Aberrant lipid metabolism in hepatocellular carcinoma cells as well as immune microenvironment: A review
出版年份 2020 全文链接
标题
Aberrant lipid metabolism in hepatocellular carcinoma cells as well as immune microenvironment: A review
作者
关键词
-
出版物
CELL PROLIFERATION
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2020-01-31
DOI
10.1111/cpr.12772
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Aberrant lipid metabolism as a therapeutic target in liver cancer
- (2019) Evans D. Pope et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans
- (2019) Li Che et al. GUT
- Characterization of Lipid and Lipid Droplet Metabolism in Human HCC
- (2019) Berndt et al. Cells
- Non-viral nano-immunotherapeutics targeting tumor microenvironmental immune cells
- (2019) Seok-Beom Yong et al. BIOMATERIALS
- Investigation of lipid metabolism dysregulation and the effects on immune microenvironments in pan-cancer using multiple omics data
- (2019) Yang Hao et al. BMC BIOINFORMATICS
- Sphere-forming culture enriches liver cancer stem cells and reveals Stearoyl-CoA desaturase 1 as a potential therapeutic target
- (2019) Xiao-Lu Ma et al. BMC CANCER
- Intratumoral plasmacytoid dendritic cells as a poor prognostic factor for hepatocellular carcinoma following curative resection
- (2019) Zheng-Jun Zhou et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Macrophages and Metabolism in the Tumor Microenvironment
- (2019) Ilio Vitale et al. Cell Metabolism
- CXCR6 deficiency ameliorates ischemia-reperfusion injury by reducing the recruitment and cytokine production of hepatic NKT cells in a mouse model of non-alcoholic fatty liver disease
- (2019) Huanbing Zhu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- HBx combined with AFB1 triggers hepatic steatosis via COX‐2‐mediated necrosome formation and mitochondrial dynamics disorder
- (2019) Yuan‐Yuan Chen et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Metabolic flexibility in melanoma: A potential therapeutic target
- (2019) Maria Rosaria Ruocco et al. SEMINARS IN CANCER BIOLOGY
- Metabolic Control of Dendritic Cell Functions: Digesting Information
- (2019) Stefanie K. Wculek et al. Frontiers in Immunology
- Lipid metabolism and lipophagy in cancer
- (2018) Meenu Maan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Metabolic changes in tumor cells and tumor-associated macrophages: A mutual relationship
- (2018) Romana T. Netea-Maier et al. CANCER LETTERS
- Cancer Lipid Metabolism Confers Antiangiogenic Drug Resistance
- (2018) Hideki Iwamoto et al. Cell Metabolism
- CPT2 downregulation adapts HCC to lipid-rich environment and promotes carcinogenesis via acylcarnitine accumulation in obesity
- (2018) Naoto Fujiwara et al. GUT
- β-catenin-activated hepatocellular carcinomas are addicted to fatty acids
- (2018) Nadia Senni et al. GUT
- Macrophage plasticity, polarization, and function in health and disease
- (2018) Abbas Shapouri-Moghaddam et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Fatty acid oxidation contributes to IL-1β secretion in M2 macrophages and promotes macrophage-mediated tumor cell migration
- (2018) Qi Zhang et al. MOLECULAR IMMUNOLOGY
- Mechanisms of NAFLD development and therapeutic strategies
- (2018) Scott L. Friedman et al. NATURE MEDICINE
- Fatty acid metabolism complements glycolysis in the selective regulatory T cell expansion during tumor growth
- (2018) Ilenia Pacella et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lipid Droplets as Immune Modulators in Myeloid Cells
- (2018) Martijn H. den Brok et al. TRENDS IN IMMUNOLOGY
- Regulatory T Cell Metabolism in the Hepatic Microenvironment
- (2018) Rebecca Ellen Wawman et al. Frontiers in Immunology
- Lipid profiling of pre-treatment plasma reveals biomarker candidates associated with response rates and hand–foot skin reactions in sorafenib-treated patients
- (2018) Kosuke Saito et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Development of an in vitro model to study hepatitis C virus effects on hepatocellular lipotoxicity and lipid metabolism
- (2018) Leandra Koletzko et al. PATHOLOGY RESEARCH AND PRACTICE
- Immunometabolism: A novel perspective of liver cancer microenvironment and its influence on tumor progression
- (2018) Qi Zhang et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Integrative genomic analysis of mouse and human hepatocellular carcinoma
