HELLS and PRDM9 form a pioneer complex to open chromatin at meiotic recombination hot spots

Factors influencing meiotic recombination revealed by whole-genome sequencing of single sperm

(2019) Anjali Gupta Hinch et al.   SCIENCE

Dynamic reorganization of the genome shapes the recombination landscape in meiotic prophase

(2019) Lucas Patel et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Histone methyltransferase PRDM9 is not essential for meiosis in male mice

(2019) Ondrej Mihola et al.   GENOME RESEARCH

Unified single-cell analysis of testis gene regulation and pathology in five mouse strains

(2019) Min Jung et al.   eLife

The histone modification reader ZCWPW1 is required for meiosis prophase I in male but not in female mice

(2019) Miao Li et al.   Science Advances

Cell-type-specific genomics reveals histone modification dynamics in mammalian meiosis

(2019) Kwan-Wood Gabriel Lam et al.   Nature Communications

Hierarchical analysis of RNA-seq reads improves the accuracy of allele-specific expression

(2018) Narayanan Raghupathy et al.   BIOINFORMATICS

ATACseqQC: a Bioconductor package for post-alignment quality assessment of ATAC-seq data

(2018) Jianhong Ou et al.   BMC GENOMICS

PRDM9 Methyltransferase Activity Is Essential for Meiotic DNA Double-Strand Break Formation at Its Binding Sites

(2018) Boubou Diagouraga et al.   MOLECULAR CELL

HELLS and CDCA7 comprise a bipartite nucleosome remodeling complex defective in ICF syndrome

(2018) Christopher Jenness et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tissue-Specific Trans Regulation of the Mouse Epigenome

(2018) Christopher L. Baker et al.   GENETICS

Aberrant PRDM9 expression impacts the pan-cancer genomic landscape

(2018) Armande Ang Houle et al.   GENOME RESEARCH

Hotspots for Initiation of Meiotic Recombination

(2018) Andrew J. Tock et al.   Frontiers in Genetics

In vivo binding of PRDM9 reveals interactions with noncanonical genomic sites

(2017) Corinne Grey et al.   GENOME RESEARCH

PRDM9 interactions with other proteins provide a link between recombination hotspots and the chromosomal axis in meiosis

(2017) Emil D. Parvanov et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes

(2017) Cedric R. Clapier et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The histone variant H2A.Z promotes initiation of meiotic recombination in fission yeast

(2017) Shintaro Yamada et al.   NUCLEIC ACIDS RESEARCH

Dynamic reorganization of open chromatin underlies diverse transcriptomes during spermatogenesis

(2017) So Maezawa et al.   NUCLEIC ACIDS RESEARCH

The pioneer factor OCT4 requires the chromatin remodeller BRG1 to support gene regulatory element function in mouse embryonic stem cells

(2017) Hamish W King et al.   eLife

The Mouse INO80 Chromatin-Remodeling Complex Is an Essential Meiotic Factor for Spermatogenesis1

(2016) Daniel W. Serber et al.   BIOLOGY OF REPRODUCTION

Regulatory complexity revealed by integrated cytological and RNA-seq analyses of meiotic substages in mouse spermatocytes

(2016) Robyn L. Ball et al.   BMC GENOMICS

Steroid Receptors Reprogram FoxA1 Occupancy through Dynamic Chromatin Transitions

(2016) Erin E. Swinstead et al.   CELL

The Landscape of Mouse Meiotic Double-Strand Break Formation, Processing, and Repair

(2016) Julian Lange et al.   CELL

Pioneer transcription factors, chromatin dynamics, and cell fate control

(2016) Kenneth S Zaret et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The evolutionary turnover of recombination hot spots contributes to speciation in mice

(2016) Fatima Smagulova et al.   GENES & DEVELOPMENT

Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution

(2016) M Ryan Corces et al.   NATURE GENETICS

The SNF2 family ATPase LSH promotes cell-autonomousde novoDNA methylation in somatic cells

(2016) Ausma Termanis et al.   NUCLEIC ACIDS RESEARCH

Nuclear localization of PRDM9 and its role in meiotic chromatin modifications and homologous synapsis

(2015) Fengyun Sun et al.   CHROMOSOMA

The ATP binding site of the chromatin remodeling homolog Lsh is required for nucleosome density and de novo DNA methylation at repeat sequences

(2015) Jianke Ren et al.   NUCLEIC ACIDS RESEARCH

Affinity-seq detects genome-wide PRDM9 binding sites and reveals the impact of prior chromatin modifications on mammalian recombination hotspot usage

(2015) Michael Walker et al.   Epigenetics & Chromatin

Mutations in CDCA7 and HELLS cause immunodeficiency–centromeric instability–facial anomalies syndrome

