标题
The transient receptor potential channel TRPA1: from gene to pathophysiology
作者
关键词
-
出版物
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
Volume 464, Issue 5, Pages 425-458
出版商
Springer Nature
发表日期
2012-09-21
DOI
10.1007/s00424-012-1158-z
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- TRPA1 receptors in cough
- (2010) Megan S. Grace et al. PULMONARY PHARMACOLOGY & THERAPEUTICS
- Infrared Snake Eyes: TRPA1 and the Thermal Sensitivity of the Snake Pit Organ
- (2010) V. C. Panzano et al. Science Signaling
- The Role of Transient Receptor Potential Cation Channels in Ca2+ Signaling
- (2010) M. Gees et al. Cold Spring Harbor Perspectives in Biology
- Response to Mechanical Stress Is Mediated by the TRPA Channel Painless in the Drosophila Heart
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- TRPA1 in mast cell activation-induced long-lasting mechanical hypersensitivity of vagal afferent C-fibers in guinea pig esophagus
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- Transient receptor potential ankyrin-1 has a major role in mediating visceral pain in mice
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- Attenuation of Mechanical Hypersensitivity by an Antagonist of the TRPA1 Ion Channel in Diabetic Animals
- (2009) Hong Wei et al. ANESTHESIOLOGY
- TRPA1 activation by lidocaine in nerve terminals results in glutamate release increase
- (2009) Lian-Hua Piao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Essential role for the putative S6 inner pore region in the activation gating of the human TRPA1 channel
- (2009) Jan Benedikt et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Oxime derivatives related to AP18: Agonists and antagonists of the TRPA1 receptor
- (2009) Jeff DeFalco et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Intragastric Administration of TRPV1, TRPV3, TRPM8, and TRPA1 Agonists Modulates Autonomic Thermoregulation in Different Manners in Mice
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- Acute and chronic effects of neurotrophic factors BDNF and GDNF on responses mediated by thermo-sensitive TRP channels in cultured rat dorsal root ganglion neurons
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- Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents
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- Compounds from Sichuan and Melegueta peppers activate, covalently and non-covalently, TRPA1 and TRPV1 channels
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- Endothelium-Dependent Cerebral Artery Dilation Mediated by TRPA1 and Ca 2+ -Activated K + Channels
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- Evidence for Pathogenicity of Atypical Splice Mutations in Autosomal Dominant Polycystic Kidney Disease
- (2009) K. Wang et al. Clinical Journal of the American Society of Nephrology
- TRPA1-mediated responses in trigeminal sensory neurons: interaction between TRPA1 and TRPV1
- (2009) Margaux M. Salas et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Anopheles gambiaeTRPA1 is a heat-activated channel expressed in thermosensitive sensilla of female antennae
- (2009) Guirong Wang et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Transient Receptor Potential A1 and Cannabinoid Receptor Activity in Human Normal and Hyperplastic Prostate: Relation to Nerves and Interstitial Cells
- (2009) Christian Gratzke et al. EUROPEAN UROLOGY
- Functional neurons and melanocytes induced from immortal lines of postnatal neural crest-like stem cells
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- The Ion Channel TRPA1 Is Required for Normal Mechanosensation and Is Modulated by Algesic Stimuli
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- Transient receptor potential A1 mediates gastric distention-induced visceral pain in rats
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- Synthesis and Evaluation of New Alkylamides Derived from α-Hydroxysanshool, the Pungent Molecule in Szechuan Pepper
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- Expression of transient receptor potential ankyrin 1 (TRPA1) in the rat trigeminal sensory afferents and spinal dorsal horn
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- Mechanotransducers in Rat Pulpal Afferents
- (2009) T.O. Hermanstyne et al. JOURNAL OF DENTAL RESEARCH
- Perspectives on TRP Channel Structure and the TRPA1 Puzzle
- (2009) Ramon Latorre JOURNAL OF GENERAL PHYSIOLOGY
- Burning Cold: Involvement of TRPA1 in Noxious Cold Sensation
- (2009) Kelvin Y. Kwan et al. JOURNAL OF GENERAL PHYSIOLOGY
- TRPA1 and Cold Transduction: An Unresolved Issue?
- (2009) Ombretta Caspani et al. JOURNAL OF GENERAL PHYSIOLOGY
- Polymodal Ligand Sensitivity of TRPA1 and Its Modes of Interactions: Figure 1.
