N‐Heterocyclic Carbene‐Catalyzed β ‐Indolylation of α ‐Bromoenals with Indoles

NHC-Catalyzed Generation of α,β-Unsaturated Acylazoliums for the Enantioselective Synthesis of Heterocycles and Carbocycles

(2019) Santigopal Mondal et al.   ACCOUNTS OF CHEMICAL RESEARCH

Direct and Enantioselective Synthesis of N−H-Free 1,5-Benzodiazepin-2-ones by an N-Heterocyclic Carbene Catalyzed [3+4] Annulation Reaction

(2018) Chao Fang et al.   CHEMISTRY-A EUROPEAN JOURNAL

N-Heterocyclic Carbene-Catalyzed Enantioselective β-Amination of α-Bromoenals Enabled by a Proton-Shuttling Strategy

(2018) Ming Lang et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

N-Heterocyclic Carbene-Catalyzed Michael–Michael–Lactonization Cascade for the Enantioselective Synthesis of Tricyclic δ-Lactones

(2018) Subrata Mukherjee et al.   ORGANIC LETTERS

N-Heterocyclic Carbene-Catalyzed Enantioselective Synthesis of Spiro-glutarimides via α,β-Unsaturated Acylazoliums

(2018) Santigopal Mondal et al.   ORGANIC LETTERS

Carbene-catalyzed enantioselective oxidative coupling of enals and di(hetero)arylmethanes

(2018) Qiao Chen et al.   Chemical Science

Carbene-Catalyzed Enantioselective Addition of Benzylic Carbon to Unsaturated Acyl Azolium for Rapid Synthesis of Pyrrolo[3,2-c]quinolines

(2018) Jilan Wang et al.   ACS Catalysis

N-Heterocyclic Carbene Catalyzed Quadruple Domino Reactions: Asymmetric Synthesis of Cyclopenta[c ]chromenones

(2018) Qiang Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

(Dynamic) Kinetic Resolution of Enamines/Imines: Enantioselective N-Heterocyclic Carbene Catalyzed [3+3] Annulation of Bromoenals and Enamines/Imines

(2018) Kun-Quan Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Participation of β-Ketothioamides in N-Heterocyclic Carbene-Catalyzed [3 + 3] Spiroannulation: Asymmetric Synthesis of Functionalized Spiro-piperidinone Derivatives

(2018) Hong Lu et al.   JOURNAL OF ORGANIC CHEMISTRY

Stereoselective Synthesis of Functionalized Tetrahydro-1H-1,2-diazepines by N-Heterocyclic Carbene-Catalyzed [3 + 4] Annulation

(2017) Shi-Ya Zhu et al.   ORGANIC LETTERS

Formal [3 + 4] Annulation of α,β-Unsaturated Acyl Azoliums: Access to Enantioenriched N–H-Free 1,5-Benzothiazepines

(2017) Chao Fang et al.   ORGANIC LETTERS

Direct Activation of β-sp3-Carbons of Saturated Carboxylic Esters as Electrophilic Carbons via Oxidative Carbene Catalysis

(2017) Bin Liu et al.   ORGANIC LETTERS

N-Heterocyclic carbene-catalyzed oxidative [3 + 2] annulation of dioxindoles and enals: cross coupling of homoenolate and enolate

(2017) Xiang-Yu Chen et al.   Chemical Science

N-Heterocyclic Carbene Catalysis via the α,β-Unsaturated Acyl Azolium

(2017) Changhe Zhang et al.   ACS Catalysis

Enantioselective Nucleophilic β-Carbon-Atom Amination of Enals: Carbene-Catalyzed Formal [3+2] Reactions

(2016) Xingxing Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cooperative Catalysis and Activation with N-Heterocyclic Carbenes

(2016) Michael H. Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances in N-heterocyclic carbene (NHC)-catalysed benzoin reactions

(2016) Rajeev S Menon et al.   Beilstein Journal of Organic Chemistry

N-Heterocyclic carbene-catalyzed [3 + 2] annulation of bromoenals with 3-aminooxindoles: highly enantioselective synthesis of spirocyclic oxindolo-γ-lactams

(2016) Kun-Quan Chen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective Intramolecular Hydroacylation of Unactivated Alkenes: An NHC-Catalyzed Robust and Versatile Formation of Cyclic Chiral Ketones

(2015) Daniel Janssen-Müller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of Spirocyclohexadienones by NHC-Catalyzed Formal [3+3] Annulation Reaction of Enals

(2015) Santhivardhana Reddy Yetra et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes

(2015) Darrin M. Flanigan et al.   CHEMICAL REVIEWS

Recent advances in employing homoenolates generated by N-heterocyclic carbene (NHC) catalysis in carbon–carbon bond-forming reactions

(2015) Rajeev S. Menon et al.   CHEMICAL SOCIETY REVIEWS

Benzimidazole–ibuprofen/mesalamine conjugates: Potential candidates for multifactorial diseases

(2015) Yogita Bansal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

N-Heterocyclic Carbene-Catalyzed Formal [3 + 2] Annulation of α-Bromoenals with 3-Aminooxindoles: A Stereoselective Synthesis of Spirooxindole γ-Butyrolactams

(2015) Delu Jiang et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Synthesis of Functionalized Pyrazoles by NHC-Catalyzed Reaction of Pyrazolones with α,β-Unsaturated Aldehydes

(2015) Santhivardhana Reddy Yetra et al.   ORGANIC LETTERS

Synthesis of functionalized γ-lactones via a three-component cascade reaction catalyzed by consecutive N-heterocyclic carbene systems

(2015) Qian Zhao et al.   RSC Advances

On the Mechanism of N-Heterocyclic Carbene-Catalyzed Reactions Involving Acyl Azoliums

(2014) Jessada Mahatthananchai et al.   ACCOUNTS OF CHEMICAL RESEARCH

Oxidative Enantioselective α-Fluorination of Aliphatic Aldehydes Enabled by N-Heterocyclic Carbene Catalysis

(2014) Fangyi Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene Catalyzed Formal [3+2] Annulation Reaction of Enals: An Efficient Enantioselective Access to Spiro-Heterocycles

(2014) Chang Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene Catalyzed Cyclocondensation of α,β-Unsaturated Carboxylic Acids: Enantioselective Synthesis of Pyrrolidinone and Dihydropyridinone Derivatives

(2014) Xiang-Yu Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ipragliflozin: First Global Approval

(2014) Raewyn M. Poole et al.   DRUGS

N-Heterocyclic Carbene Catalyzed Switchable Reactions of Enals with Azoalkenes: Formal [4 + 3] and [4 + 1] Annulations for the Synthesis of 1,2-Diazepines and Pyrazoles

(2014) Chang Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An overview of N-heterocyclic carbenes

(2014) Matthew N. Hopkinson et al.   NATURE

N-Heterocyclic Carbene-Catalyzed Annulations of Enals and Ynals with Indolin-3-ones: Synthesis of 3,4-Dihydropyrano[3,2-b]indol-2-ones

(2013) Yingyan Lu et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective N-Heterocyclic Carbene-Catalyzed Annulations of 2-Bromoenals with 1,3-Dicarbonyl Compounds and EnaminesviaChiral α,β-Unsaturated Acylazoliums

(2013) Santhivardhana Reddy Yetra et al.   ADVANCED SYNTHESIS & CATALYSIS

Diaminocyclopropenylidene Organocatalysts: Beyond N-Heterocyclic Carbenes

(2013) Stephen J. Connon   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct β-Activation of Saturated Aldehydes to Formal Michael Acceptors through Oxidative NHC Catalysis

(2013) Junming Mo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NHC Organocatalytic Formal LUMO Activation of α,β-Unsaturated Esters for Reaction with Enamides