- (2018) Michelle Dow et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metabolic network-based stratification of hepatocellular carcinoma reveals three distinct tumor subtypes
- (2018) Gholamreza Bidkhori et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nonalcoholic Fatty Liver Disease
- (2018) Irene Pierantonelli et al. TRANSPLANTATION
- Lipid Metabolic Reprogramming in Hepatocellular Carcinoma
- (2018) Hayato Nakagawa et al. Cancers
- Fatty acid synthase (FASN) as a therapeutic target in breast cancer
- (2017) Javier A. Menendez et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Pleiotrophin, a target of miR-384, promotes proliferation, metastasis and lipogenesis in HBV-related hepatocellular carcinoma
- (2017) Pei-song Bai et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Stearoyl-CoA desaturase regulates sorafenib resistance via modulation of ER stress-induced differentiation
- (2017) Mark Kin Fai Ma et al. JOURNAL OF HEPATOLOGY
- Toxic effects of phytol and retinol on human glioblastoma cells are associated with modulation of cholesterol and fatty acid biosynthetic pathways
- (2017) Gustavo Facchini et al. JOURNAL OF NEURO-ONCOLOGY
- Exogenous lipid uptake induces metabolic and functional reprogramming of tumor-associated myeloid-derived suppressor cells
- (2017) Amir A. Al-Khami et al. OncoImmunology
- Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated Lipogenesis
- (2016) F. Geng et al. CLINICAL CANCER RESEARCH
- Acetyl-coenzyme A carboxylase alpha promotion of glucose-mediated fatty acid synthesis enhances survival of hepatocellular carcinoma in mice and patients
- (2016) Ming-Da Wang et al. HEPATOLOGY
- The Proteomic Landscape of Human Ex Vivo Regulatory and Conventional T Cells Reveals Specific Metabolic Requirements
- (2016) Claudio Procaccini et al. IMMUNITY
- Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation
- (2016) Stanley Ching-Cheng Huang et al. IMMUNITY
- Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice and humans
- (2016) Lei Li et al. JOURNAL OF HEPATOLOGY
- Oral intake of 7-dehydrocholesterol increases vitamin D 3 concentrations in the liver and kidney
- (2016) Julia Kühn et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- NAFLD causes selective CD4+ T lymphocyte loss and promotes hepatocarcinogenesis
- (2016) Chi Ma et al. NATURE
- MicroRNA-1207-5p inhibits hepatocellular carcinoma cell growth and invasion through the fatty acid synthase-mediated Akt/mTOR signalling pathway
- (2016) Gang Zhao et al. ONCOLOGY REPORTS
- PPARs and Mitochondrial Metabolism: From NAFLD to HCC
- (2016) Tommaso Mello et al. PPAR Research
- Saponin-based adjuvants induce cross-presentation in dendritic cells by intracellular lipid body formation
- (2016) Martijn H. den Brok et al. Nature Communications
- HBx regulates fatty acid oxidation to promote hepatocellular carcinoma survival during metabolic stress
- (2016) Ming-Da Wang et al. Oncotarget
- Hepatitis B virus X induces inflammation and cancer in mice liver through dysregulation of cytoskeletal remodeling and lipid metabolism
- (2016) Zhongwei Xu et al. Oncotarget
- Longitudinal metabolic imaging of hepatocellular carcinoma in transgenic mouse models identifies acylcarnitine as a potential biomarker for early detection
- (2016) Jadegoud Yaligar et al. Scientific Reports
- Cholesterol-Independent SREBP-1 Maturation Is Linked to ARF1 Inactivation
- (2016) Lorissa J. Smulan et al. Cell Reports
- Lipid metabolic reprogramming in cancer cells
- (2016) S Beloribi-Djefaflia et al. Oncogenesis
- Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation
- (2015) Maria Ida Malandrino et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity
- (2015) Chao Wang et al. CELL
- ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis
- (2015) Juan R. Cubillos-Ruiz et al. CELL
- Peroxisomal Lipid Synthesis Regulates Inflammation by Sustaining Neutrophil Membrane Phospholipid Composition and Viability
- (2015) Irfan J. Lodhi et al. Cell Metabolism
- MicroRNAs and Noncoding RNAs in Hepatic Lipid and Lipoprotein Metabolism: Potential Therapeutic Targets of Metabolic Disorders
- (2015) Neetu Sud et al. DRUG DEVELOPMENT RESEARCH
- MicroRNA-21 is a potential link between non-alcoholic fatty liver disease and hepatocellular carcinoma via modulation of the HBP1-p53-Srebp1c pathway
- (2015) Heng Wu et al. GUT
- Characterization of hepatocellular carcinoma (HCC) in non-alcoholic fatty liver disease (NAFLD) patients without cirrhosis
- (2015) Bashar Mohamad et al. Hepatology International
- Metabolic Reprogramming of Immune Cells in Cancer Progression
- (2015) Subhra K. Biswas IMMUNITY
- T cell metabolism drives immunity
- (2015) Michael D. Buck et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Alternatively activated (M2) macrophages promote tumour growth and invasiveness in hepatocellular carcinoma
- (2015) Oscar W.H. Yeung et al. JOURNAL OF HEPATOLOGY
- Deletion of 5-Lipoxygenase in the Tumor Microenvironment Promotes Lung Cancer Progression and Metastasis through Regulating T Cell Recruitment
- (2015) Joanna M. Poczobutt et al. JOURNAL OF IMMUNOLOGY
- Tumor-Infiltrating Dendritic Cells in Cancer Pathogenesis
- (2015) Jo Marie Tran Janco et al. JOURNAL OF IMMUNOLOGY
- A biphasic response pattern of lipid metabolomics in the stage progression of hepatitis B virus X tumorigenesis
- (2015) Chiao-Fang Teng et al. MOLECULAR CARCINOGENESIS
- Metabolic control of regulatory T cell development and function
- (2015) Hu Zeng et al. TRENDS IN IMMUNOLOGY
- Overexpression of microRNA-30a-5p inhibits liver cancer cell proliferation and induces apoptosis by targeting MTDH/PTEN/AKT pathway
- (2015) Wen-fang Li et al. TUMOR BIOLOGY
- β-catenin alteration is rare in hepatocellular carcinoma with steatohepatitic features: immunohistochemical and mutational study
- (2015) Sumiyo Ando et al. VIRCHOWS ARCHIV
- PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation
- (2015) Nikolaos Patsoukis et al. Nature Communications
- M-CSF from Cancer Cells Induces Fatty Acid Synthase and PPARβ/δ Activation in Tumor Myeloid Cells, Leading to Tumor Progression
- (2015) Jonghanne Park et al. Cell Reports
- Obesity Drives Th17 Cell Differentiation by Inducing the Lipid Metabolic Kinase, ACC1
- (2015) Yusuke Endo et al. Cell Reports
- Inhibition of fatty acid oxidation modulates immunosuppressive functions of myeloid-derived suppressor cells and enhances cancer therapies
- (2015) Amir A Al-Khami et al. Journal for ImmunoTherapy of Cancer
- Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma
- (2015) Aritro Nath et al. Scientific Reports
- miR-613 regulates cholesterol efflux by targeting LXRα and ABCA1 in PPARγ activated THP-1 macrophages
- (2014) Ranzun Zhao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Involvement of cholesterol in hepatitis B virus X protein-induced abnormal lipid metabolism of hepatoma cells via up-regulating miR-205-targeted ACSL4
- (2014) Ming Cui et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- MiR-205 modulates abnormal lipid metabolism of hepatoma cells via targeting acyl-CoA synthetase long-chain family member 1 (ACSL1) mRNA
- (2014) Ming Cui et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Fatty Acid-Binding Protein E-FABP Restricts Tumor Growth by Promoting IFN- Responses in Tumor-Associated Macrophages
- (2014) Y. Zhang et al. CANCER RESEARCH
- LXR-dependent and -independent effects of oxysterols on immunity and tumor growth
- (2014) Catia Traversari et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- PD-1 regulates extrathymic regulatory T-cell differentiation
- (2014) Xiufen Chen et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Fatty acids increase hepatitis B virus X protein stabilization and HBx-induced inflammatory gene expression
- (2014) Hyun Kook Cho et al. FEBS Journal
- Evaluation of cytotoxic effects of 7-dehydrocholesterol on melanoma cells
- (2014) Monica Gelzo et al. FREE RADICAL BIOLOGY AND MEDICINE
- Inhibition of microRNA-24 expression in liver prevents hepatic lipid accumulation and hyperlipidemia
- (2014) Raymond Ng et al. HEPATOLOGY
- Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012
- (2014) Jacques Ferlay et al. INTERNATIONAL JOURNAL OF CANCER
- Prognostic impact of programmed cell death 1 ligand 1 expression in human leukocyte antigen class I-positive hepatocellular carcinoma after curative hepatectomy
- (2014) Yuichiroh Umemoto et al. JOURNAL OF GASTROENTEROLOGY
- Oxidized Lipids Block Antigen Cross-Presentation by Dendritic Cells in Cancer
- (2014) W. Cao et al. JOURNAL OF IMMUNOLOGY
- Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages
- (2014) Stanley Ching-Cheng Huang et al. NATURE IMMUNOLOGY
- TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation
- (2014) Bart Everts et al. NATURE IMMUNOLOGY
