New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells

GRASP55 and UPR Control Interleukin-1β Aggregation and Secretion

(2019) Marioara Chiritoiu et al.   DEVELOPMENTAL CELL

A GBF1-Dependent Mechanism for Environmentally Responsive Regulation of ER-Golgi Transport

(2019) Mafalda Lopes-da-Silva et al.   DEVELOPMENTAL CELL

A mechanism for differential sorting of the planar cell polarity proteins Frizzled6 and Vangl2 at thetrans-Golgi network

(2018) Tianji Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrated design, execution, and analysis of arrayed and pooled CRISPR genome-editing experiments

(2018) Matthew C Canver et al.   Nature Protocols

Unconventional protein secretion triggered by nutrient starvation

(2018) David Cruz-Garcia et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Subcellular Organization of GPCR Signaling

(2018) Kelsie Eichel et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

TANGO1 builds a machine for collagen export by recruiting and spatially organizing COPII, tethers and membranes

(2018) Ishier Raote et al.   eLife

Here, there, and everywhere: The importance of ER membrane contact sites

(2018) Haoxi Wu et al.   SCIENCE

The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1

(2018) Sam A Menzies et al.   eLife

Unconventional secretion of FABP4 by endosomes and secretory lysosomes

(2017) Julien Villeneuve et al.   JOURNAL OF CELL BIOLOGY

A genome-wide CRISPR screen reconciles the role of N-linked glycosylation in galectin-3 transport to the cell surface

(2017) Sarah E. Stewart et al.   JOURNAL OF CELL SCIENCE

Architecture of the human interactome defines protein communities and disease networks

(2017) Edward L. Huttlin et al.   NATURE

Applying systems-level spectral imaging and analysis to reveal the organelle interactome

(2017) Alex M. Valm et al.   NATURE

Sphingomyelin metabolism controls the shape and function of the Golgi cisternae

(2017) Felix Campelo et al.   eLife

CellProfiler Analyst: interactive data exploration, analysis and classification of large biological image sets

(2016) David Dao et al.   BIOINFORMATICS

Signaling at the Golgi: sensing and controlling the membrane fluxes

(2016) Alberto Luini et al.   CURRENT OPINION IN CELL BIOLOGY

A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors

(2016) Ryan J Park et al.   NATURE GENETICS

Ribosome-associated protein quality control

(2016) Onn Brandman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ribosome-associated protein quality control

(2016) Onn Brandman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation

(2016) Max A Horlbeck et al.   eLife

Nucleosomes impede Cas9 access to DNA in vivo and in vitro

(2016) Max A Horlbeck et al.   eLife

The Pathway of Collagen Secretion

(2015) Vivek Malhotra et al.   Annual Review of Cell and Developmental Biology

A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks

(2015) Oren Parnas et al.   CELL

The BioPlex Network: A Systematic Exploration of the Human Interactome

(2015) Edward L. Huttlin et al.   CELL

High-throughput functional genomics using CRISPR–Cas9

(2015) Ophir Shalem et al.   NATURE REVIEWS GENETICS

The Pfam protein families database: towards a more sustainable future

(2015) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Structure of the Sec61 channel opened by a signal sequence

(2015) R. M. Voorhees et al.   SCIENCE

Protein Sorting at the trans-Golgi Network

(2014) Yusong Guo et al.   Annual Review of Cell and Developmental Biology

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

(2014) Luke A. Gilbert et al.   CELL

Control Systems of Membrane Transport at the Interface between the Endoplasmic Reticulum and the Golgi

(2014) Jorge Cancino et al.   DEVELOPMENTAL CELL

Sphingomyelin homeostasis is required to form functional enzymatic domains at the trans-Golgi network

(2014) Josse van Galen et al.   JOURNAL OF CELL BIOLOGY

The specificity of vesicle traffic to the Golgi is encoded in the golgin coiled-coil proteins

(2014) M. Wong et al.   SCIENCE

CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

(2013) Luke A. Gilbert et al.   CELL

Unconventional Secretion, Unconventional Solutions

(2013) M. Zhang et al.   SCIENCE

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

RNAi screening reveals a large signaling network controlling the Golgi apparatus in human cells

(2012) Joanne Chia et al.   Molecular Systems Biology

Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway

(2012) Jeremy C. Simpson et al.   NATURE CELL BIOLOGY

COPII and the regulation of protein sorting in mammals

(2011) Giulia Zanetti et al.   NATURE CELL BIOLOGY

Entry and Exit Mechanisms at the cis-Face of the Golgi Complex

(2011) A. Lorente-Rodriguez et al.   Cold Spring Harbor Perspectives in Biology

At the junction of SNARE and SM protein function

(2010) Chavela M Carr et al.   CURRENT OPINION IN CELL BIOLOGY

RNAi screen identifies a role for adaptor protein AP-3 in sorting to the regulated secretory pathway

(2010) Cédric S. Asensio et al.   JOURNAL OF CELL BIOLOGY

USP32 is an active, membrane-bound ubiquitin protease overexpressed in breast cancers

(2010) Shiva Akhavantabasi et al.   MAMMALIAN GENOME

Pathways for Cytokine Secretion

(2010) Amanda C. Stanley et al.   PHYSIOLOGY

TANGO1 Facilitates Cargo Loading at Endoplasmic Reticulum Exit Sites

(2009) Kota Saito et al.   CELL

A genome-wide RNA interference screen identifies two novel components of the metazoan secretory pathway

(2009) Franz Wendler et al.   EMBO JOURNAL

Actin remodeling by ADF/cofilin is required for cargo sorting at the trans-Golgi network

(2009) Julia von Blume et al.   JOURNAL OF CELL BIOLOGY

Labyrinthitis ossificans: How accurate is MRI in predicting cochlear obstruction?

(2009) Brandon Isaacson et al.   OTOLARYNGOLOGY-HEAD AND NECK SURGERY

Sorting in early endosomes reveals connections to docking- and fusion-associated factors

(2009) S. V. Barysch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tracing the Retrograde Route in Protein Trafficking

(2008) Ludger Johannes et al.   CELL