Xenobiotica-metabolizing enzymes in the lung of experimental animals, man and in human lung models
出版年份 2019 全文链接
标题
Xenobiotica-metabolizing enzymes in the lung of experimental animals, man and in human lung models
作者
关键词
-
出版物
ARCHIVES OF TOXICOLOGY
Volume 93, Issue 12, Pages 3419-3489
出版商
Springer Science and Business Media LLC
发表日期
2019-11-01
DOI
10.1007/s00204-019-02602-7
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Ontogeny and Biology of Human Small Airway Epithelial Club Cells
- (2018) Wu-Lin Zuo et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- A novel three-dimensional cell culture method enhances antiviral drug screening in primary human cells
- (2018) Robert Koban et al. ANTIVIRAL RESEARCH
- High-Fat Diets Alter the Modulatory Effects of Xenobiotics on Cytochrome P450 Activities
- (2018) Natalie C. Sadler et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Differential exposure and acute health impacts of inhaled solid-fuel emissions from rudimentary and advanced cookstoves in female CD-1 mice
- (2018) Eugene A. Gibbs-Flournoy et al. ENVIRONMENTAL RESEARCH
- Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: an exploratory analysis
- (2018) Kentaro Takahashi et al. EUROPEAN RESPIRATORY JOURNAL
- Hypermethylation of PGCP gene is associated with human bronchial epithelial cells immortalization
- (2018) Chen Gao et al. GENE
- Multifunctional Activity-Based Protein Profiling of the Developing Lung
- (2018) Ethan G. Stoddard et al. JOURNAL OF PROTEOME RESEARCH
- Inflammatory effects of acrolein, crotonaldehyde and hexanal vapors on human primary bronchial epithelial cells cultured at air-liquid interface
- (2018) Aishwarya M. Dwivedi et al. TOXICOLOGY IN VITRO
- Responsiveness assessment of a 3D tetra-culture alveolar model exposed to diesel exhaust particulate matter
- (2018) Ionel Fizeșan et al. TOXICOLOGY IN VITRO
- Organ-On-A-Chip Platforms: A Convergence of Advanced Materials, Cells, and Microscale Technologies
- (2018) Samad Ahadian et al. Advanced Healthcare Materials
- Tomorrow today: organ-on-a-chip advances towards clinically relevant pharmaceutical and medical in vitro models
- (2018) Mario Rothbauer et al. CURRENT OPINION IN BIOTECHNOLOGY
- Use of RNA-seq to determine variation in canine cytochrome P450 mRNA expression between blood, liver, lung, kidney and duodenum in healthy beagles
- (2017) M. Visser et al. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS
- A 3D Human Airway Model Enables Prediction of Respiratory Toxicity of Inhaled Drugs In Vitro
- (2017) Kinga Balogh Sivars et al. TOXICOLOGICAL SCIENCES
- Marmoset pulmonary cytochrome P450 2F1 oxidizes biphenyl and 7-ethoxycoumarin and hepatic human P450 substrates
- (2017) Shotaro Uehara et al. XENOBIOTICA
- Assessment of the pulmonary CYP1A1 metabolism of mavoglurant (AFQ056) in rat
- (2017) Yildiz Yilmaz et al. XENOBIOTICA
- Co-culture of human alveolar epithelial (hAELVi) and macrophage (THP-1) cell lines
- (2017) Stephanie Kletting ALTEX-Alternatives to Animal Experimentation
- Waterpipe smoking induces epigenetic changes in the small airway epithelium
- (2017) Matthew S. Walters et al. PLoS One
- Xenobiotic metabolism in differentiated human bronchial epithelial cells
- (2016) Jan J. W. A. Boei et al. ARCHIVES OF TOXICOLOGY
- Integrative transcriptomic and protein analysis of human bronchial BEAS-2B exposed to seasonal urban particulate matter
- (2016) Eleonora Longhin et al. ENVIRONMENTAL POLLUTION
- Induction of Flavin-Containing Monooxygenase in Mice by Oral Administration of Phellinus baumii (Agaricomycetes) Extract
- (2016) Batbayar Sainkhuu et al. INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS
- Prevalidation of the ex-vivo model PCLS for prediction of respiratory toxicity
- (2016) A. Hess et al. TOXICOLOGY IN VITRO
- Epithelial-mesenchymal transition and FOXA genes during tobacco smoke carcinogen induced transformation of human bronchial epithelial cells
