14-Step Synthesis of (+)-Ingenol from (+)-3-Carene

High-level semi-synthetic production of the potent antimalarial artemisinin

(2013) C. J. Paddon et al.   NATURE

Allylic Oxidations in Natural Product Synthesis

(2013) Masahisa Nakada et al.   SYNTHESIS-STUTTGART

Diterpenes from European Euphorbia Species Serving as Prototypes for Natural-Product-Based Drug Discovery

(2012) Andrea Vasas et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A Concise Synthesis of (+)-Artemisinin

(2012) Chunyin Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis: A constructive debate

(2012) Jay D. Keasling et al.   NATURE

Semisynthesis of Ingenol 3-Angelate (PEP005): Efficient Stereoconservative Angeloylation of Alcohols

(2012) Xifu Liang et al.   SYNLETT

PEP005 (ingenol mebutate) gel for the topical treatment of superficial basal cell carcinoma: Results of a randomized phase IIa trial

(2010) Greg Siller et al.   AUSTRALASIAN JOURNAL OF DERMATOLOGY

Cloning of casbene and neocembrene synthases from Euphorbiaceae plants and expression in Saccharomyces cerevisiae

(2010) James Kirby et al.   PHYTOCHEMISTRY

Manufacturing Molecules Through Metabolic Engineering

(2010) J. D. Keasling   SCIENCE

Redox Economy in Organic Synthesis

(2009) Noah Z. Burns et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total synthesis of eudesmane terpenes by site-selective C–H oxidations

(2009) Ke Chen et al.   NATURE

Function-Oriented Synthesis, Step Economy, and Drug Design

(2007) Paul A. Wender et al.   ACCOUNTS OF CHEMICAL RESEARCH