(2015) Peter E. Thijssen et al.   Nature Communications

PRDM9 Drives Evolutionary Erosion of Hotspots in Mus musculus through Haplotype-Specific Initiation of Meiotic Recombination

(2015) Christopher L. Baker et al.   PLoS Genetics

Multimer Formation Explains Allelic Suppression of PRDM9 Recombination Hotspots

(2015) Christopher L. Baker et al.   PLoS Genetics

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Prdm9 Polymorphism Unveils Mouse Evolutionary Tracks

(2014) H. Kono et al.   DNA RESEARCH

Pioneer transcription factors in cell reprogramming

(2014) Makiko Iwafuchi-Doi et al.   GENES & DEVELOPMENT

Genome-wide DNA methylation patterns in LSH mutant reveals de-repression of repeat elements and redundant epigenetic silencing pathways

(2014) Weishi Yu et al.   GENOME RESEARCH

PRDM9 binding organizes hotspot nucleosomes and limits Holliday junction migration

(2014) C. L. Baker et al.   GENOME RESEARCH

UpSet: Visualization of Intersecting Sets

(2014) Alexander Lex et al.   IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS

Trimethylation of Histone H3 Lysine 36 by Human Methyltransferase PRDM9 Protein

(2014) Mohammad S. Eram et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNase Footprint Signatures Are Dictated by Factor Dynamics and DNA Sequence

(2014) Myong-Hee Sung et al.   MOLECULAR CELL

Chromatin Remodeling at DNA Double-Strand Breaks

(2013) Brendan D. Price et al.   CELL

Effect of natural genetic variation on enhancer selection and function

(2013) S. Heinz et al.   NATURE

Arabidopsis meiotic crossover hot spots overlap with H2A.Z nucleosomes at gene promoters

(2013) Kyuha Choi et al.   NATURE GENETICS

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

(2013) Jason D Buenrostro et al.   NATURE METHODS

Meiotic recombination in mammals: localization and regulation

(2013) Frédéric Baudat et al.   NATURE REVIEWS GENETICS

Facilitators and Impediments of the Pluripotency Reprogramming Factors' Initial Engagement with the Genome

(2012) Abdenour Soufi et al.   CELL

Sensitive mapping of recombination hotspots using sequencing-based detection of ssDNA

(2012) P. P. Khil et al.   GENOME RESEARCH

Constitutive nuclear lamina-genome interactions are highly conserved and associated with A/T-rich sequence

(2012) W. Meuleman et al.   GENOME RESEARCH

Genetic recombination is directed away from functional genomic elements in mice

(2012) Kevin Brick et al.   NATURE

A map of the cis-regulatory sequences in the mouse genome

(2012) Yin Shen et al.   NATURE

ChromHMM: automating chromatin-state discovery and characterization

(2012) Jason Ernst et al.   NATURE METHODS

Lymphoid-Specific Helicase (HELLS) Is Essential for Meiotic Progression in Mouse Spermatocytes1

(2011) Wenxian Zeng et al.   BIOLOGY OF REPRODUCTION

Global Regulation of H2A.Z Localization by the INO80 Chromatin-Remodeling Enzyme Is Essential for Genome Integrity

(2011) Manolis Papamichos-Chronakis et al.   CELL

The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation

(2011) Björn von Eyss et al.   EMBO JOURNAL

Genome-wide analysis reveals novel molecular features of mouse recombination hotspots

(2011) Fatima Smagulova et al.   NATURE

Variants of the protein PRDM9 differentially regulate a set of human meiotic recombination hotspots highly active in African populations

(2011) I. L. Berg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Anatomy of mouse recombination hot spots

(2010) Zhen K. Wu et al.   NUCLEIC ACIDS RESEARCH

Prdm9 Controls Activation of Mammalian Recombination Hotspots

(2010) E. D. Parvanov et al.   SCIENCE

Drive Against Hotspot Motifs in Primates Implicates the PRDM9 Gene in Meiotic Recombination

(2010) S. Myers et al.   SCIENCE

PRDM9 Is a Major Determinant of Meiotic Recombination Hotspots in Humans and Mice

(2010) F. Baudat et al.   SCIENCE

The Biology of Chromatin Remodeling Complexes

(2009) Cedric R. Clapier et al.   Annual Review of Biochemistry

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Distinct histone modifications define initiation and repair of meiotic recombination in the mouse

(2009) Jérôme Buard et al.   EMBO JOURNAL

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Cre recombinase activity specific to postnatal, premeiotic male germ cells in transgenic mice

(2008) Patricia I. Sadate-Ngatchou et al.   GENESIS

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY