The plant N‐degron pathways of ubiquitin‐mediated proteolysis

Endogenous hypoxia in lateral root primordia controls root architecture by antagonizing auxin signaling in Arabidopsis

(2019) Vinay Shukla et al.   Molecular Plant

N-degron and C-degron pathways of protein degradation

(2019) Alexander Varshavsky   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxic Conditions in Crown Galls Induce Plant Anaerobic Responses That Support Tumor Proliferation

(2019) Lucy Kerpen et al.   Frontiers in Plant Science

N-terminal degradation activates the NLRP1B inflammasome

(2019) Ashley J. Chui et al.   SCIENCE

Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes

(2019) Andrew Sandstrom et al.   SCIENCE

Regulatory cascade involving transcriptional and N-end rule pathways in rice under submergence

(2019) Chih-Cheng Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulating Protein Stability to Switch Toxic Protein Function On and Off in Living Cells

(2019) Frederik Faden et al.   PLANT PHYSIOLOGY

Tandem fluorescent protein timers for non-invasive relative protein lifetime measurement in plants

(2019) Hongtao Zhang et al.   PLANT PHYSIOLOGY

New beginnings and new ends: methods for large-scale characterization of protein termini and their use in plant biology

(2019) Andreas Perrar et al.   JOURNAL OF EXPERIMENTAL BOTANY

N-terminal methionine excision of proteins creates tertiary destabilizing N-degrons of the Arg/N-end rule pathway

(2019) Kha The Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Scope, Functions, and Dynamics of Posttranslational Protein Modifications

(2019) A. Harvey Millar et al.   Annual Review of Plant Biology

N‐degron specificity of chloroplast ClpS1 in plants

(2019) Cyrille Montandon et al.   FEBS LETTERS

A Ratiometric Sensor Based on Plant N-Terminal Degrons Able to Report Oxygen Dynamics in Saccharomyces cerevisiae

(2019) Mikel Lavilla Puerta et al.   JOURNAL OF MOLECULAR BIOLOGY

An apical hypoxic niche sets the pace of shoot meristem activity

(2019) Daan A. Weits et al.   NATURE

Zinc excess induces a hypoxia-like response by inhibiting cysteine oxidases in poplar roots

(2019) Laura Dalle Carbonare et al.   PLANT PHYSIOLOGY

Discovery of a Nitric Oxide-Responsive Protein in Arabidopsis thaliana

(2019) Randa Zarban et al.   MOLECULES

Differential N-end Rule Degradation of RIN4/NOI Fragments Generated by the AvrRpt2 Effector Protease

(2019) Kevin Goslin et al.   PLANT PHYSIOLOGY

A glycine-specific N-degron pathway mediates the quality control of protein N-myristoylation

(2019) Richard T. Timms et al.   SCIENCE

Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants

(2019) Norma Masson et al.   SCIENCE

At ERF #111/ ABR 1 is a transcriptional activator involved in the wounding response

(2019) Judith Bäumler et al.   PLANT JOURNAL

Ethylene-mediated nitric oxide depletion pre-adapts plants to hypoxia stress

(2019) Sjon Hartman et al.   Nature Communications

The Eukaryotic Proteome Is Shaped by E3 Ubiquitin Ligases Targeting C-Terminal Degrons

(2018) Itay Koren et al.   CELL

Can genomics deliver climate-change ready crops?

(2018) Rajeev K Varshney et al.   CURRENT OPINION IN PLANT BIOLOGY

Energy-crises in well-aerated and anoxic tissue: does tolerance require the same specific proteins and energy-efficient transport?

(2018) Hank Greenway et al.   FUNCTIONAL PLANT BIOLOGY

The Plant Cysteine Oxidases fromArabidopsis thalianaare kinetically tailored to act as oxygen sensors

(2018) Mark D. White et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mapping Degradation Signals and Pathways in a Eukaryotic N-terminome

(2018) Ilia Kats et al.   MOLECULAR CELL

C-Terminal End-Directed Protein Elimination by CRL2 Ubiquitin Ligases

(2018) Hsiu-Chuan Lin et al.   MOLECULAR CELL

A Gatekeeper Residue of ClpS1 from Arabidopsis thaliana Chloroplasts Determines its Affinity Towards Substrates of the Bacterial N-End Rule

