Notch receptor expression in Trypanosoma cruzi ‐infected human umbilical vein endothelial cells treated with benznidazole or simvastatin revealed by microarray analysis

Overexpression of Trypanosoma cruzi High Mobility Group B protein (TcHMGB) alters the nuclear structure, impairs cytokinesis and reduces the parasite infectivity

(2019) Luis Emilio Tavernelli et al.   Scientific Reports

American Trypanosomiasis (Chagas Disease)

(2019) Luis E. Echeverria et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Notch signaling promotes angiogenesis and improves cardiac function after myocardial infarction

(2018) Xue-liang Zhou et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Chagas disease

(2018) José A Pérez-Molina et al.   LANCET

High-mobility group box 1 protein (HMGB1) operates as an alarmin outside as well as inside cells

(2018) Ulf Andersson et al.   SEMINARS IN IMMUNOLOGY

Host-parasite interaction: changes in human placental gene expression induced by Trypanosoma cruzi

(2018) Christian Castillo et al.   Parasites & Vectors

The β-blocker carvedilol and the benznidazole modulate the cardiac immune response in the acute infection induced by Colombian strain of the Trypanosoma cruzi

(2018) Aline Luciano Horta et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Elevated IL-17 levels and echocardiographic signs of preserved myocardial function in benznidazole-treated individuals with chronic Chagas’ disease

(2018) Edmundo J.N. Camara et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Pathology and Pathogenesis of Chagas Heart Disease

(2018) Kevin M. Bonney et al.   Annual Review of Pathology-Mechanisms of Disease

Chronic Chagas cardiomyopathy: a review of the main pathogenic mechanisms and the efficacy of aetiological treatment following the BENznidazole Evaluation for Interrupting Trypanosomiasis (BENEFIT) trial

(2017) Anis Rassi Jr et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Benznidazole, the trypanocidal drug used for Chagas disease, induces hepatic NRF2 activation and attenuates the inflammatory response in a murine model of sepsis

(2017) Flavia Lambertucci et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Notch Signaling in Ischemic Damage and Fibrosis: Evidence and Clues from the Heart

(2017) Silvia Nistri et al.   Frontiers in Pharmacology

Chagas cardiomyopathy: The potential effect of benznidazole treatment on diastolic dysfunction and cardiac damage in dogs chronically infected with Trypanosoma cruzi

(2016) Fabiane M. Santos et al.   ACTA TROPICA

Immune responses against protozoan parasites: a focus on the emerging role of Nod-like receptors

(2016) Prajwal Gurung et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Notch1 is associated with the differentiation of human bone marrow-derived mesenchymal stem cells to cardiomyocytes

(2016) Zipu Yu et al.   Molecular Medicine Reports

Transcriptome Remodeling in Trypanosoma cruzi and Human Cells during Intracellular Infection

(2016) Yuan Li et al.   PLoS Pathogens

Endocardial Notch Signaling in Cardiac Development and Disease

(2015) Guillermo Luxán et al.   CIRCULATION RESEARCH

Randomized Trial of Benznidazole for Chronic Chagas’ Cardiomyopathy

(2015) Carlos A. Morillo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chagas’ Disease

(2015) Caryn Bern   NEW ENGLAND JOURNAL OF MEDICINE

Intramyocardial Delivery ofNotchLigand-Containing Hydrogels Improves Cardiac Function and Angiogenesis Following Infarction

(2015) Archana V. Boopathy et al.   TISSUE ENGINEERING PART A

Simvastatin and Benznidazole-Mediated Prevention of Trypanosoma cruzi-Induced Endothelial Activation: Role of 15-epi-lipoxin A4 in the Action of Simvastatin

(2015) Carolina Campos-Estrada et al.   PLoS Neglected Tropical Diseases

Fold change rank ordering statistics: a new method for detecting differentially expressed genes

(2014) Doulaye Dembélé et al.   BMC BIOINFORMATICS

The Notch pathway: a novel target for myocardial remodelling therapy?

(2014) R. Ferrari et al.   EUROPEAN HEART JOURNAL

Innate and Adaptive Inflammation as a Therapeutic Target in Vascular Disease

(2014) Dimitris Tousoulis et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Randomized Trial of Posaconazole and Benznidazole for Chronic Chagas' Disease

(2014) Israel Molina et al.   NEW ENGLAND JOURNAL OF MEDICINE

Fetal–maternal communication: the role of Notch signalling in embryo implantation

(2014) Carly Cuman et al.   REPRODUCTION

EarlyTrypanosoma cruziInfection Reprograms Human Epithelial Cells

(2014) María Laura Chiribao et al.   Biomed Research International

Benznidazole prevents endothelial damage in an experimental model of Chagas disease

(2013) Alfredo Molina-Berríos et al.   ACTA TROPICA

Towards a Paradigm Shift in the Treatment of Chronic Chagas Disease

(2013) R. Viotti et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Impact of Notch Signaling on Inflammatory Responses in Cardiovascular Disorders

(2013) Thibaut Quillard et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Protection of vascular endothelium by aspirin in a murine model of chronic Chagas’ disease

(2013) Alfredo Molina-Berríos et al.   PARASITOLOGY RESEARCH

Cardiomyopathy prognosis after benznidazole treatment in chronic canine Chagas' disease

(2012) F. M. Santos et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Notch Signaling as an Important Mediator of Cardiac Repair and Regeneration After Myocardial Infarction

(2012) Yuxin Li et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Trypanosoma cruzi Infection Induces a Global Host Cell Response in Cardiomyocytes

(2011) Patricio A. Manque et al.   INFECTION AND IMMUNITY

Benznidazole treatment attenuates liver NF-κB activity and MAPK in a cecal ligation and puncture model of sepsis

(2011) María Teresa Ronco et al.   MOLECULAR IMMUNOLOGY

A Dynamic Notch Injury Response Activates Epicardium and Contributes to Fibrosis Repair

(2010) Jamie L. Russell et al.   CIRCULATION RESEARCH

Chagas disease, adipose tissue and the metabolic syndrome

(2009) Fnu Nagajyothi et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