期刊
CURRENT OPINION IN CELL BIOLOGY
卷 39, 期 -, 页码 37-42出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2016.01.014
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资金
- FFC (Italian Cystic Fibrosis Research Foundation FFC) [2 2014]
- MIUR (COSM Progetto Interomics)
- Fondazione Telethon
- AIRC (Italian Association for Cancer Research) the MIUR Project FaReBio di Qualita [IG 15767]
- PON [01/00117, 01-00862, PONa3-00025]
- PNR-CNR Aging Program
- Progetto Bandiera 'Epigen'
Over the past few decades, it has emerged that the Golgi (and other secretory stations) is host to a variety of signaling molecules and can act as a signaling hub that receives, emits and elaborates signals. This endomembrane-based signaling apparatus appears to have more than one purpose. Its most fundamental function appears to be the auto-regulation of the biosynthetic apparatus to maintain and/or optimize its own activities and to coordinate such activities with those of other cellular modules. 1 This is achieved by dedicated control devices that provide stability, robustness, precision, sensitivity and complexity to cellular behaviors.
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