(2018) Clara V Colombo et al.   PLANT AND CELL PHYSIOLOGY

Distinct branches of the N-end rule pathway modulate the plant immune response

(2018) Jorge Vicente et al.   NEW PHYTOLOGIST

Genetic interactions between ABA signalling and the Arg/N-end rule pathway during Arabidopsis seedling establishment

(2018) Hongtao Zhang et al.   Scientific Reports

Revisiting the Role of Ethylene and N-End Rule Pathway on Chilling-Induced Dormancy Release in Arabidopsis Seeds

(2018) Xu Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oxygen-dependent proteolysis regulates the stability of angiosperm polycomb repressive complex 2 subunit VERNALIZATION 2

(2018) Daniel J. Gibbs et al.   Nature Communications

Ubiquitylation activates a peptidase that promotes cleavage and destabilization of its activating E3 ligases and diverse growth regulatory proteins to limit cell proliferation inArabidopsis

(2017) Hui Dong et al.   GENES & DEVELOPMENT

Real-time detection of N-end rule-mediated ubiquitination via fluorescently labeled substrate probes

(2017) Augustin C. Mot et al.   NEW PHYTOLOGIST

Cutting in the middleman: hidden substrates at the interface between proteases and plant development

(2017) Chen Liu et al.   NEW PHYTOLOGIST

N-terminomics reveals control of Arabidopsis seed storage proteins and proteases by the Arg/N-end rule pathway

(2017) Hongtao Zhang et al.   NEW PHYTOLOGIST

Age-dependent regulation of ERF-VII transcription factor activity in Arabidopsis thaliana

(2017) Beatrice Giuntoli et al.   PLANT CELL AND ENVIRONMENT

Plant cysteine oxidases are dioxygenases that directly enable arginyl transferase-catalysed arginylation of N-end rule targets

(2017) Mark D. White et al.   Nature Communications

p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis

(2017) Hyunjoo Cha-Molstad et al.   Nature Communications

Hypoxia response in Arabidopsis roots infected by Plasmodiophora brassicae supports the development of clubroot

(2016) Antoine Gravot et al.   BMC PLANT BIOLOGY

Identification of Targets and Interaction Partners of Arginyl-tRNA Protein Transferase in the MossPhyscomitrella patens

(2016) Sebastian N. W. Hoernstein et al.   MOLECULAR & CELLULAR PROTEOMICS

From start to finish: amino-terminal protein modifications as degradation signals in plants

(2016) Daniel J. Gibbs et al.   NEW PHYTOLOGIST

Phenotypes on demand via switchable target protein degradation in multicellular organisms

(2016) Frederik Faden et al.   Nature Communications

The N-end rule pathway regulates pathogen responses in plants

(2016) Rémi de Marchi et al.   Scientific Reports

Autophagy contributes to regulation of the hypoxia response during submergence inArabidopsis thaliana

(2015) Liang Chen et al.   Autophagy

Organization, function and substrates of the essential Clp protease system in plastids

(2015) Kenji Nishimura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Oxygen Sensing Coordinates Photomorphogenesis to Facilitate Seedling Survival

(2015) Mohamad Abbas et al.   CURRENT BIOLOGY

Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding

(2015) Hyunjoo Cha-Molstad et al.   NATURE CELL BIOLOGY

Spatio-temporal patterning of arginyl-tRNA protein transferase (ATE) contributes to gametophytic development in a moss

(2015) Christian Schuessele et al.   NEW PHYTOLOGIST

Enhanced waterlogging tolerance in barley by manipulation of expression of the N-end rule pathway E3 ligase PROTEOLYSIS6

(2015) Guillermina M. Mendiondo et al.   PLANT BIOTECHNOLOGY JOURNAL

Two N-Terminal Acetyltransferases Antagonistically Regulate the Stability of a Nod-Like Receptor in Arabidopsis

(2015) Fang Xu et al.   PLANT CELL

The stability and nuclear localization of the transcription factor RAP2.12 are dynamically regulated by oxygen concentration

(2015) MONIKA KOSMACZ et al.   PLANT CELL AND ENVIRONMENT

TheGreening after Extended Darkness1Is an N-End Rule Pathway Mutant with High Tolerance to Submergence and Starvation

(2015) Willi Riber et al.   PLANT PHYSIOLOGY

Group VII Ethylene Response Factors Coordinate Oxygen and Nitric Oxide Signal Transduction and Stress Responses in Plants

