Trimethylation of Histone H3 Lysine 36 by Human Methyltransferase PRDM9 Protein

Meta-analysis of clinical data using human meiotic genes identifies a novel cohort of highly restricted cancer-specific marker genes.

(2015) Julia Feichtinger et al.   Oncotarget

The Histone Mark H3K36me3 Regulates Human DNA Mismatch Repair through Its Interaction with MutSα

(2013) Feng Li et al.   CELL

Molecular Basis for the Regulation of the H3K4 Methyltransferase Activity of PRDM9

(2013) Hong Wu et al.   Cell Reports

Prdm3 and Prdm16 are H3K9me1 Methyltransferases Required for Mammalian Heterochromatin Integrity

(2012) Inês Pinheiro et al.   CELL

The Prdm family: expanding roles in stem cells and development

(2012) T. Hohenauer et al.   DEVELOPMENT

Rare allelic forms of PRDM9 associated with childhood leukemogenesis

(2012) J. Hussin et al.   GENOME RESEARCH

Sinefungin Derivatives as Inhibitors and Structure Probes of Protein Lysine Methyltransferase SETD2

(2012) Weihong Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inflammasomes in carcinogenesis and anticancer immune responses

(2012) Laurence Zitvogel et al.   NATURE IMMUNOLOGY

NSD2 Links Dimethylation of Histone H3 at Lysine 36 to Oncogenic Programming

(2011) Alex J. Kuo et al.   MOLECULAR CELL

Genome-wide analysis reveals novel molecular features of mouse recombination hotspots

(2011) Fatima Smagulova et al.   NATURE

The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

(2011) N. Stransky et al.   SCIENCE

Histone Methyltransferase Gene SETD2 Is a Novel Tumor Suppressor Gene in Clear Cell Renal Cell Carcinoma

(2010) Gerben Duns et al.   CANCER RESEARCH

Histone methyltransferases: regulation of transcription and contribution to human disease

(2010) Keisuke Nimura et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Fine-scale recombination rate differences between sexes, populations and individuals

(2010) Augustine Kong et al.   NATURE

Epigenetic modifications as therapeutic targets

(2010) Theresa K Kelly et al.   NATURE BIOTECHNOLOGY

PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans

(2010) Ingrid L Berg et al.   NATURE GENETICS

Mammalian recombination hot spots: properties, control and evolution

(2010) Kenneth Paigen et al.   NATURE REVIEWS GENETICS

PRDM9 Is a Major Determinant of Meiotic Recombination Hotspots in Humans and Mice

(2010) F. Baudat et al.   SCIENCE

Histone methyltransferase PRDM8 regulates mouse testis steroidogenesis

(2009) Gwang Hyeon Eom et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Distinct histone modifications define initiation and repair of meiotic recombination in the mouse

(2009) Jérôme Buard et al.   EMBO JOURNAL

Single-Nucleotide Polymorphisms of the PRDM9 (MEISETZ) Gene in Patients With Nonobstructive Azoospermia

(2009) S. Irie et al.   JOURNAL OF ANDROLOGY

The Target of the NSD Family of Histone Lysine Methyltransferases Depends on the Nature of the Substrate

(2009) Yan Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

On the Mechanism of Multiple Lysine Methylation by the Human Mixed Lineage Leukemia Protein-1 (MLL1) Core Complex

(2009) Anamika Patel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential chromatin marking of introns and expressed exons by H3K36me3

(2009) Paulina Kolasinska-Zwierz et al.   NATURE GENETICS

Histone methyltransferases in cancer

(2009) Mareike Albert et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Histone H3 lysine 4 trimethylation marks meiotic recombination initiation sites

(2008) Valérie Borde et al.   EMBO JOURNAL

Two single nucleotide polymorphisms in PRDM9 (MEISETZ) gene may be a genetic risk factor for Japanese patients with azoospermia by meiotic arrest

(2008) Toshinobu Miyamoto et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Histone H3K4me3 Binding Is Required for the DNA Repair and Apoptotic Activities of ING1 Tumor Suppressor

(2008) P.V. Peña et al.   JOURNAL OF MOLECULAR BIOLOGY

A common sequence motif associated with recombination hot spots and genome instability in humans

(2008) Simon Myers et al.   NATURE GENETICS

A Mouse Speciation Gene Encodes a Meiotic Histone H3 Methyltransferase

(2008) O. Mihola et al.   SCIENCE

PRDM6 is enriched in vascular precursors during development and inhibits endothelial cell proliferation, survival, and differentiation

(2007) Yaxu Wu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY