A general strategy for diversifying complex natural products to polycyclic scaffolds with medium-sized rings
出版年份 2019 全文链接
标题
A general strategy for diversifying complex natural products to polycyclic scaffolds with medium-sized rings
作者
关键词
-
出版物
Nature Communications
Volume 10, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-09-05
DOI
10.1038/s41467-019-11976-2
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The importance of synthetic chemistry in the pharmaceutical industry
- (2019) Kevin R. Campos et al. SCIENCE
- Transition-Metal-Catalyzed Selective Functionalization of C(sp3 )−H Bonds in Natural Products
- (2018) Rashad R. Karimov et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Electrifying Organic Synthesis
- (2018) Anton Wiebe et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Reagent-controlled regiodivergent ring expansions of steroids
- (2018) Manwika Charaschanya et al. Nature Communications
- Scalable, Electrochemical Oxidation of Unactivated C–H Bonds
- (2017) Yu Kawamata et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Synthetic nat- or ent-steroids in as few as five chemical steps from epichlorohydrin
- (2017) Wan Shin Kim et al. Nature Chemistry
- Site-selective oxidation, amination and epimerization reactions of complex polyols enabled by transfer hydrogenation
- (2017) Christopher K. Hill et al. Nature Chemistry
- Natural Products as Sources of New Drugs from 1981 to 2014
- (2016) David J. Newman et al. JOURNAL OF NATURAL PRODUCTS
- Nineteen-step total synthesis of (+)-phorbol
- (2016) Shuhei Kawamura et al. NATURE
- Scalable and sustainable electrochemical allylic C–H oxidation
- (2016) Evan J. Horn et al. NATURE
- Radical aryl migration enables diversity-oriented synthesis of structurally diverse medium/macro- or bridged-rings
- (2016) Lei Li et al. Nature Communications
- The Synthesis of Structurally Diverse Macrocycles By Successive Ring Expansion
- (2015) Christiana Kitsiou et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- CH Oxidation of Ingenanes Enables Potent and Selective Protein Kinase C Isoform Activation
- (2015) Yehua Jin et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Scalable C–H Oxidation with Copper: Synthesis of Polyoxypregnanes
- (2015) Yi Yang See et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Probing chemical space with alkaloid-inspired libraries
- (2014) Michael C. McLeod et al. Nature Chemistry
- Diversity-oriented synthesis as a tool for identifying new modulators of mitosis
- (2014) Brett M. Ibbeson et al. Nature Communications
- Importance and synthesis of benzannulated medium-sized and macrocyclic rings (BMRs)
- (2014) Altaf Hussain et al. RSC Advances
- Synthesis of Complex and Diverse Compounds through Ring Distortion of Abietic Acid
- (2013) Ryan J. Rafferty et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Natural products as starting points for the synthesis of complex and diverse compounds
- (2013) Karen C. Morrison et al. NATURAL PRODUCT REPORTS
- A ring-distortion strategy to construct stereochemically complex and structurally diverse compounds from natural products
- (2013) Robert W. Huigens III et al. Nature Chemistry
- A strategy for the diversity-oriented synthesis of macrocyclic scaffolds using multidimensional coupling
- (2013) Henning S. G. Beckmann et al. Nature Chemistry
- 14-Step Synthesis of (+)-Ingenol from (+)-3-Carene
- (2013) L. Jorgensen et al. SCIENCE
- Strategic Redox Relay Enables A Scalable Synthesis of Ouabagenin, A Bioactive Cardenolide
- (2013) H. Renata et al. SCIENCE
- Diversity-oriented synthesis: producing chemical tools for dissecting biology
- (2012) Cornelius J. O' Connor et al. CHEMICAL SOCIETY REVIEWS
- Macrocycles in new drug discovery
- (2012) Jamie Mallinson et al. Future Medicinal Chemistry
- Charting, Navigating, and Populating Natural Product Chemical Space for Drug Discovery
- (2012) Hugo Lachance et al. JOURNAL OF MEDICINAL CHEMISTRY
- Biomimetic diversity-oriented synthesis of benzannulated medium rings via ring expansion
- (2012) Renato A Bauer et al. Nature Chemical Biology
- A diversity-oriented synthesis approach to macrocycles via oxidative ring expansion
- (2012) Felix Kopp et al. Nature Chemical Biology
- Biology-Oriented Synthesis
- (2011) Stefan Wetzel et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Scalable enantioselective total synthesis of taxanes
- (2011) Abraham Mendoza et al. Nature Chemistry
- A Graphical Journey of Innovative Organic Architectures That Have Improved Our Lives
- (2010) Nicholas A. McGrath et al. JOURNAL OF CHEMICAL EDUCATION
- Novel Chemical Space Exploration via Natural Products
- (2009) Josefin Rosén et al. JOURNAL OF MEDICINAL CHEMISTRY
- Total synthesis of eudesmane terpenes by site-selective C–H oxidations
- (2009) Ke Chen et al. NATURE
- Quantifying biogenic bias in screening libraries
- (2009) Jérôme Hert et al. Nature Chemical Biology
- Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
- (2009) J. W.-H. Li et al. SCIENCE
- Natural products in drug discovery
- (2008) A HARVEY DRUG DISCOVERY TODAY
- Recent advances in azasteroids chemistry
- (2008) Malika Ibrahim-Ouali et al. STEROIDS
- Function-Oriented Synthesis, Step Economy, and Drug Design
- (2007) Paul A. Wender et al. ACCOUNTS OF CHEMICAL RESEARCH
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