(2013) Jiajia Cheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Acyl anion free N-heterocyclic carbene organocatalysis

(2013) Sarah J. Ryan et al.   CHEMICAL SOCIETY REVIEWS

Asymmetric N-Heterocyclic Carbene Catalyzed Addition of Enals to Nitroalkenes: Controlling Stereochemistry via the Homoenolate Reactivity Pathway To Access δ-Lactams

(2013) Nicholas A. White et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric N-Heterocyclic Carbene (NHC)-Catalyzed Annulation of Modified Enals with Enolizable Aldehydes

(2013) Santhivardhana Reddy Yetra et al.   ORGANIC LETTERS

Enantioselective, NHC-Catalyzed Annulations of Trisubstituted Enals and CyclicN-Sulfonylimines via α,β-Unsaturated Acyl Azoliums

(2012) Alberto G. Kravina et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic umpolung: N-heterocyclic carbenes and beyond

(2012) Xavier Bugaut et al.   CHEMICAL SOCIETY REVIEWS

Direct α-Functionalization of Simple Aldehydes via Oxidative N-Heterocyclic Carbene Catalysis

(2012) Junming Mo et al.   ORGANIC LETTERS

N-Heterocyclic Carbene-Catalyzed Annulation of α-Cyano-1,4-diketones with Ynals

(2012) Fedor Romanov-Michailidis et al.   ORGANIC LETTERS

Chiral N-Heterocyclic Carbene-Catalyzed Annulations of Enals and Ynals with Stable Enols: A Highly Enantioselective Coates–Claisen Rearrangement

(2012) Jessada Mahatthananchai et al.   ACS Catalysis

Extending NHC-Catalysis: Coupling Aldehydes with Unconventional Reaction Partners

(2011) Akkattu T. Biju et al.   ACCOUNTS OF CHEMICAL RESEARCH

N-Heterocyclic Carbene-Catalyzed Enantioselective Annulation of Bromoenal and 1,3-Dicarbonyl Compounds

(2011) Fang-Gang Sun et al.   ADVANCED SYNTHESIS & CATALYSIS

N-Heterocyclic Carbene Catalyzed Domino Reactions

(2011) André Grossmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene Catalysis: Enantioselective Formal [2+2] Cycloaddition of Ketenes and N-Sulfinylanilines

(2011) Teng-Yue Jian et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of Dihydropyridinones via NHC-Catalyzed Aza-Claisen Reaction

(2011) Benedikt Wanner et al.   ORGANIC LETTERS

EnantioselectiveN-Heterocyclic Carbene-Catalyzed Michael Addition to α,β-Unsaturated Aldehydes by Redox Oxidation

(2011) Zi-Qiang Rong et al.   ORGANIC LETTERS

Cooperative Lewis acid/N-heterocyclic carbene catalysis

(2011) Daniel T. Cohen et al.   Chemical Science

NHC-Catalyzed Michael Addition to α,β-Unsaturated Aldehydes by Redox Activation

(2010) Suman De Sarkar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Enantioselective Claisen Rearrangement Catalyzed by N-Heterocyclic Carbenes

(2010) Juthanat Kaeobamrung et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Enantioselective Total Syntheses of Bakkenolides I, J, and S: Application of a Carbene-Catalyzed Desymmetrization

(2010) Eric M. Phillips et al.   ORGANIC LETTERS

N-Heterocyclic Carbene-Catalyzed Generation of α,β-Unsaturated Acyl Imidazoliums: Synthesis of Dihydropyranones by their Reaction with Enolates

(2009) Sarah J. Ryan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral N-Heterocyclic Carbene Catalyzed Staudinger Reaction of Ketenes with Imines:  Highly Enantioselective Synthesis ofN-Boc β-Lactams

(2007) Yan-Rong Zhang et al.   ORGANIC LETTERS