Protodioscin protects PC12 cells against oxygen and glucose deprivation-induced injury through miR-124/AKT/Nrf2 pathway

Antioxidant effects of ginkgolides and bilobalide against cerebral ischemia injury by activating the Akt/Nrf2 pathway in vitro and in vivo

(2019) Qiu Liu et al.   CELL STRESS & CHAPERONES

Diterpene ginkgolides protect against cerebral ischemia/reperfusion damage in rats by activating Nrf2 and CREB through PI3K/Akt signaling

(2018) Wen Zhang et al.   ACTA PHARMACOLOGICA SINICA

Long non-coding RNA GAS5 aggravates hypoxia injury in PC-12 cells via down-regulating miR-124

(2018) Xiaoli Hu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Metformin protects PC12 cells against oxygen-glucose deprivation/reperfusion injury

(2018) Elnaz Mohammad Alizadeh et al.   TOXICOLOGY MECHANISMS AND METHODS

Metformin protects PC12 cells against oxygen-glucose deprivation/reperfusion injury

(2018) Elnaz Mohammad Alizadeh et al.   TOXICOLOGY MECHANISMS AND METHODS

Ginsenoside Rg1 protects against ischemic/reperfusion-induced neuronal injury through miR-144/Nrf2/ARE pathway

(2018) Shi-feng Chu et al.   ACTA PHARMACOLOGICA SINICA

Dynamic Changes in miR-124 levels in Patients with Acute Cerebral Infarction

(2018) Mei Sun et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Oxidative stress-induced miRNAs modulate AKT signaling and promote cellular senescence in uterine leiomyoma

(2018) Xiuhua Xu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Wentilactone A induces cell apoptosis by targeting AKR1C1 gene via the IGF‑1R/IRS1/PI3K/AKT/Nrf2/FLIP/Caspase‑3 signaling pathway in small cell lung cancer

(2018) Wenli Jiang et al.   Oncology Letters

Brain-derived neurotrophic factor inhibits hyperglycemia-induced apoptosis and downregulation of synaptic plasticity-related proteins in hippocampal neurons via the PI3K/Akt pathway

(2018) Yuan Zhong et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Baicalin alleviates hyperglycemia-induced endothelial impairment via Nrf2

(2018) Gen Chen et al.   JOURNAL OF ENDOCRINOLOGY

Panax notoginseng Saponins Protect Cerebral Microvascular Endothelial Cells against Oxygen-Glucose Deprivation/Reperfusion-Induced Barrier Dysfunction via Activation of PI3K/Akt/Nrf2 Antioxidant Signaling Pathway

(2018) Shaonan Hu et al.   MOLECULES

Nrf2 Signaling Elicits a Neuroprotective Role Against PFOS-mediated Oxidative Damage and Apoptosis

(2018) Pingping Sun et al.   NEUROCHEMICAL RESEARCH

Akt-mediated platelet apoptosis and its therapeutic implications in immune thrombocytopenia

(2018) Mengxing Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroprotective mechanisms of miR-124 activating PI3K/Akt signaling pathway in ischemic stroke

(2017) Changming Wang et al.   Experimental and Therapeutic Medicine

Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonin's neuroprotective activity after focal cerebral ischemia in mice

(2017) Ulkan Kilic et al.   Redox Biology

MiRNA-124 induces neuroprotection and functional improvement after focal cerebral ischemia

(2016) Somayyeh Hamzei Taj et al.   BIOMATERIALS

Nrf2—a Promising Therapeutic Target for Defensing Against Oxidative Stress in Stroke

(2016) Rongrong Zhang et al.   MOLECULAR NEUROBIOLOGY

Extracellular HSP70 levels in diabetic environment in rats

(2015) T. M. M. Santos et al.   CELL STRESS & CHAPERONES

The Effect of Pre-Condition Cerebella Fastigial Nucleus Electrical Stimulation within and beyond the Time Window of Thrombolytic on Ischemic Stroke in the Rats

(2015) Weiju Tang et al.   PLoS One

Regulatory Mechanism of Endothelin Receptor B in the Cerebral Arteries after Focal Cerebral Ischemia

(2014) Anne-Sofie Grell et al.   PLoS One

Evaluation of the Protective Potential of Brain Microvascular Endothelial Cell Autophagy on Blood–Brain Barrier Integrity During Experimental Cerebral Ischemia–Reperfusion Injury

(2014) Haiying Li et al.   Translational Stroke Research

MicroRNA-124 Protects Neurons Against Apoptosis in Cerebral Ischemic Stroke

(2013) Yang Sun et al.   CNS Neuroscience & Therapeutics

MicroRNA-124–Mediated Regulation of Inhibitory Member of Apoptosis-Stimulating Protein of p53 Family in Experimental Stroke

(2013) Xiangrong Liu et al.   STROKE

Roles of Oxidative Stress, Apoptosis, PGC-1α and Mitochondrial Biogenesis in Cerebral Ischemia

(2011) Shang-Der Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Nrf2–Keap1 cellular defense pathway and heat shock protein 70 (Hsp70) response. Role in protection against oxidative stress in early neonatal unilateral ureteral obstruction (UUO)

(2010) Martin E. Rinaldi Tosi et al.   CELL STRESS & CHAPERONES

Ultrasonic and fermented pretreatment technology for diosgenin production from Diosorea zingiberensis C.H. Wright

(2010) Linli Qiu et al.   CHEMICAL ENGINEERING RESEARCH & DESIGN

Overexpression of Heme Oxygenase-1 Is Neuroprotective in a Model of Permanent Middle Cerebral Artery Occlusion in Transgenic Mice

(2010) Nariman Panahian et al.   JOURNAL OF NEUROCHEMISTRY

Ethanolic Extract of Propolis Augments TRAIL-Induced Apoptotic Death in Prostate Cancer Cells

(2009) Ewelina Szliszka et al.   Evidence-based Complementary and Alternative Medicine

miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche

(2009) Li-Chun Cheng et al.   NATURE NEUROSCIENCE

Endoplasmic reticulum in the penumbra following middle cerebral artery occlusion in the rabbit

(2009) Huai-jun Liu et al.   NEUROLOGICAL SCIENCES

Headache associated with ischemic cerebrovascular disease

(2008) H.C. Diener et al.   REVUE NEUROLOGIQUE

Posttranscriptional control of neuronal development by microRNA networks

(2007) Fen-Biao Gao   TRENDS IN NEUROSCIENCES