Identification of sirtuin 1 as a promising therapeutic target for hypertrophic scars

Lifespan and healthspan extension by resveratrol

(2015) Khushwant S. Bhullar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Concise Guide to PHARMACOLOGY 2015/16: Enzymes

(2015) Stephen PH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Experimental design and analysis and their reporting: new guidance for publication in BJP

(2015) Michael J Curtis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Implementing guidelines on reporting research using animals (ARRIVE etc.): new requirements for publication in BJP

(2015) John C McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Targeting cardiac fibroblasts to treat fibrosis of the heart: Focus on HDACs

(2014) Katherine B. Schuetze et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Class I HDACs regulate angiotensin II-dependent cardiac fibrosis via fibroblasts and circulating fibrocytes

(2014) Sarah M. Williams et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

SIRT1 and other sirtuins in metabolism

(2014) Hung-Chun Chang et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Protection against TGF-β1-induced fibrosis effects of IL-10 on dermal fibroblasts and its potential therapeutics for the reduction of skin scarring

(2013) Ji-Hong Shi et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Sirtuin deacetylases in neurodegenerative diseases of aging

(2013) Adrianna Z Herskovits et al.   CELL RESEARCH

Role of sirtuins in kidney disease

(2013) Munehiro Kitada et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Sirt1 Activation Ameliorates Renal Fibrosis by Inhibiting the TGF-β/Smad3 Pathway

(2013) Xin-Zhong Huang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

PI3K p110γ overexpression in idiopathic pulmonary fibrosis lung tissue and fibroblast cells: in vitro effects of its inhibition

(2013) Enrico Conte et al.   LABORATORY INVESTIGATION

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

(2013) Adam J. Pawson et al.   NUCLEIC ACIDS RESEARCH

Histone Deacetylase Inhibitor Reduces Hypertrophic Scarring in a Rabbit Ear Model

(2013) Jian-Sheng Diao et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Resveratrol as a therapeutic agent for renal fibrosis induced by unilateral ureteral obstruction

(2013) Jin Liang et al.   RENAL FAILURE

Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators

(2013) B. P. Hubbard et al.   SCIENCE

Resveratrol inhibits fibrogenesis and induces apoptosis in keloid fibroblasts

(2013) Kanae Ikeda et al.   WOUND REPAIR AND REGENERATION

SIRT1 Suppresses the Epithelial-to-Mesenchymal Transition in Cancer Metastasis and Organ Fibrosis

(2013) Petra Simic et al.   Cell Reports

Critical Role of Transforming Growth Factor Beta in Different Phases of Wound Healing

(2013) Mohammadreza Pakyari et al.   Advances in Wound Care

SIRT1 in Type 2 Diabetes: Mechanisms and Therapeutic Potential

(2013) Munehiro Kitada et al.   Diabetes & Metabolism Journal

SIRT1 deacetylates RFX5 and antagonizes repression of collagen type I (COL1A2) transcription in smooth muscle cells

(2012) Jun Xia et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Multiple roles of class I HDACs in proliferation, differentiation, and development

(2012) Nina Reichert et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Effect of Resveratrol on Treatment of Bleomycin-Induced Pulmonary Fibrosis in Rats

(2012) Recep Akgedik et al.   INFLAMMATION

The myofibroblast matrix: implications for tissue repair and fibrosis

(2012) Franco Klingberg et al.   JOURNAL OF PATHOLOGY

Effects of resveratrol on incisional wound healing in rats

(2012) Ismail Yaman et al.   SURGERY TODAY

A systematic review of the quality of burn scar rating scales for clinical and research use

(2011) Zephanie Tyack et al.   BURNS

Cutaneous scarring: Pathophysiology, molecular mechanisms, and scar reduction therapeutics

(2011) Christos Profyris et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Extracellular matrix molecules implicated in hypertrophic and keloid scarring

(2011) G.P. Sidgwick et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

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(2011) Gerd Gauglitz et al.   MOLECULAR MEDICINE

Inhibition of PI3K Prevents the Proliferation and Differentiation of Human Lung Fibroblasts into Myofibroblasts: The Role of Class I P110 Isoforms

(2011) Enrico Conte et al.   PLoS One

Histone deacetylases as regulators of inflammation and immunity

(2011) Melanie R. Shakespear et al.   TRENDS IN IMMUNOLOGY

Mechanisms of pathological scarring: Role of myofibroblasts and current developments

(2011) Vincent Sarrazy et al.   WOUND REPAIR AND REGENERATION

Resveratrol attenuates apoptosis of pulmonary microvascular endothelial cells induced by high shear stress and proinflammatory factors

(2011) Liang Xia et al.   Human Cell

Resveratrol Inhibits Renal Fibrosis in the Obstructed Kidney

(2010) Jinhua Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Suppression of TGF-β1/SMAD pathway and extracellular matrix production in primary keloid fibroblasts by curcuminoids: its potential therapeutic use in the chemoprevention of keloid

(2010) Yi-Chiang Hsu et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Resveratrol inhibits dimethylnitrosamine-induced hepatic fibrosis in rats

(2010) Eun-Sil Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

SIRT1 regulates oxidant- and cigarette smoke-induced eNOS acetylation in endothelial cells: Role of resveratrol

(2010) Gnanapragasam Arunachalam et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Sirt1 acts in association with PPAR  to protect the heart from hypertrophy, metabolic dysregulation, and inflammation

(2010) A. Planavila et al.   CARDIOVASCULAR RESEARCH

EDA-containing cellular fibronectin induces fibroblast differentiation through binding to α4β7 integrin receptor and MAPK/Erk 1/2-dependent signaling

(2010) Martin Kohan et al.   FASEB JOURNAL

Notch1 Deficiency Results in Decreased Inflammation during Wound Healing and Regulates Vascular Endothelial Growth Factor Receptor-1 and Inflammatory Cytokine Expression in Macrophages

(2010) H. Hamilton Outtz et al.   JOURNAL OF IMMUNOLOGY

The myofibroblast: Paradigm for a mechanically active cell

(2009) Boris Hinz   JOURNAL OF BIOMECHANICS

Is There an Ideal Animal Model to Study Hypertrophic Scarring?

(2009) Maria Luiza Christovão Ramos et al.   Journal of Burn Care & Research

SIRT1 Transcription Is Decreased in Visceral Adipose Tissue of Morbidly Obese Patients with Severe Hepatic Steatosis

(2009) Cíntia dos Santos Costa et al.   OBESITY SURGERY

Potential cellular and molecular causes of hypertrophic scar formation

(2008) Willem M. van der Veer et al.   BURNS

Histone-deacetylase inhibition reverses atrial arrhythmia inducibility and fibrosis in cardiac hypertrophy independent of angiotensin

(2008) Fang Liu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Wound repair and regeneration

(2008) Geoffrey C. Gurtner et al.   NATURE