- (2016) Audun Bersaas et al. TOXICOLOGY IN VITRO
- Characterization of feline cytochrome P450 2B6
- (2016) Gaku Okamatsu et al. XENOBIOTICA
- Microfluidic 3D cell culture: from tools to tissue models
- (2015) Vincent van Duinen et al. CURRENT OPINION IN BIOTECHNOLOGY
- Pulmonary expression of CYP2A13 and ABCB1 is regulated by FOXA2, and their genetic interaction is associated with lung cancer
- (2015) Chan Xiang et al. FASEB JOURNAL
- A lung-on-a-chip array with an integrated bio-inspired respiration mechanism
- (2015) Andreas O. Stucki et al. LAB ON A CHIP
- Organs-on-chips at the frontiers of drug discovery
- (2015) Eric W. Esch et al. NATURE REVIEWS DRUG DISCOVERY
- Impact Assessment of Cigarette Smoke Exposure on Organotypic Bronchial Epithelial Tissue Cultures: A Comparison of Mono-Culture and Coculture Model Containing Fibroblasts
- (2015) Anita R. Iskandar et al. TOXICOLOGICAL SCIENCES
- Targeted omics analyses, and metabolic enzyme activity assays demonstrate maintenance of key mucociliary characteristics in long term cultures of reconstituted human airway epithelia
- (2015) Andrew Baxter et al. TOXICOLOGY IN VITRO
- Activation of the aryl hydrocarbon receptor by carcinogenic aromatic amines and modulatory effects of their N-acetylated metabolites
- (2014) Ludmila Juricek et al. ARCHIVES OF TOXICOLOGY
- Extrahepatic metabolism at the body's internal–external interfaces
- (2014) Ursula Gundert-Remy et al. DRUG METABOLISM REVIEWS
- Analysis of gene expression changes in A549 cells induced by organic compounds from respirable air particles
- (2014) Helena Líbalová et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Differential metabolism of 4-hydroxynonenal in liver, lung and brain of mice and rats
- (2014) Ruijin Zheng et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Bronchial airway gene expression in smokers with lung or head and neck cancer
- (2014) Eric Van Dyck et al. Cancer Medicine
- Combustion derived ultrafine particles induce cytochrome P-450 expression in specific lung compartments in the developing neonatal and adult rat
- (2013) Jackie K. W. Chan et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Metabolism of Styrene to Styrene Oxide and Vinylphenols in Cytochrome P450 2F2- and P450 2E1-Knockout Mouse Liver and Lung Microsomes
- (2013) Shuijie Shen et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Xenobiotic metabolism induction and bulky DNA adducts generated by particulate matter pollution in BEAS-2B cell line: geographical and seasonal influence
- (2013) Capucine Lepers et al. JOURNAL OF APPLIED TOXICOLOGY
- Human iPS cell–derived alveolar epithelium repopulates lung extracellular matrix
- (2013) Mahboobe Ghaedi et al. JOURNAL OF CLINICAL INVESTIGATION
- Proteome-wide Dysregulation by Glucose-6-phosphate Dehydrogenase (G6PD) Reveals a Novel Protective Role for G6PD in Aflatoxin B1-Mediated Cytotoxicity
- (2013) Hsin-Ru Lin et al. JOURNAL OF PROTEOME RESEARCH
- Molecular cloning, sequence characterization, SNP detection, and tissue expression analysis of duck FMO3 gene
- (2013) Peng Wang et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- An improved 3D tetraculture system mimicking the cellular organisation at the alveolar barrier to study the potential toxic effects of particles on the lung
- (2013) Sebastian G Klein et al. Particle and Fibre Toxicology
- Generation of a human airway epithelium derived basal cell line with multipotent differentiation capacity
- (2013) Matthew S Walters et al. RESPIRATORY RESEARCH
- Black cabbage seed extract affects rat Cyp-mediated biotransformation: Organ and sex related differences
- (2012) Donatella Canistro et al. FOOD AND CHEMICAL TOXICOLOGY
- Nrf2-regulated phase II enzymes are induced by chronic ambient nanoparticle exposure in young mice with age-related impairments
- (2012) Hongqiao Zhang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Seasonal influences on CAPs exposures: differential responses in platelet activation, serum cytokines and xenobiotic gene expression
- (2012) Fern Tablin et al. INHALATION TOXICOLOGY
- LOSS ofMrp1alters detoxification enzyme expression in a tissue- and hormonal-status-specific manner
- (2012) Jeffrey C. Sivils et al. JOURNAL OF APPLIED TOXICOLOGY
- Development of humanized steroid and xenobiotic receptor mouse by homologous knock-in of the human steroid and xenobiotic receptor ligand binding domain sequence
- (2012) Katsuhide Igarashi et al. JOURNAL OF TOXICOLOGICAL SCIENCES
- Microengineered physiological biomimicry: Organs-on-Chips
- (2012) Dongeun Huh et al. LAB ON A CHIP
- Maternal intake of quercetin during gestation alters ex vivo benzo[a]pyrene metabolism and DNA adduct formation in adult offspring
- (2012) K. Vanhees et al. MUTAGENESIS
- Mechanisms of toxicity induced by SiO2nanoparticles ofin vitrohuman alveolar barrier: effects on cytokine production, oxidative stress induction, surfactant proteins A mRNA expression and nanoparticles uptake
- (2012) Lucian Romeo Farcal et al. Nanotoxicology
- Differential Distribution of CYP2A6 and CYP2A13 in the Human Respiratory Tract
- (2012) Huai-chih Chiang et al. RESPIRATION
- Induction of carbonyl reductase 1 (CBR1) expression in human lung tissues and lung cancer cells by the cigarette smoke constituent benzo[a]pyrene
- (2012) James L. Kalabus et al. TOXICOLOGY LETTERS
- Up-regulation of cytochrome P450 and phase II enzymes by xenobiotics in precision-cut tissue slices
- (2012) Costas Ioannides XENOBIOTICA
- Dendritic cell functional properties in a three-dimensional tissue model of human lung mucosa
- (2011) Anh Thu Nguyen Hoang et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Xenobiotic metabolism and disposition in human lung: Transcript profiling in non-tumoral and tumoral tissues
- (2011) Julie Leclerc et al. BIOCHIMIE
- Light-dark oscillations in the lung transcriptome: implications for lung homeostasis, repair, metabolism, disease, and drug action
- (2011) Siddharth Sukumaran et al. JOURNAL OF APPLIED PHYSIOLOGY
- Biotransformation enzymes and lung cell response to 2-hydroxyethyl-methacrylate
- (2011) J. T. Samuelsen et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Chemical toxicity testing in vitro using cytochrome P450–expressing cell lines, such as human CYP1B1
- (2011) Robert Landsiedel et al. Nature Protocols
- Inflammatory and cytotoxic responses of an alveolar-capillary coculture model to silica nanoparticles: Comparison with conventional monocultures
- (2011) Jennifer Kasper et al. Particle and Fibre Toxicology
- CYP2F2-generated metabolites, not styrene oxide, are a key event mediating the mode of action of styrene-induced mouse lung tumors
- (2011) G. Cruzan et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Kinetics of Ethylene and Ethylene Oxide in Subcellular Fractions of Lungs and Livers of Male B6C3F1 Mice and Male Fischer 344 Rats and of Human Livers
- (2011) Qiang Li et al. TOXICOLOGICAL SCIENCES
- Tissue Distribution and Gender-Divergent Expression of 78 Cytochrome P450 mRNAs in Mice
- (2011) Helen J. Renaud et al. TOXICOLOGICAL SCIENCES
- Aryl hydrocarbon receptor-mediated Cyp1a1 expression is modulated in a CLOCK-dependent circadian manner
- (2011) Naomi Tanimura et al. TOXICOLOGY
- CYP1A1/1B1 and CYP2A6/2A13 activity is conserved in cultures of differentiated primary human tracheobronchial epithelial cells
- (2011) Nik Newland et al. TOXICOLOGY IN VITRO
- Potential of coculture in vitro models to study inflammatory and sensitizing effects of particles on the lung
- (2011) Sebastian G. Klein et al. TOXICOLOGY IN VITRO
- Fine particulate matter from urban ambient and wildfire sources from California’s San Joaquin Valley initiate differential inflammatory, oxidative stress, and xenobiotic responses in human bronchial epithelial cells
- (2011) L.S. Nakayama Wong et al. TOXICOLOGY IN VITRO
- The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia
- (2010) Alejandro A. Pezzulo et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Human Bronchial Epithelial Cells Differentiate to 3D Glandular Acini on Basement Membrane Matrix
- (2010) Xiaofang Wu et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Role of sulforaphane in the anti-initiating mechanism of lung carcinogenesis in vivo by modulating the metabolic activation and detoxification of benzo(a)pyrene
- (2010) D. Kalpana Deepa Priya et al. BIOMEDICINE & PHARMACOTHERAPY
- 3-Methylindole Metabolites Induce Lung CYP1A1 and CYP2F1 Enzymes by AhR and Non-AhR Mechanisms, Respectively
- (2010) Jessica M. Weems et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Activation of the Acute Inflammatory Response Alters Cytochrome P450 Expression and Eicosanoid Metabolism
- (2010) K. N. Theken et al. DRUG METABOLISM AND DISPOSITION
- A Comparison of Whole Genome Gene Expression Profiles of HepaRG Cells and HepG2 Cells to Primary Human Hepatocytes and Human Liver Tissues
- (2010) S. N. Hart et al. DRUG METABOLISM AND DISPOSITION
- An in vitro triple cell co-culture model with primary cells mimicking the human alveolar epithelial barrier
- (2010) Andrea D. Lehmann et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Inhibitors of human 20α-hydroxysteroid dehydrogenase (AKR1C1)
- (2010) Ossama El-Kabbani et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Up-regulation of cytochrome P450 and phase II enzyme systems in rat precision-cut rat lung slices by the intact glucosinolates, glucoraphanin and glucoerucin
- (2010) Ahmad Faizal Abdull Razis et al. LUNG CANCER
- Reconstituting Organ-Level Lung Functions on a Chip
- (2010) D. Huh et al. SCIENCE
- Cytochromes P4501 (CYP1): Catalytic activities and inducibility by diesel exhaust particle extract and benzo[a]pyrene in intact human lung ex vivo
- (2010) Michael M. Iba et al. TOXICOLOGY
- Persistent induction of cytochrome P450 (CYP)1A enzymes by 3-methylcholanthrene in vivo in mice is mediated by sustained transcriptional activation of the corresponding promoters
- (2009) Weiwu Jiang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Primary human coculture model of alveolo-capillary unit to study mechanisms of injury to peripheral lung
- (2009) Maria Iris Hermanns et al. CELL AND TISSUE RESEARCH
- An impaired alveolar-capillary barrier in vitro: effect of proinflammatory cytokines and consequences on nanocarrier interaction
- (2009) M. I. Hermanns et al. Journal of the Royal Society Interface
- Functional Characterization of Human Cytochrome P450 2S1 Using a Synthetic Gene-Expressed Protein in Escherichia coli
- (2009) P. H. Bui et al. MOLECULAR PHARMACOLOGY
- Mouse specific lung tumors from CYP2F2-mediated cytotoxic metabolism: An endpoint/toxic response where data from multiple chemicals converge to support a mode of action
- (2009) George Cruzan et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Expression and inducibility of CYP1A1, 1A2, 1B1 by β-naphthoflavone and CYP2B22, 3A22, 3A29, 3A46 by rifampicin in the respiratory and olfactory mucosa of pig
- (2009) A. Messina et al. TOXICOLOGY
- Arylamine N-acetyltransferase activity in bronchial epithelial cells and its inhibition by cellular oxidants
- (2009) Julien Dairou et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Expression and variability of microsomal epoxide hydrolase in human lung tissue
- (2009) Ulrike Bernauer et al. TOXICOLOGY LETTERS
- Expression of glutathione S-transferase M2 in stage I/II non-small cell lung cancer and alleviation of DNA damage exposure to benzo[a]pyrene
- (2009) Sheau-Chung Tang et al. TOXICOLOGY LETTERS
- Spectral Monitoring of Surfactant Clearance during Alveolar Epithelial Type II Cell Differentiation
- (2008) Robin J. Swain et al. BIOPHYSICAL JOURNAL
- Carcinogen-Induced Gene Promoter Hypermethylation Is Mediated by DNMT1 and Causal for Transformation of Immortalized Bronchial Epithelial Cells
- (2008) Leah A. Damiani et al. CANCER RESEARCH
- Human Cytochrome P450 2A13 Efficiently Metabolizes Chemicals in Air Pollutants: Naphthalene, Styrene, and Toluene
- (2008) Tatsuki Fukami et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Modulation of rat pulmonary carcinogen-metabolising enzyme systems by the isothiocyanates erucin and sulforaphane
- (2008) Natalya Hanlon et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Structure, Function and Polymorphism of Human Cytosolic Sulfotransferases
- (2008) Yong Li et al. CURRENT DRUG METABOLISM
- Xenobiotic-Induced Transcriptional Regulation of Xenobiotic Metabolizing Enzymes of the Cytochrome P450 Superfamily in Human Extrahepatic Tissues
- (2008) Petr Pavek et al. CURRENT DRUG METABOLISM
- Effect of CYP2A13 Active Site Mutation N297A on Metabolism of Coumarin and Tobacco-Specific Nitrosamines
- (2008) K. E. Schlicht et al. DRUG METABOLISM AND DISPOSITION
- Quantitative Tissue and Gene-Specific Differences and Developmental Changes in Nat1, Nat2, and Nat3 mRNA Expression in the Rat
- (2008) D. F. Barker et al. DRUG METABOLISM AND DISPOSITION
- Expression of UGT1A and UGT2B mRNA in Human Normal Tissues and Various Cell Lines
- (2008) A. Nakamura et al. DRUG METABOLISM AND DISPOSITION
- Co-cultures of multiple cell types mimic pulmonary cell communication in response to urban PM10
- (2008) E. Alfaro-Moreno et al. EUROPEAN RESPIRATORY JOURNAL
- In vitromodels of the human epithelial airway barrier to study the toxic potential of particulate matter
- (2008) Barbara Rothen-Rutishauser et al. Expert Opinion on Drug Metabolism & Toxicology
- Epoxyeicosatrienoic acids and the soluble epoxide hydrolase are determinants of pulmonary artery pressure and the acute hypoxic pulmonary vasoconstrictor response
- (2008) Benjamin Keserü et al. FASEB JOURNAL
- Tissue differences in the modulation of rat cytochromes P450 and phase II conjugation systems by dietary doses of phenethyl isothiocyanate
- (2008) N. Konsue et al. FOOD AND CHEMICAL TOXICOLOGY
- Alteration of xenobiotic metabolizing enzymes by resveratrol in liver and lung of CD1 mice
- (2008) D. Canistro et al. FOOD AND CHEMICAL TOXICOLOGY
- Cigarette smoking and subsequent risk of lung cancer in men and women: analysis of a prospective cohort study
- (2008) Neal D Freedman et al. LANCET ONCOLOGY
- Up-regulation of the glutathione S-transferase system in human liver by polycyclic aromatic hydrocarbons; comparison with rat liver and lung
- (2008) D. S. Pushparajah et al. MUTAGENESIS
- Differential response of human and rat epoxide hydrolase to polycyclic aromatic hydrocarbon exposure: Studies using precision-cut tissue slices
- (2008) Daphnee S. Pushparajah et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Combined effect of protein kinase B inhibitor or extracellular signal-regulated kinase inhibitor against farnesyltransferase inhibition-induced apoptosis in SiHa cells
- (2008) Sun Joo Lee et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Critical appraisal of the expression of cytochrome P450 enzymes in human lung and evaluation of the possibility that such expression provides evidence of potential styrene tumorigenicity in humans
- (2008) Gary P. Carlson TOXICOLOGY
- Expression and induction by rifampicin of CAR- and PXR-regulated CYP2B and CYP3A in liver, kidney and airways of pig
- (2008) Annalisa Nannelli et al. TOXICOLOGY
- Purification, molecular cloning, heterologous expression and characterization of pig CYP1A2
- (2008) A. Messina et al. XENOBIOTICA
- Pharmacogenetics of Intestinal Absorption
- (2008) Tsutomu Nakamura et al. Current Drug Delivery
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started