Important regulatory function of transient receptor potential ankyrin 1 receptors in age-related learning and memory alterations of mice

The effects of aerobic exercise on depression-like, anxiety-like, and cognition-like behaviours over the healthy adult lifespan of C57BL/6 mice

(2018) Julie A. Morgan et al.   BEHAVIOURAL BRAIN RESEARCH

Transient receptor potential ankyrin 1 channels are involved in spontaneous peptide hormone release from astrocytes

(2018) Mai Takizawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TRP Channels as Novel Targets for Endogenous Ligands: Focus on Endocannabinoids and Nociceptive Signalling

(2018) Maksim V. Storozhuk et al.   Current Neuropharmacology

The Role of Endothelial Ca2+ Signaling in Neurovascular Coupling: A View from the Lumen

(2018) Germano Guerra et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Behavioural alterations and morphological changes are attenuated by the lack of TRPA1 receptors in the cuprizone-induced demyelination model in mice

(2018) Kata Bölcskei et al.   JOURNAL OF NEUROIMMUNOLOGY

Skin neurogenic inflammation

(2018) Jae Eun Choi et al.   Seminars in Immunopathology

Doxorubicin-induced elevated oxidative stress and neurochemical alterations in brain and cognitive decline: protection by MESNA and insights into mechanisms of chemotherapy-induced cognitive impairment (“chemobrain”)

(2018) Jeriel T.R. Keeney et al.   Oncotarget

Mitochondria and Calcium Regulation as Basis of Neurodegeneration Associated With Aging

(2018) Marioly Müller et al.   Frontiers in Neuroscience

Factors that positively or negatively mediate the effects of age on working memory across the adult life span

(2018) Selene Cansino et al.   GeroScience

Time and the Metrics of Aging

(2018) Luigi Ferrucci et al.   CIRCULATION RESEARCH

Novel Object Recognition as a Facile Behavior Test for Evaluating Drug Effects in AβPP/PS1 Alzheimer's Disease Mouse Model

(2018) Ru Zhang et al.   JOURNAL OF ALZHEIMERS DISEASE

Neuroprotective effects of TRPA1 channels in the cerebral endothelium following ischemic stroke

(2018) Paulo Wagner Pires et al.   eLife

A novel high-throughput assay for respiration in isolated brain microvessels reveals impaired mitochondrial function in the aged mice

(2018) Venkata N. Sure et al.   GeroScience

Effects of sulfide and polysulfides transmitted by direct or signal transduction-mediated activation of TRPA1 channels

(2018) Gábor Pozsgai et al.   BRITISH JOURNAL OF PHARMACOLOGY

TRPA1 - a molecular view

(2018) Jannis E Meents et al.   JOURNAL OF NEUROPHYSIOLOGY

Antioxidant and Oxidative Stress: A Mutual Interplay in Age-Related Diseases

(2018) Bee Ling Tan et al.   Frontiers in Pharmacology

PACAP deficiency as a model of aging

(2018) D. Reglodi et al.   GeroScience

Increased Hippocampal ProBDNF Contributes to Memory Impairments in Aged Mice

(2017) Mona Buhusi et al.   Frontiers in Aging Neuroscience

TRPA1 expression and its functional activation in rodent cortex

(2017) Ehsan Kheradpezhouh et al.   Open Biology

Cognitive and behavioral evaluation of nutritional interventions in rodent models of brain aging and dementia

(2017) Devin Wahl et al.   Clinical Interventions in Aging

Multimodal physical activity increases brain-derived neurotrophic factor levels and improves cognition in institutionalized older women

(2017) Kelem Vedovelli et al.   GeroScience

The Oxygen Paradox, the French Paradox, and age-related diseases

(2017) Joanna M. S. Davies et al.   GeroScience

IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan

(2017) Nicole M. Ashpole et al.   GeroScience

Age-related changes in central effects of corticotropin-releasing factor (CRF) suggest a role for this mediator in aging anorexia and cachexia

(2017) Judit Tenk et al.   GeroScience

Connective tissue growth factor (CTGF) in age-related vascular pathologies

(2017) Zoltan Ungvari et al.   GeroScience

Differential effects of early-life nutrient restriction in long-lived GHR-KO and normal mice

(2017) Yimin Fang et al.   GeroScience

TRPA1 deficiency is protective in cuprizone-induced demyelination-A new target against oligodendrocyte apoptosis

(2016) Éva Sághy et al.   GLIA

Role of transient receptor potential ankyrin 1 channels in Alzheimer’s disease

(2016) Kuan-I Lee et al.   Journal of Neuroinflammation

Loss of Transient Receptor Potential Ankyrin 1 Channel Deregulates Emotion, Learning and Memory, Cognition, and Social Behavior in Mice

(2016) Kuan-I Lee et al.   MOLECULAR NEUROBIOLOGY

Proton-gated Ca2+-permeable TRP channels damage myelin in conditions mimicking ischaemia

(2016) Nicola B. Hamilton et al.   NATURE

Gradual Carotid Artery Stenosis in Mice Closely Replicates Hypoperfusive Vascular Dementia in Humans

(2016) Yorito Hattori et al.   Journal of the American Heart Association

TRPA1 as a drug target—promise and challenges

(2015) Jun Chen et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Cause-of-Death Analysis in Rodent Aging Studies

(2015) J. M. Snyder et al.   VETERINARY PATHOLOGY

Characterization of Aldh2 -/- mice as an age-related model of cognitive impairment and Alzheimer’s disease

(2015) Yohan D’Souza et al.   Molecular Brain

Animal Models of Aging Research: Implications for Human Aging and Age-Related Diseases

(2015) Sarah J. Mitchell et al.   Annual Review of Animal Biosciences

Quality of life in dementia: a systematically conducted narrative review of dementia-specific measurement scales

(2014) Ann Bowling et al.   AGING & MENTAL HEALTH

Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases

(2014) C. Franceschi et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Contribution of Transient Receptor Potential Ankyrin 1 to Chronic Pain in Aged Mice With Complete Freund's Adjuvant-Induced Arthritis

(2014) Sheldon R. Garrison et al.   Arthritis & Rheumatology

TRPA1: A Transducer and Amplifier of Pain and Inflammation

(2013) Ari Koivisto et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Spatial memory tasks in rodents: what do they model?

(2013) Fabio Morellini   CELL AND TISSUE RESEARCH

Induction of Hyperhomocysteinemia Models Vascular Dementia by Induction of Cerebral Microhemorrhages and Neuroinflammation

(2013) Tiffany L Sudduth et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

TRPA1 Channels Are Regulators of Astrocyte Basal Calcium Levels and Long-Term Potentiation via Constitutive D-Serine Release

(2013) E. Shigetomi et al.   JOURNAL OF NEUROSCIENCE

An anatomically comprehensive atlas of the adult human brain transcriptome

(2012) Michael J. Hawrylycz et al.   NATURE

NCBI GEO: archive for functional genomics data sets—update

(2012) Tanya Barrett et al.   NUCLEIC ACIDS RESEARCH

The transient receptor potential channel TRPA1: from gene to pathophysiology

(2012) Bernd Nilius et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Allyl isothiocyanates and cinnamaldehyde potentiate miniature excitatory postsynaptic inputs in the supraoptic nucleus in rats

(2011) Toru Yokoyama et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Spatio-temporal transcriptome of the human brain

(2011) Hyo Jung Kang et al.   NATURE

TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3

(2011) Eiji Shigetomi et al.   NATURE NEUROSCIENCE

The cannabinoid WIN 55,212-2-mediated protection of dentate gyrus granule cells is driven by CB1 receptors and modulated by TRPA1 and Cav2.2 channels

(2010) Marco Koch et al.   HIPPOCAMPUS

The AMPA modulator S 18986 improves declarative and working memory performances in aged mice

(2009) Aline Marighetto et al.   BEHAVIOURAL PHARMACOLOGY

Transient receptor potential A1 increase glutamate release on brain stem neurons

(2009) Boram Sun et al.   NEUROREPORT

Long-term Cognitive Impairments in Adult Rats Treated Neonatally with β-N-Methylamino-L-Alanine

(2009) Oskar Karlsson et al.   TOXICOLOGICAL SCIENCES