- Higher Frequencies of GARP+CTLA-4+Foxp3+ T Regulatory Cells and Myeloid-Derived Suppressor Cells in Hepatocellular Carcinoma Patients Are Associated with Impaired T-Cell Functionality
- (2013) S. Kalathil et al. CANCER RESEARCH
- An SREBP-Responsive microRNA Operon Contributes to a Regulatory Loop for Intracellular Lipid Homeostasis
- (2013) Tae-Il Jeon et al. Cell Metabolism
- Integrated Metabolite and Gene Expression Profiles Identify Lipid Biomarkers Associated With Progression of Hepatocellular Carcinoma and Patient Outcomes
- (2013) Anuradha Budhu et al. GASTROENTEROLOGY
- mTORC1 couples immune signals and metabolic programming to establish Treg-cell function
- (2013) Hu Zeng et al. NATURE
- Sterol regulatory element–binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity
- (2013) Yoko Kidani et al. NATURE IMMUNOLOGY
- Genetic Analyses Reveal a Role for Vitamin D Insufficiency in HCV-Associated Hepatocellular Carcinoma Development
- (2013) Christian M. Lange et al. PLoS One
- MiR-155 Has a Protective Role in the Development of Non-Alcoholic Hepatosteatosis in Mice
- (2013) Ashley M. Miller et al. PLoS One
- Pro-Inflammatory Activated Kupffer Cells by Lipids Induce Hepatic NKT Cells Deficiency through Activation-Induced Cell Death
- (2013) Tongfang Tang et al. PLoS One
- Macrophage-Induced Tumor Angiogenesis Is Regulated by the TSC2-mTOR Pathway
- (2012) W. Chen et al. CANCER RESEARCH
- Activated tumor-infiltrating CD4+ regulatory T cells restrain antitumor immunity in patients with primary or metastatic liver cancer
- (2012) Alexander Pedroza-Gonzalez et al. HEPATOLOGY
- Monocyte/macrophage-elicited natural killer cell dysfunction in hepatocellular carcinoma is mediated by CD48/2B4 interactions
- (2012) Yan Wu et al. HEPATOLOGY
- Distinct metabolic programs in activated T cells: opportunities for selective immunomodulation
- (2012) Daniel R. Wahl et al. IMMUNOLOGICAL REVIEWS
- Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice
- (2012) L. Wu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hepatocellular carcinoma and macrophage interaction induced tumor immunosuppressionviaTreg requires TLR4 signaling
- (2012) Jing Yang WORLD JOURNAL OF GASTROENTEROLOGY
- AKT (v-akt murine thymoma viral oncogene homolog 1) and N-Ras (neuroblastoma ras viral oncogene homolog) coactivation in the mouse liver promotes rapid carcinogenesis by way of mTOR (mammalian target of rapamycin complex 1), FOXM1 (forkhead box M1)/SKP2,
- (2011) Coral Ho et al. HEPATOLOGY
- Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis
- (2011) Katey J. Rayner et al. JOURNAL OF CLINICAL INVESTIGATION
- Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
- (2011) R. D. Michalek et al. JOURNAL OF IMMUNOLOGY
- Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides
- (2011) Katey J. Rayner et al. NATURE
- Rab18 Dynamics in Adipocytes in Relation to Lipogenesis, Lipolysis and Obesity
- (2011) Marina R. Pulido et al. PLoS One
- FATP2 is a hepatic fatty acid transporter and peroxisomal very long-chain acyl-CoA synthetase
- (2010) Alaric Falcon et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Immunity, Inflammation, and Cancer
- (2010) Sergei I. Grivennikov et al. CELL
- Fatty acid synthase as a potential therapeutic target in cancer
- (2010) Richard Flavin et al. Future Oncology
- Lipid accumulation and dendritic cell dysfunction in cancer
- (2010) Donna L Herber et al. NATURE MEDICINE
- miR-33 links SREBP-2 induction to repression of sterol transporters
- (2010) T. J. Marquart et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evidence of aberrant lipid metabolism in hepatitis C and hepatocellular carcinoma
- (2010) Jian-Min Wu et al. HPB
- Temporal Proteome and Lipidome Profiles Reveal Hepatitis C Virus-Associated Reprogramming of Hepatocellular Metabolism and Bioenergetics
- (2010) Deborah L. Diamond et al. PLoS Pathogens
- Kupffer Cell Suppression of CD8+ T Cells in Human Hepatocellular Carcinoma Is Mediated by B7-H1/Programmed Death-1 Interactions
- (2009) K. Wu et al. CANCER RESEARCH
- High tumor-infiltrating macrophage density predicts poor prognosis in patients with primary hepatocellular carcinoma after resection
- (2008) Tong Ding et al. HUMAN PATHOLOGY
- Activation of lipogenic pathway correlates with cell proliferation and poor prognosis in hepatocellular carcinoma
- (2008) Taro Yamashita et al. JOURNAL OF HEPATOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now