Generating microglia from human pluripotent stem cells: novel in vitro models for the study of neurodegeneration
出版年份 2019 全文链接
标题
Generating microglia from human pluripotent stem cells: novel in vitro models for the study of neurodegeneration
作者
关键词
-
出版物
Molecular Neurodegeneration
Volume 14, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-12-19
DOI
10.1186/s13024-019-0347-z
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo
- (2019) Jonathan Hasselmann et al. NEURON
- Niche signals and transcription factors involved in tissue-resident macrophage development
- (2018) Wouter T'Jonck et al. CELLULAR IMMUNOLOGY
- A Combination of Ontogeny and CNS Environment Establishes Microglial Identity
- (2018) F. Chris Bennett et al. NEURON
- APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types
- (2018) Yuan-Ta Lin et al. NEURON
- Human induced pluripotent stem cell-derived glial cells and neural progenitors display divergent responses to Zika and dengue infections
- (2018) Julien Muffat et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional Studies of Missense TREM2 Mutations in Human Stem Cell-Derived Microglia
- (2018) Philip W. Brownjohn et al. Stem Cell Reports
- Aging in a Dish: iPSC-Derived and Directly Induced Neurons for Studying Brain Aging and Age-Related Neurodegenerative Diseases
- (2018) Jerome Mertens et al. Annual Review of Genetics
- The Trem2 R47H Alzheimer’s risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans
- (2018) Xianyuan Xiang et al. Molecular Neurodegeneration
- Microglial signatures and their role in health and disease
- (2018) Oleg Butovsky et al. NATURE REVIEWS NEUROSCIENCE
- Human Induced Pluripotent Stem Cell-Derived Microglia-Like Cells Harboring TREM2 Missense Mutations Show Specific Deficits in Phagocytosis
- (2018) Pablo Garcia-Reitboeck et al. Cell Reports
- Human stem cell–derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2
- (2018) Christel Claes et al. Alzheimers & Dementia
- Pathological Changes in Alzheimer’s Disease Analyzed Using Induced Pluripotent Stem Cell-Derived Human Microglia-Like Cells
- (2018) Mei Xu et al. JOURNAL OF ALZHEIMERS DISEASE
- Development and validation of a simplified method to generate human microglia from pluripotent stem cells
- (2018) Amanda McQuade et al. Molecular Neurodegeneration
- Microglia innately develop within cerebral organoids
- (2018) Paul R. Ormel et al. Nature Communications
- Hemangioblast, hemogenic endothelium, and primitive versus definitive hematopoiesis
- (2017) Georges Lacaud et al. EXPERIMENTAL HEMATOLOGY
- Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function
- (2017) Kazuyuki Takata et al. IMMUNITY
- Transcriptomic analysis of purified human cortical microglia reveals age-associated changes
- (2017) Thais F Galatro et al. NATURE NEUROSCIENCE
- Differentiation of human and murine induced pluripotent stem cells to microglia-like cells
- (2017) Hetal Pandya et al. NATURE NEUROSCIENCE
- iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases
- (2017) Edsel M. Abud et al. NEURON
- Elucidating the Role of TREM2 in Alzheimer’s Disease
- (2017) Jason D. Ulrich et al. NEURON
- An environment-dependent transcriptional network specifies human microglia identity
- (2017) David Gosselin et al. SCIENCE
- The Lifespan and Turnover of Microglia in the Human Brain
- (2017) Pedro Réu et al. Cell Reports
- Human Induced Pluripotent Stem Cell-Derived Macrophages Share Ontogeny with MYB -Independent Tissue-Resident Macrophages
- (2017) Julian Buchrieser et al. Stem Cell Reports
- Directed Differentiation of Human Pluripotent Stem Cells to Microglia
- (2017) Panagiotis Douvaras et al. Stem Cell Reports
- A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response
- (2017) Walther Haenseler et al. Stem Cell Reports
- Isolation of primary microglia from the human post-mortem brain: effects of ante- and post-mortem variables
- (2017) Mark R. Mizee et al. Acta Neuropathologica Communications
- Genetic variations underlying Alzheimer's disease: evidence from genome-wide association studies and beyond
- (2016) Elise Cuyvers et al. LANCET NEUROLOGY
- Molecular control of activation and priming in macrophages
- (2016) Christopher K Glass et al. NATURE IMMUNOLOGY
- Efficient derivation of microglia-like cells from human pluripotent stem cells
- (2016) Julien Muffat et al. NATURE MEDICINE
- A view of human haematopoietic development from the Petri dish
- (2016) Andrea Ditadi et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- TREM2 variants: new keys to decipher Alzheimer disease pathogenesis
- (2016) Marco Colonna et al. NATURE REVIEWS NEUROSCIENCE
- New tools for studying microglia in the mouse and human CNS
- (2016) Mariko L. Bennett et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microglial M1/M2 polarization and metabolic states
- (2015) Ruben Orihuela et al. BRITISH JOURNAL OF PHARMACOLOGY
- Early hematopoiesis and macrophage development
- (2015) Kathleen E. McGrath et al. SEMINARS IN IMMUNOLOGY
- Microglia in Health and Disease
- (2015) Richard M. Ransohoff et al. Cold Spring Harbor Perspectives in Biology
- Microglia Function in Central Nervous System Development and Plasticity
- (2015) Dorothy P. Schafer et al. Cold Spring Harbor Perspectives in Biology
- Distinct Sources of Hematopoietic Progenitors Emerge before HSCs and Provide Functional Blood Cells in the Mammalian Embryo
- (2015) Kathleen E. McGrath et al. Cell Reports
- Ontogeny of Tissue-Resident Macrophages
- (2015) Guillaume Hoeffel et al. Frontiers in Immunology
- NANOG and CDX2 Pattern Distinct Subtypes of Human Mesoderm during Exit from Pluripotency
- (2014) Sasha Mendjan et al. Cell Stem Cell
- Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
- (2014) Elisa Gomez Perdiguero et al. NATURE
- Wnt signaling controls the specification of definitive and primitive hematopoiesis from human pluripotent stem cells
- (2014) Christopher M Sturgeon et al. NATURE BIOTECHNOLOGY
- The human side of microglia
- (2014) Amy M. Smith et al. TRENDS IN NEUROSCIENCES
- Direct induction of ramified microglia-like cells from human monocytes: Dynamic microglial dysfunction in Nasu-Hakola disease
- (2014) Masahiro Ohgidani et al. Scientific Reports
- Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging
- (2013) Justine D. Miller et al. Cell Stem Cell
- Robust and Highly-Efficient Differentiation of Functional Monocytic Cells from Human Pluripotent Stem Cells under Serum- and Feeder Cell-Free Conditions
- (2013) Masakatsu D. Yanagimachi et al. PLoS One
- Efficient, Long Term Production of Monocyte-Derived Macrophages from Human Pluripotent Stem Cells under Partly-Defined and Fully-Defined Conditions
- (2013) Bonnie van Wilgenburg et al. PLoS One
- Comparison of polarization properties of human adult microglia and blood-derived macrophages
- (2012) Bryce A. Durafourt et al. GLIA
- Phenotyping primary human microglia: Tight regulation of LPS responsiveness
- (2012) Jeroen Melief et al. GLIA
- A novel in vitro human microglia model: Characterization of human monocyte-derived microglia
- (2012) Samar Etemad et al. JOURNAL OF NEUROSCIENCE METHODS
- Physiology of Microglia
- (2011) Helmut Kettenmann et al. PHYSIOLOGICAL REVIEWS
- Identification and Characterization of Enhancers Controlling the Inflammatory Gene Expression Program in Macrophages
- (2010) Serena Ghisletti et al. IMMUNITY
- Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
- (2010) Sven Heinz et al. MOLECULAR CELL
- Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
- (2010) F. Ginhoux et al. SCIENCE
- Homogeneous monocytes and macrophages from human embryonic stem cells following coculture-free differentiation in M-CSF and IL-3
- (2008) Karl R. Karlsson et al. EXPERIMENTAL HEMATOLOGY
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