- (2009) Sangsu Bang et al. JOURNAL OF GENERAL PHYSIOLOGY
- Non-Neuronal Expression of Transient Receptor Potential Type A1 (TRPA1) in Human Skin
- (2009) Ruzanna Atoyan et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- TRPA1 Modulates Mechanotransduction in Cutaneous Sensory Neurons
- (2009) K. Y. Kwan et al. JOURNAL OF NEUROSCIENCE
- Ozone activates airway nerves via the selective stimulation of TRPA1 ion channels
- (2009) Thomas E. Taylor-Clark et al. JOURNAL OF PHYSIOLOGY-LONDON
- Miogadial and miogatrial with α,β-unsaturated 1,4-dialdehyde moieties—Novel and potent TRPA1 agonists
- (2009) Yusaku Iwasaki et al. LIFE SCIENCES
- High Concentrations of Morphine Sensitize and Activate Mouse Dorsal Root Ganglia via TRPV1 and TRPA1 Receptors
- (2009) Alexander B Forster et al. Molecular Pain
- Pharmacological Blockade of TRPA1 Inhibits Mechanical Firing in Nociceptors
- (2009) Patrick C Kerstein et al. Molecular Pain
- Pore Dilation Occurs in TRPA1 but Not in TRPM8 Channels
- (2009) Jun Chen et al. Molecular Pain
- Nitrooleic Acid, an Endogenous Product of Nitrative Stress, Activates Nociceptive Sensory Nerves via the Direct Activation of TRPA1
- (2009) T. E. Taylor-Clark et al. MOLECULAR PHARMACOLOGY
- Pharmacology of Vanilloid Transient Receptor Potential Cation Channels
- (2009) J. Vriens et al. MOLECULAR PHARMACOLOGY
- Zinc activates damage-sensing TRPA1 ion channels
- (2009) Hongzhen Hu et al. Nature Chemical Biology
- Nicotine activates the chemosensory cation channel TRPA1
- (2009) Karel Talavera et al. NATURE NEUROSCIENCE
- TRPA1 agonists delay gastric emptying in rats through serotonergic pathways
- (2009) Hitoshi Doihara et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Nociceptive Signals Induce Trafficking of TRPA1 to the Plasma Membrane
- (2009) Manuela Schmidt et al. NEURON
- Transient receptor potential A1 increase glutamate release on brain stem neurons
- (2009) Boram Sun et al. NEUROREPORT
- Transient receptor potential channel A1 and noxious cold responses in rat cutaneous nociceptors
- (2009) J.P. Dunham et al. NEUROSCIENCE
- Enhanced activation of the transient receptor potential channel TRPA1 by ajoene, an allicin derivative
- (2009) Ricardo Tsuneo Yassaka et al. NEUROSCIENCE RESEARCH
- Activation of TRPA1 channels by fenamate nonsteroidal anti-inflammatory drugs
- (2009) Hongzhen Hu et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- TRPV1 and TRPA1 Mediate Peripheral Nitric Oxide-Induced Nociception in Mice
- (2009) Takashi Miyamoto et al. PLoS One
- TRPA1 regulates gastrointestinal motility through serotonin release from enterochromaffin cells
- (2009) K. Nozawa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TRPA1 acts as a cold sensor in vitro and in vivo
- (2009) Y. Karashima et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma
- (2009) A. I. Caceres et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TRPA channels distinguish gravity sensing from hearing in Johnston's organ
- (2009) Y. Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Clioquinol and pyrithione activate TRPA1 by increasing intracellular Zn2+
- (2009) D. A. Andersson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TRPA1: A potential target for anti-tussive therapy
- (2009) Thomas E. Taylor-Clark et al. PULMONARY PHARMACOLOGY & THERAPEUTICS
- Cough and gastroesophageal reflux: Insights from animal models
- (2009) Marian Kollarik et al. PULMONARY PHARMACOLOGY & THERAPEUTICS
- Expression of transient receptor potential channel melastin (TRPM) 1–8 and TRPA1 (ankyrin) in mouse inner ear
- (2008) Masaya Takumida et al. ACTA OTO-LARYNGOLOGICA
- Inhibition of transient receptor potential A1 channel by phosphatidylinositol-4,5-bisphosphate
- (2008) Donghee Kim et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- TRPA1 in bradykinin-induced mechanical hypersensitivity of vagal C fibers in guinea pig esophagus
- (2008) Shaoyong Yu et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Transient Receptor Potential Ankyrin 1 Mediates Toluene Diisocyanate–Evoked Respiratory Irritation
- (2008) Thomas E. Taylor-Clark et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Taste-guided identification of high potency TRPA1 agonists from Perilla frutescens
- (2008) Angela Bassoli et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Phospholipase C and protein kinase A mediate bradykinin sensitization of TRPA1: a molecular mechanism of inflammatory pain
- (2008) Shenglan Wang et al. BRAIN
- Overexpression of artemin in the tongue increases expression of TRPV1 and TRPA1 in trigeminal afferents and causes oral sensitivity to capsaicin and mustard oil
- (2008) Christopher M. Elitt et al. BRAIN RESEARCH
- Thymol and related alkyl phenols activate the hTRPA1 channel
- (2008) S P Lee et al. BRITISH JOURNAL OF PHARMACOLOGY
- Curcumin: From ancient medicine to current clinical trials
