Roles of Oxidative Stress, Apoptosis, PGC-1α and Mitochondrial Biogenesis in Cerebral Ischemia

Vascular PPARδ Protects Against Stroke-Induced Brain Injury

(2011) Ke-Jie Yin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Complex I syndrome in myocardial stunning and the effect of adenosine

(2011) Laura B. Valdez et al.   FREE RADICAL BIOLOGY AND MEDICINE

In vivo Contributions of BH3-Only Proteins to Neuronal Death Following Seizures, Ischemia, and Traumatic Brain Injury

(2011) Tobias Engel et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Oxidative Stress and Hypoxia Contribute to Alzheimer's Disease Pathogenesis: Two Sides of the Same Coin

(2011) Michela Guglielmotto et al.   TheScientificWorldJOURNAL

Redox Regulation of the Intrinsic Pathway in Neuronal Apoptosis

(2010) James L. Franklin   ANTIOXIDANTS & REDOX SIGNALING

The potential role of mitochondrial dysfunction in seizure-associated cell death in the hippocampus and epileptogenesis

(2010) Shang-Der Chen et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Peroxisome Proliferator-Activated Receptor   Regulation of miR-15a in Ischemia-Induced Cerebral Vascular Endothelial Injury

(2010) K. J. Yin et al.   JOURNAL OF NEUROSCIENCE

Activation of calcium/calmodulin-dependent protein kinase IV and peroxisome proliferator-activated receptor γ coactivator-1α signaling pathway protects against neuronal injury and promotes mitochondrial biogenesis in the hippocampal CA1 subfield after tra

(2010) Shang-Der Chen et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Anti-apoptotic Actions of PPAR-γ Against Ischemic Stroke

(2010) Wen-Hsuan Fong et al.   MOLECULAR NEUROBIOLOGY

Redox Reactions Induced by Nitrosative Stress Mediate Protein Misfolding and Mitochondrial Dysfunction in Neurodegenerative Diseases

(2010) Zezong Gu et al.   MOLECULAR NEUROBIOLOGY

The Science of Stroke: Mechanisms in Search of Treatments

(2010) Michael A. Moskowitz et al.   NEURON

Neuronal caspase-3 and PARP-1 correlate differentially with apoptosis and necrosis in ischemic human stroke

(2009) Tiina Sairanen et al.   ACTA NEUROPATHOLOGICA

Mitochondrial and apoptotic neuronal death signaling pathways in cerebral ischemia

(2009) Kuniyasu Niizuma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Ligand-Activated Peroxisome Proliferator–Activated Receptor-γ Protects Against Ischemic Cerebral Infarction and Neuronal Apoptosis by 14-3-3ε Upregulation

(2009) Jui-Sheng Wu et al.   CIRCULATION

Mitochondrial Nitric Oxide Synthase: A Masterpiece of Metabolic Adaptation, Cell Growth, Transformation, and Death

(2009) Paola V. Finocchietto et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

PGC-1α and PGC-1β Regulate Mitochondrial Density in Neurons

(2009) Przemyslaw Wareski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative stress and mitochondrial dysfunction as determinants of ischemic neuronal death and survival

(2009) Kuniyasu Niizuma et al.   JOURNAL OF NEUROCHEMISTRY

Apoptotic Mechanisms After Cerebral Ischemia

(2009) Brad R.S. Broughton et al.   STROKE

Mitochondrial Targets for Stroke

(2009) Peter S. Vosler et al.   STROKE

Mitochondrial nitric oxide synthase, mitochondrial brain dysfunction in aging, and mitochondria-targeted antioxidants☆

(2008) Ana Navarro et al.   ADVANCED DRUG DELIVERY REVIEWS

Mitochondrial biogenesis and turnover

(2008) F DIAZ et al.   CELL CALCIUM

Isoflurane preconditioning increases B-cell lymphoma-2 expression and reduces cytochrome c release from the mitochondria in the ischemic penumbra of rat brain

(2008) Liaoliao Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Overexpression of UCP2 Protects Thalamic Neurons following Global Ischemia in the Mouse

(2008) Tomas Deierborg Olsson et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Transient Hypoxia Stimulates Mitochondrial Biogenesis in Brain Subcortex by a Neuronal Nitric Oxide Synthase-Dependent Mechanism

(2008) D. R. Gutsaeva et al.   JOURNAL OF NEUROSCIENCE

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α

(2008) Zoltan Arany et al.   NATURE

Transcriptional Paradigms in Mammalian Mitochondrial Biogenesis and Function

(2008) Richard C. Scarpulla   PHYSIOLOGICAL REVIEWS

Exploiting endogenous anti-apoptotic proteins for novel therapeutic strategies in cerebral ischemia

(2008) A RAMI et al.   PROGRESS IN NEUROBIOLOGY

Rapidly Increased Neuronal Mitochondrial Biogenesis After Hypoxic-Ischemic Brain Injury

(2008) Wei Yin et al.   STROKE

Potential Role of PUMA in Delayed Death of Hippocampal CA1 Neurons After Transient Global Cerebral Ischemia

(2008) Kuniyasu Niizuma et al.   STROKE