标题
Genetic determinants of cellular addiction to DNA polymerase theta
作者
关键词
-
出版物
Nature Communications
Volume 10, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-09-19
DOI
10.1038/s41467-019-12234-1
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- 53BP1 nuclear bodies enforce replication timing at under-replicated DNA to limit heritable DNA damage
- (2019) Julian Spies et al. NATURE CELL BIOLOGY
- Repair of DNA double-strand breaks by mammalian alternative end-joining pathways
- (2018) Annahita Sallmyr et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Carboplatin in BRCA1/2-mutated and triple-negative breast cancer BRCAness subgroups: the TNT Trial
- (2018) Andrew Tutt et al. NATURE MEDICINE
- Beyond PARP—POLθ as an anticancer target
- (2018) Geoff S. Higgins et al. SCIENCE
- Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas
- (2018) Theo A. Knijnenburg et al. Cell Reports
- A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer
- (2017) Paz Polak et al. NATURE GENETICS
- HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures
- (2017) Helen Davies et al. NATURE MEDICINE
- Salmon provides fast and bias-aware quantification of transcript expression
- (2017) Rob Patro et al. NATURE METHODS
- Non-homologous DNA end joining and alternative pathways to double-strand break repair
- (2017) Howard H. Y. Chang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization
- (2017) Serif Senturk et al. Nature Communications
- Dual loss of human POLQ and LIG4 abolishes random integration
- (2017) Shinta Saito et al. Nature Communications
- Inactivation of Pol θ and C-NHEJ eliminates off-target integration of exogenous DNA
- (2017) Alex N. Zelensky et al. Nature Communications
- BRCA2 suppresses replication stress-induced mitotic and G1 abnormalities through homologous recombination
- (2017) Weiran Feng et al. Nature Communications
- Pan-cancer analysis of bi-allelic alterations in homologous recombination DNA repair genes
- (2017) Nadeem Riaz et al. Nature Communications
- Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens
- (2017) David W. Morgens et al. Nature Communications
- Loss of NEIL3 DNA glycosylase markedly increases replication associated double strand breaks and enhances sensitivity to ATR inhibitor in glioblastoma cells
- (2017) Alex W. Klattenhoff et al. Oncotarget
- Drosophila DNA polymerase theta utilizes both helicase-like and polymerase domains during microhomology-mediated end joining and interstrand crosslink repair
- (2017) Kelly Beagan et al. PLoS Genetics
- A novel ultra high-throughput 16S rRNA gene amplicon sequencing library preparation method for the Illumina HiSeq platform
- (2017) Eric J. de Muinck et al. Microbiome
- Orchestration of DNA Damage Checkpoint Dynamics across the Human Cell Cycle
- (2017) Hui Xiao Chao et al. Cell Systems
- SeqPurge: highly-sensitive adapter trimming for paired-end NGS data
- (2016) Marc Sturm et al. BMC BIOINFORMATICS
- DNA polymerase θ (POLQ), double-strand break repair, and cancer
- (2016) Richard D. Wood et al. DNA REPAIR
- When Genome Maintenance Goes Badly Awry
- (2016) Elizabeth M. Kass et al. MOLECULAR CELL
- Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks
- (2016) David W. Wyatt et al. MOLECULAR CELL
- G-quadruplex recognition and remodeling by the FANCJ helicase
- (2016) Colin G. Wu et al. NUCLEIC ACIDS RESEARCH
- Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells
- (2016) Alberto Moreno et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair
- (2015) Raphael Ceccaldi et al. NATURE
- Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination
- (2015) Pedro A. Mateos-Gomez et al. NATURE
- Essential role for polymerase specialization in cellular nonhomologous end joining
- (2015) John M. Pryor et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?
- (2015) Agnel Sfeir et al. TRENDS IN BIOCHEMICAL SCIENCES
- Mutagenic consequences of a single G-quadruplex demonstrate mitotic inheritance of DNA replication fork barriers
- (2015) Bennie Lemmens et al. Nature Communications
- Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis
- (2015) Robin van Schendel et al. Nature Communications
- ABRA: improved coding indel detection via assembly-based realignment
- (2014) Lisle E. Mose et al. BIOINFORMATICS
- FANCJ promotes DNA synthesis through G-quadruplex structures
- (2014) P. Castillo Bosch et al. EMBO JOURNAL
- Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans
- (2014) S. F. Roerink et al. GENOME RESEARCH
- Improved vectors and genome-wide libraries for CRISPR screening
- (2014) Neville E Sanjana et al. NATURE METHODS
- Integrated RNA and DNA sequencing improves mutation detection in low purity tumors
- (2014) Matthew D. Wilkerson et al. NUCLEIC ACIDS RESEARCH
- Sources of DNA Double-Strand Breaks and Models of Recombinational DNA Repair
- (2014) A. Mehta et al. Cold Spring Harbor Perspectives in Biology
- A Polymerase Theta-dependent repair pathway suppresses extensive genomic instability at endogenous G4 DNA sites
- (2014) Wouter Koole et al. Nature Communications
- The fidelity of the ligation step determines how ends are resolved during nonhomologous end joining
- (2014) Crystal A. Waters et al. Nature Communications
- Mechanism of Suppression of Chromosomal Instability by DNA Polymerase POLQ
- (2014) Matthew J. Yousefzadeh et al. PLoS Genetics
- How unfinished business from S-phase affects mitosis and beyond
- (2013) Hocine W Mankouri et al. EMBO JOURNAL
- The Mre11 Complex Suppresses Oncogene-Driven Breast Tumorigenesis and Metastasis
- (2013) Gaorav P. Gupta et al. MOLECULAR CELL
- Signatures of mutational processes in human cancer
- (2013) Ludmil B. Alexandrov et al. NATURE
- Strelka: accurate somatic small-variant calling from sequenced tumor–normal sample pairs
- (2012) Christopher T. Saunders et al. BIOINFORMATICS
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Mutational Processes Molding the Genomes of 21 Breast Cancers
- (2012) Serena Nik-Zainal et al. CELL
- Playing the End Game: DNA Double-Strand Break Repair Pathway Choice
- (2012) J. Ross Chapman et al. MOLECULAR CELL
- Comprehensive molecular portraits of human breast tumours
- (2012) Daniel C. Koboldt et al. NATURE
- Small-molecule–induced DNA damage identifies alternative DNA structures in human genes
- (2012) Raphaël Rodriguez et al. Nature Chemical Biology
- 53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress
- (2011) Claudia Lukas et al. NATURE CELL BIOLOGY
- 53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks
- (2010) Samuel F. Bunting et al. CELL
- Dual Roles for DNA Polymerase Theta in Alternative End-Joining Repair of Double-Strand Breaks in Drosophila
- (2010) Sze Ham Chan et al. PLoS Genetics
- Enzymatic assembly of DNA molecules up to several hundred kilobases
- (2009) Daniel G Gibson et al. NATURE METHODS
- Caenorhabditis elegans POLQ-1 and HEL-308 function in two distinct DNA interstrand cross-link repair pathways
- (2008) Diego M. Muzzini et al. DNA REPAIR
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now