Simvastatin and Benznidazole-Mediated Prevention of Trypanosoma cruzi-Induced Endothelial Activation: Role of 15-epi-lipoxin A4 in the Action of Simvastatin

Proresolving Lipid Mediators and Mechanisms in the Resolution of Acute Inflammation

(2014) Christopher D. Buckley et al.   IMMUNITY

Chagas disease: control, elimination and eradication. Is it possible?

(2014) Jose Rodrigues Coura   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Elevated Levels of Plasma TNF-α Are Associated With Microvascular Endothelial Dysfunction in Patients With Sepsis Through Activating the NF-κB and p38 Mitogen-Activated Protein Kinase in Endothelial Cells

(2014) Yingjian Liang et al.   SHOCK

Benznidazole prevents endothelial damage in an experimental model of Chagas disease

(2013) Alfredo Molina-Berríos et al.   ACTA TROPICA

Mepivacaine-induced contraction involves phosphorylation of extracellular signal-regulated kinase through activation of the lipoxygenase pathway in isolated rat aortic smooth muscle

(2013) Hyo Min Lee et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Protective Role of Acetylsalicylic Acid in Experimental Trypanosoma cruzi Infection: Evidence of a 15-epi-Lipoxin A4-Mediated Effect

(2013) Alfredo Molina-Berríos et al.   PLoS Neglected Tropical Diseases

The role of transient receptor potential channel blockers in human gastric cancer cell viability

(2012) Byung Joo Kim et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Simvastatin and atorvastatin attenuate VCAM-1 and uPAR expression on human endothelial cells and platelet surface expression of CD40 ligand

(2012) Ksenija Stach et al.   Cardiology Journal

Pleiotropic Effects of Statins: The Role of Eicosanoid Production

(2012) Yochai Birnbaum et al.   Current Atherosclerosis Reports

American Trypanosomiasis (Chagas Disease)

(2012) Anis Rassi et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Simvastatin reduces VCAM-1 expression in human umbilical vein endothelial cells exposed to lipopolysaccharide

(2012) Johnson Chia-Shen Yang et al.   INFLAMMATION RESEARCH

Short-term therapy with simvastatin reduces inflammatory mediators and heart inflammation during the acute phase of experimental Chagas disease

(2012) Rafael Rodrigues Silva et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Diagnosis and management of Chagas disease and cardiomyopathy

(2012) Antonio L. Ribeiro et al.   Nature Reviews Cardiology

Current understanding of immunity to Trypanosoma cruzi infection and pathogenesis of Chagas disease

(2012) Fabiana S. Machado et al.   Seminars in Immunopathology

Simvastatin disrupts cytoskeleton and decreases cardiac fibroblast adhesion, migration and viability

(2012) Miguel Copaja et al.   TOXICOLOGY

Lipoxin A4 inhibits immune cell binding to salivary epithelium and vascular endothelium

(2011) Sreedevi Chinthamani et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Low Doses of Simvastatin Therapy Ameliorate Cardiac Inflammatory Remodeling in Trypanosoma cruzi-Infected Dogs

(2011) Lilian Melo et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Trypanosoma cruzi invades host cells through the activation of endothelin and bradykinin receptors: a converging pathway leading to chagasic vasculopathy

(2011) Daniele Andrade et al.   BRITISH JOURNAL OF PHARMACOLOGY

Constitutive Expression and Enzymatic Cleavage of ICAM-1 in the Spontaneously Hypertensive Rat

(2011) Sheng Tong et al.   JOURNAL OF VASCULAR RESEARCH

Benznidazole treatment attenuates liver NF-κB activity and MAPK in a cecal ligation and puncture model of sepsis

(2011) María Teresa Ronco et al.   MOLECULAR IMMUNOLOGY

Benznidazole Therapy Modulates Interferon-γ and M2 Muscarinic Receptor Autoantibody Responses in Trypanosoma cruzi-Infected Children

(2011) Romina A. Cutrullis et al.   PLoS One

The Direct Effect of Levobupivacaine in Isolated Rat Aorta Involves Lipoxygenase Pathway Activation and Endothelial Nitric Oxide Release

(2010) Yun Suk Choi et al.   ANESTHESIA AND ANALGESIA

5-Lipoxygenase is a key determinant of acute myocardial inflammation and mortality during Trypanosoma cruzi infection

(2010) Wander R. Pavanelli et al.   MICROBES AND INFECTION

Benznidazole blocks NF-κB activation but not AP-1 through inhibition of IKK

(2010) Romina Manarin et al.   MOLECULAR IMMUNOLOGY

Coronary Microvascular Disease in Chronic Chagas Cardiomyopathy Including an Overview on History, Pathology, and Other Proposed Pathogenic Mechanisms

(2010) Marcos A. Rossi et al.   PLoS Neglected Tropical Diseases

A semi-quantitative assay to screen for angiogenic compounds and compounds with angiogenic potential using the EA.hy926 endothelial cell line

(2009) EVELYN ARANDA et al.   BIOLOGICAL RESEARCH

Trypanosoma cruzi: In vitro effect of aspirin with nifurtimox and benznidazole

(2009) Rodrigo López-Muñoz et al.   EXPERIMENTAL PARASITOLOGY