A strategy for the diversity-oriented synthesis of macrocyclic scaffolds using multidimensional coupling
出版年份 2013 全文链接
标题
A strategy for the diversity-oriented synthesis of macrocyclic scaffolds using multidimensional coupling
作者
关键词
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出版物
Nature Chemistry
Volume 5, Issue 10, Pages 861-867
出版商
Springer Nature
发表日期
2013-08-23
DOI
10.1038/nchem.1729
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- A ring-distortion strategy to construct stereochemically complex and structurally diverse compounds from natural products
- (2013) Robert W. Huigens III et al. Nature Chemistry
- Structure-Based Macrocyclization Yields Hepatitis C Virus NS5B Inhibitors with Improved Binding Affinities and Pharmacokinetic Properties
- (2012) Maxwell D. Cummings et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Diversity-oriented synthesis: producing chemical tools for dissecting biology
- (2012) Cornelius J. O' Connor et al. CHEMICAL SOCIETY REVIEWS
- Biomimetic diversity-oriented synthesis of benzannulated medium rings via ring expansion
- (2012) Renato A Bauer et al. Nature Chemical Biology
- A diversity-oriented synthesis approach to macrocycles via oxidative ring expansion
- (2012) Felix Kopp et al. Nature Chemical Biology
- A two-directional strategy for the diversity-oriented synthesis of macrocyclic scaffolds
- (2012) Kieron M. G. O'Connell et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Biology-Oriented Synthesis
- (2011) Stefan Wetzel et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A design strategy for drug-like polyheterocycles with privileged substructures for discovery of specific small-molecule modulators
- (2011) Sangmi Oh et al. CHEMICAL COMMUNICATIONS
- Chemical genetics
- (2011) Cornelius J. O' Connor et al. CHEMICAL SOCIETY REVIEWS
- Biologically Active Macrocyclic Compounds - from Natural Products to Diversity-Oriented Synthesis
- (2011) Charlotte M. Madsen et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Macrocycles Are Great Cycles: Applications, Opportunities, and Challenges of Synthetic Macrocycles in Drug Discovery
- (2011) Eric Marsault et al. JOURNAL OF MEDICINAL CHEMISTRY
- Contemporary strategies for peptide macrocyclization
- (2011) Christopher J. White et al. Nature Chemistry
- Impact of high-throughput screening in biomedical research
- (2011) Ricardo Macarron et al. NATURE REVIEWS DRUG DISCOVERY
- Towards the systematic exploration of chemical space
- (2011) Mark Dow et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Discovery of new antimalarial chemotypes through chemical methodology and library development
- (2011) L. E. Brown et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fragment-based domain shuffling approach for the synthesis of pyran-based macrocycles
- (2011) E. Comer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Diversity-oriented synthesis of macrocyclic peptidomimetics
- (2011) A. Isidro-Llobet et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Peptoid Macrocycles: Making the Rounds with Peptidomimetic Oligomers
- (2010) Barney Yoo et al. CHEMISTRY-A EUROPEAN JOURNAL
- Expanding the range of ‘druggable’ targets with natural product-based libraries: an academic perspective
- (2010) Renato A Bauer et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- An Aldol-Based Build/Couple/Pair Strategy for the Synthesis of Medium- and Large-Sized Rings: Discovery of Macrocyclic Histone Deacetylase Inhibitors
- (2010) Lisa A. Marcaurelle et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Grand Challenge Commentary: Accessing new chemical space for 'undruggable' targets
- (2010) Sivaraman Dandapani et al. Nature Chemical Biology
- Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles
- (2010) P. A. Clemons et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Straightforward carbamoylation of nucleophilic compounds employing organic azides, phosphines, and aqueous trialkylammonium hydrogen carbonate
- (2010) Andrey Yagodkin et al. TETRAHEDRON
- Fluorous Linker-Facilitated Chemical Synthesis
- (2009) Wei Zhang CHEMICAL REVIEWS
- HTS and hit finding in academia – from chemical genomics to drug discovery
- (2009) Julie A. Frearson et al. DRUG DISCOVERY TODAY
- Synthesis of the First Calix[6]crypturea via a Versatile Tris-azide Precursor
- (2009) Mickaël Ménand et al. ORGANIC LETTERS
- Accessing Skeletal Diversity Using Catalyst Control: Formation ofnandn+ 1 Macrocyclic Triazole Rings
- (2009) Ann Rowley Kelly et al. ORGANIC LETTERS
- Synthesis of Natural-Product-Like Molecules with Over Eighty Distinct Scaffolds
- (2008) Daniel Morton et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Anti-MRSA Agent Discovery Using Diversity-Oriented Synthesis
- (2008) Gemma L. Thomas et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The exploration of macrocycles for drug discovery — an underexploited structural class
- (2008) Edward M. Driggers et al. NATURE REVIEWS DRUG DISCOVERY
- Towards the Optimal Screening Collection: A Synthesis Strategy
- (2007) Thomas E. Nielsen et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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