008) A. Gegonne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Insight into the Recognition of the H3K4me3 Mark by the TFIID Subunit TAF3

(2008) Hugo van Ingen et al.   STRUCTURE