Structure of a P element transposase–DNA complex reveals unusual DNA structures and GTP-DNA contacts

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

DNA Repair in Drosophila : Mutagens, Models, and Missing Genes

(2017) Jeff Sekelsky   GENETICS

piRNA-mediated regulation of transposon alternative splicing in the soma and germ line

(2017) Felipe Karam Teixeira et al.   NATURE

RosettaES: a sampling strategy enabling automated interpretation of difficult cryo-EM maps

(2017) Brandon Frenz et al.   NATURE METHODS

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

Addressing preferred specimen orientation in single-particle cryo-EM through tilting

(2017) Yong Zi Tan et al.   NATURE METHODS

UCSF ChimeraX: Meeting modern challenges in visualization and analysis

(2017) Thomas D. Goddard et al.   PROTEIN SCIENCE

Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome

(2017) Dario Oliveira Passos et al.   SCIENCE

A supramolecular assembly mediates lentiviral DNA integration

(2017) Allison Ballandras-Colas et al.   SCIENCE

Structures of the CRISPR genome integration complex

(2017) Addison V. Wright et al.   SCIENCE

Riches in RAGs: Revealing the V(D)J Recombinase through High-Resolution Structures

(2017) Karla K. Rodgers   TRENDS IN BIOCHEMICAL SCIENCES

Target DNA bending by the Mu transpososome promotes careful transposition and prevents its reversal

(2017) James R Fuller et al.   eLife

DNA Repair in Drosophila : Mutagens, Models, and Missing Genes

(2017) Jeff Sekelsky   GENETICS

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Crystal structure of the Rous sarcoma virus intasome

(2016) Zhiqi Yin et al.   NATURE

Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function

(2016) Allison Ballandras-Colas et al.   NATURE

Regulatory activities of transposable elements: from conflicts to benefits

(2016) Edward B. Chuong et al.   NATURE REVIEWS GENETICS

A bend, flip and trap mechanism for transposon integration

(2016) Elizabeth R Morris et al.   eLife

Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures

(2015) Heng Ru et al.   CELL

Assembly Pathway and Characterization of the RAG1/2-DNA Paired and Signal-end Complexes

(2015) Mikalai Lapkouski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of the V(D)J recombinase RAG1–RAG2

(2015) Min-Sung Kim et al.   NATURE

Structural Basis of hAT Transposon End Recognition by Hermes, an Octameric DNA Transposase from Musca domestica

(2014) Alison B. Hickman et al.   CELL

The Human THAP9 Gene Encodes an Active P-Element DNA Transposase

(2013) S. Majumdar et al.   SCIENCE

The Mu transpososome structure sheds light on DDE recombinase evolution

(2012) Sherwin P. Montaño et al.   NATURE

Assembly of prototype foamy virus strand transfer complexes on product DNA bypassing catalysis of integration

(2012) Zhiqi Yin et al.   PROTEIN SCIENCE

Adaptation to P Element Transposon Invasion in Drosophila melanogaster

(2011) Jaspreet S. Khurana et al.   CELL

The Phenix software for automated determination of macromolecular structures

(2011) Paul D. Adams et al.   METHODS

The catalytic domain of all eukaryotic cut-and-paste transposase superfamilies

(2011) Y.-W. Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrating prokaryotes and eukaryotes: DNA transposases in light of structure

(2010) Alison Burgess Hickman et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

New baculovirus expression tools for recombinant protein complex production

(2010) Simon Trowitzsch et al.   JOURNAL OF STRUCTURAL BIOLOGY

The mechanism of retroviral integration from X-ray structures of its key intermediates

(2010) Goedele N. Maertens et al.   NATURE

THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves

(2009) Alex Sabogal et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Testing the palindromic target site model for DNA transposon insertion using the Drosophila melanogaster P-element

(2008) Raquel S. Linheiro et al.   NUCLEIC ACIDS RESEARCH