Kinetics of cytokine receptor trafficking determine signaling and functional selectivity
出版年份 2019 全文链接
标题
Kinetics of cytokine receptor trafficking determine signaling and functional selectivity
作者
关键词
-
出版物
eLife
Volume 8, Issue -, Pages -
出版商
eLife Sciences Publications, Ltd
发表日期
2019-11-27
DOI
10.7554/elife.49314
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- A molecular assembly phase transition and kinetic proofreading modulate Ras activation by SOS
- (2019) William Y. C. Huang et al. SCIENCE
- Structure and dynamics of GPCR signaling complexes
- (2018) Daniel Hilger et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structure and dynamics of GPCR signaling complexes
- (2018) Daniel Hilger et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mechanisms of signalling and biased agonism in G protein-coupled receptors
- (2018) Denise Wootten et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mapping Determinants of Cytokine Signaling via Protein Engineering
- (2018) Claire Gorby et al. Frontiers in Immunology
- The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity
- (2017) Juan L. Mendoza et al. IMMUNITY
- Signal processing by the endosomal system
- (2016) Roberto Villaseñor et al. CURRENT OPINION IN CELL BIOLOGY
- Endocytic regulation of cytokine receptor signaling
- (2016) Jaroslaw Cendrowski et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells
- (2016) Sylvia Heink et al. NATURE IMMUNOLOGY
- Phosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in recruitment dynamics of the Ras activator SOS
- (2016) William Y. C. Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Receptor dimer stabilization by hierarchical plasma membrane microcompartments regulates cytokine signaling
- (2016) C. You et al. Science Advances
- Insights into Cytokine–Receptor Interactions from Cytokine Engineering
- (2015) Jamie B. Spangler et al. Annual Review of Immunology
- Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands
- (2015) Ignacio Moraga et al. CELL
- Interleukin-2 Activity Can Be Fine Tuned with Engineered Receptor Signaling Clamps
- (2015) Suman Mitra et al. IMMUNITY
- Type I Interferon Signaling Is Decoupled from Specific Receptor Orientation through Lenient Requirements of the Transmembrane Domain
- (2015) Nanaocha Sharma et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Receptor dimerization dynamics as a regulatory valve for plasticity of type I interferon signaling
- (2015) Stephan Wilmes et al. JOURNAL OF CELL BIOLOGY
- IL-6 as a keystone cytokine in health and disease
- (2015) Christopher A Hunter et al. NATURE IMMUNOLOGY
- Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency
- (2015) Ignacio Moraga et al. Science Signaling
- Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency
- (2015) Ignacio Moraga et al. Science Signaling
- Dynamics and Interaction of Interleukin-4 Receptor Subunits in Living Cells
- (2014) Hetvi Gandhi et al. BIOPHYSICAL JOURNAL
- A Conserved IFN- Receptor Tyrosine Motif Directs the Biological Response to Type I IFNs
- (2014) W. Zhao et al. JOURNAL OF IMMUNOLOGY
- Noise estimation for off-axis electron holography
- (2014) Falk Röder et al. ULTRAMICROSCOPY
- Structural and dynamic determinants of type I interferon receptor assembly and their functional interpretation
- (2012) Jacob Piehler et al. IMMUNOLOGICAL REVIEWS
- Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15
- (2012) Aaron M Ring et al. NATURE IMMUNOLOGY
- STAT1:DNA sequence-dependent binding modulation by phosphorylation, protein:protein interactions and small-molecule inhibition
- (2012) Andrew J. Bonham et al. NUCLEIC ACIDS RESEARCH
- The STAT3 beacon: IL-6 recurrently activates STAT 3 from endosomal structures
- (2011) Christopher L. German et al. EXPERIMENTAL CELL RESEARCH
- T-cell tolerance and the multi-functional role of IL-2R signaling in T-regulatory cells
- (2011) Guoyan Cheng et al. IMMUNOLOGICAL REVIEWS
- Inhibition of Classic Signaling Is a Novel Function of Soluble Glycoprotein 130 (sgp130), Which Is Controlled by the Ratio of Interleukin 6 and Soluble Interleukin 6 Receptor
- (2011) Christoph Garbers et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Membrane trafficking and signaling: Two sides of the same coin
- (2011) Pauline Gonnord et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Functional Immobilization and Patterning of Proteins by an Enzymatic Transfer Reaction
- (2010) Sharon Waichman et al. ANALYTICAL CHEMISTRY
- Cell Signaling by Receptor Tyrosine Kinases
- (2010) Mark A. Lemmon et al. CELL
- IL-6: Regulator of Treg/Th17 balance
- (2010) Akihiro Kimura et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Ubiquitination Regulates the Internalization, Endolysosomal Sorting, and Signaling of the Erythropoietin Receptor
- (2010) Gamze Betul Bulut et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Loss of CD4 + T Cell IL-6R Expression during Inflammation Underlines a Role for IL-6 Trans Signaling in the Local Maintenance of Th17 Cells
- (2010) Gareth W. Jones et al. JOURNAL OF IMMUNOLOGY
- A role for IL-27p28 as an antagonist of gp130-mediated signaling
- (2010) Jason S Stumhofer et al. NATURE IMMUNOLOGY
- Covering a Broad Dynamic Range: Information Processing at the Erythropoietin Receptor
- (2010) V. Becker et al. SCIENCE
- Development and function of TH17 cells in health and disease
- (2009) Jennifer Louten et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Biochemical Monitoring of the Early Endocytic Traffic of the Type I Interferon Receptor
- (2009) Béatrice Payelle-Brogard et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Modulation of protein properties in living cells using nanobodies
- (2009) Axel Kirchhofer et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A Reducing and Oxidizing System Minimizes Photobleaching and Blinking of Fluorescent Dyes
- (2008) Jan Vogelsang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System
- (2008) Sherry L. LaPorte et al. CELL
- c-Cbl-Dependent Monoubiquitination and Lysosomal Degradation of gp130
- (2008) Y. Tanaka et al. MOLECULAR AND CELLULAR BIOLOGY
- Priming for T helper type 2 differentiation by interleukin 2–mediated induction of interleukin 4 receptor α-chain expression
- (2008) Wei Liao et al. NATURE IMMUNOLOGY
- Dynamic multiple-target tracing to probe spatiotemporal cartography of cell membranes
- (2008) Arnauld Sergé et al. NATURE METHODS
- IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells
- (2008) T. Korn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Type I IL-4Rs Selectively Activate IRS-2 to Induce Target Gene Expression in Macrophages
- (2008) N. M. Heller et al. Science Signaling
- Structural Biology of Shared Cytokine Receptors
- (2007) Xinquan Wang et al. Annual Review of Immunology
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