(2015) Daniel J. Gibbs et al.   PLANT PHYSIOLOGY

Generic tools for conditionally altering protein abundance and phenotypes on demand

(2014) Frederik Faden et al.   BIOLOGICAL CHEMISTRY

Nitric Oxide Sensing in Plants Is Mediated by Proteolytic Control of Group VII ERF Transcription Factors

(2014) Daniel J. Gibbs et al.   MOLECULAR CELL

The Putative E3 Ubiquitin Ligase ECERIFERUM9 Regulates Abscisic Acid Biosynthesis and Response during Seed Germination and Postgermination Growth in Arabidopsis

(2014) H. Zhao et al.   PLANT PHYSIOLOGY

Large-Scale Identification of Gibberellin-Related Transcription Factors Defines Group VII ETHYLENE RESPONSE FACTORS as Functional DELLA Partners

(2014) N. M.-d. la Rosa et al.   PLANT PHYSIOLOGY

The eukaryotic N-end rule pathway: conserved mechanisms and diverse functions

(2014) Daniel J. Gibbs et al.   TRENDS IN CELL BIOLOGY

Plant cysteine oxidases control the oxygen-dependent branch of the N-end-rule pathway

(2014) Daan A. Weits et al.   Nature Communications

Control of Protein Quality and Stoichiometries by N-Terminal Acetylation and the N-End Rule Pathway

(2013) Anna Shemorry et al.   MOLECULAR CELL

Neurodegeneration-Associated Protein Fragments as Short-Lived Substrates of the N-End Rule Pathway

(2013) Christopher S. Brower et al.   MOLECULAR CELL

The Arabidopsis METACASPASE9 Degradome

(2013) L. Tsiatsiani et al.   PLANT CELL

The Ubiquitin Receptor DA1 Interacts with the E3 Ubiquitin Ligase DA2 to Regulate Seed and Organ Size in Arabidopsis

(2013) T. Xia et al.   PLANT CELL

Differential growth at the apical hook: all roads lead to auxin

(2013) Mohamad Abbas et al.   Frontiers in Plant Science

The N-End Rule Pathway

(2012) Takafumi Tasaki et al.   Annual Review of Biochemistry

Autophagy: Pathways for Self-Eating in Plant Cells

(2012) Yimo Liu et al.   Annual Review of Plant Biology

Characterization of Arginylation Branch of N-end Rule Pathway in G-protein-mediated Proliferation and Signaling of Cardiomyocytes

(2012) Min Jae Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments

(2012) K. I. Piatkov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia Triggers Meiotic Fate Acquisition in Maize

(2012) T. Kelliher et al.   SCIENCE

Making sense of low oxygen sensing

(2012) Julia Bailey-Serres et al.   TRENDS IN PLANT SCIENCE

Oxygen sensing in plants is mediated by an N-end rule pathway for protein destabilization

(2011) Francesco Licausi et al.   NATURE

Homeostatic response to hypoxia is regulated by the N-end rule pathway in plants

(2011) Daniel J. Gibbs et al.   NATURE

Natural substrates of plant proteases: how can protease degradomics extend our knowledge?

(2011) Liana Tsiatsiani et al.   PHYSIOLOGIA PLANTARUM

Identification of protein stability determinants in chloroplasts

(2010) Wiebke Apel et al.   PLANT JOURNAL

Cross-Kingdom Comparison of Transcriptomic Adjustments to Low-Oxygen Stress Highlights Conserved and Plant-Specific Responses

(2010) A. Mustroph et al.   PLANT PHYSIOLOGY

N-Terminal Acetylation of Cellular Proteins Creates Specific Degradation Signals

(2010) C.-S. Hwang et al.   SCIENCE

Glutamine-Specific N-Terminal Amidase, a Component of the N-End Rule Pathway

(2009) Haiqing Wang et al.   MOLECULAR CELL

The ethylene response factors SNORKEL1 and SNORKEL2 allow rice to adapt to deep water

(2009) Yoko Hattori et al.   NATURE

Structure and evolutionary conservation of the plant N-end rule pathway

(2009) Emmanuelle Graciet et al.   PLANT JOURNAL

The N-end rule pathway promotes seed germination and establishment through removal of ABA sensitivity in Arabidopsis

(2009) T. J. Holman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The N-end rule pathway controls multiple functions during Arabidopsis shoot and leaf development

(2009) E. Graciet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA