STAT3 controls osteoclast differentiation and bone homeostasis by regulating NFATc1 transcription

Interleukin-6 Interweaves the Bone Marrow Microenvironment, Bone Loss, and Multiple Myeloma

(2019) Danielle Harmer et al.   Frontiers in Endocrinology

Lkb1 deletion in periosteal mesenchymal progenitors induces osteogenic tumors through mTORC1 activation

(2019) Yujiao Han et al.   JOURNAL OF CLINICAL INVESTIGATION

Use of oral bisphosphonates and risk of hospital admission with osteonecrosis of the jaw: Large prospective cohort study in UK women

(2019) Clare J. Wotton et al.   BONE

The emerging role of Hippo signaling pathway in regulating osteoclast formation

(2018) Wanlei Yang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Discovery of a periosteal stem cell mediating intramembranous bone formation

(2018) Shawon Debnath et al.   NATURE

Force-induced increased osteogenesis enables accelerated orthodontic tooth movement in ovariectomized rats

(2017) Qinggang Dai et al.   Scientific Reports

Inactivation of Regulatory-associated Protein of mTOR (Raptor)/Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling in Osteoclasts Increases Bone Mass by Inhibiting Osteoclast Differentiation in Mice

(2016) Qinggang Dai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Postmenopausal Osteoporosis

(2016) Dennis M. Black et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mediator MED23 cooperates with RUNX2 to drive osteoblast differentiation and bone development

(2016) Zhen Liu et al.   Nature Communications

Methylsulfonylmethane Inhibits RANKL-Induced Osteoclastogenesis in BMMs by Suppressing NF-κB and STAT3 Activities

(2016) Youn Hee Joung et al.   PLoS One

Glycoprotein130 (Gp130)/interleukin-6 (IL-6) signalling in osteoclasts promotes bone formation in periosteal and trabecular bone

(2015) Rachelle W. Johnson et al.   BONE

The role of osteoclast differentiation and function in skeletal homeostasis

(2015) Kyoji Ikeda et al.   JOURNAL OF BIOCHEMISTRY

STAT3 selectively interacts with Smad3 to antagonize TGF-β

(2015) G Wang et al.   ONCOGENE

AG490 inhibits NFATc1 expression and STAT3 activation during RANKL induced osteoclastogenesis

(2013) Chang-hong Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2

(2013) Weiguo Zou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Osteoblast/osteocyte-specific inactivation of Stat3 decreases load-driven bone formation and accumulates reactive oxygen species

(2011) Hongkang Zhou et al.   BONE

IL-1  and TNF -initiated IL-6-STAT3 pathway is critical in mediating inflammatory cytokines and RANKL expression in inflammatory arthritis

(2011) T. Mori et al.   INTERNATIONAL IMMUNOLOGY

Transcriptional regulation of bone and joint remodeling by NFAT

(2009) Despina Sitara et al.   IMMUNOLOGICAL REVIEWS

PIAS3 negatively regulates RANKL-mediated osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblasts

(2008) T. Hikata et al.   BLOOD

NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism

(2008) Antonios O. Aliprantis et al.   JOURNAL OF CLINICAL INVESTIGATION