- (2008) H. Hatcher et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Transient receptor potential channels meet phosphoinositides
- (2008) Bernd Nilius et al. EMBO JOURNAL
- Inflammation reduces mechanical thresholds in a population of transient receptor potential channel A1-expressing nociceptors in the rat
- (2008) James P. Dunham et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Activation of transient receptor potential ankyrin 1 by hydrogen peroxide
- (2008) Yosuke Sawada et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Transient receptor potential A1 mediates an osmotically activated ion channel
- (2008) Xu-Feng Zhang et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Transient receptor potential ankyrin 1 antagonists block the noxious effects of toxic industrial isocyanates and tear gases
- (2008) Bret F. Bessac et al. FASEB JOURNAL
- TRPA1 Mediates the Noxious Effects of Natural Sesquiterpene Deterrents
- (2008) Jasmine Escalera et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Nociceptor Ion Channel TRPA1 Is Potentiated and Inactivated by Permeating Calcium Ions
- (2008) Yuanyuan Y. Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Intracellular alkalization causes pain sensation through activation of TRPA1 in mice
- (2008) Fumitaka Fujita et al. JOURNAL OF CLINICAL INVESTIGATION
- TRPA1 is a major oxidant sensor in murine airway sensory neurons
- (2008) Bret F. Bessac et al. JOURNAL OF CLINICAL INVESTIGATION
- TRPA1 Channels Mediate Cold Temperature Sensing in Mammalian Vagal Sensory Neurons: Pharmacological and Genetic Evidence
- (2008) O. Fajardo et al. JOURNAL OF NEUROSCIENCE
- Identification of Transmembrane Domain 5 as a Critical Molecular Determinant of Menthol Sensitivity in Mammalian TRPA1 Channels
- (2008) B. Xiao et al. JOURNAL OF NEUROSCIENCE
- Transient Receptor Potential A1 Is a Sensory Receptor for Multiple Products of Oxidative Stress
- (2008) D. A. Andersson et al. JOURNAL OF NEUROSCIENCE
- Molecular Determinants of Species-Specific Activation or Blockade of TRPA1 Channels
- (2008) J. Chen et al. JOURNAL OF NEUROSCIENCE
- Zebrafish TRPA1 Channels Are Required for Chemosensation But Not for Thermosensation or Mechanosensory Hair Cell Function
- (2008) D. A. Prober et al. JOURNAL OF NEUROSCIENCE
- Plant-Derived Cannabinoids Modulate the Activity of Transient Receptor Potential Channels of Ankyrin Type-1 and Melastatin Type-8
- (2008) L. De Petrocellis et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Expression and function of the ion channel TRPA1 in vagal afferent nerves innervating mouse lungs
- (2008) Christina Nassenstein et al. JOURNAL OF PHYSIOLOGY-LONDON
- Relative contributions of TRPA1 and TRPV1 channels in the activation of vagal bronchopulmonary C-fibres by the endogenous autacoid 4-oxononenal
- (2008) T. E. Taylor-Clark et al. JOURNAL OF PHYSIOLOGY-LONDON
- Cutaneous Nociception Evoked by 15-delta PGJ2 via Activation of Ion Channel TRPA1
- (2008) Lillian Cruz-Orengo et al. Molecular Pain
- Activation of TRPA1 by Farnesyl Thiosalicylic Acid
- (2008) M. Maher et al. MOLECULAR PHARMACOLOGY
- An internal thermal sensor controlling temperature preference in Drosophila
- (2008) Fumika N. Hamada et al. NATURE
- Drosophila TRPA channel modulates sugar-stimulated neural excitation, avoidance and social response
- (2008) Jie Xu et al. NATURE NEUROSCIENCE
- Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels
- (2008) Diana M Bautista et al. NATURE NEUROSCIENCE
- Control of thermotactic behavior via coupling of a TRP channel to a phospholipase C signaling cascade
- (2008) Young Kwon et al. NATURE NEUROSCIENCE
- Activation of transient receptor potential A1 channels by mustard oil, tetrahydrocannabinol and Ca2+ reveals different functional channel states
- (2008) E.J. Cavanaugh et al. NEUROSCIENCE
- Transient receptor potential ankyrin-1 participates in visceral hyperalgesia following experimental colitis
- (2008) Jing Yang et al. NEUROSCIENCE LETTERS
- Modulation of the transient receptor potential channel TRPA1 by phosphatidylinositol 4,5-biphosphate manipulators
- (2008) Yuji Karashima et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Breathtaking TRP Channels: TRPA1 and TRPV1 in Airway Chemosensation and Reflex Control
- (2008) Bret F. Bessac et al. PHYSIOLOGY
- Cox-dependent fatty acid metabolites cause pain through activation of the irritant receptor TRPA1
- (2008) S. Materazzi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Caffeine activates mouse TRPA1 channels but suppresses human TRPA1 channels
- (2008) K. Nagatomo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- General anesthetics activate a nociceptive ion channel to enhance pain and inflammation
- (2008) J. A. Matta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Differential Expression Profile of Cold (TRPA1) and Cool (TRPM8) Receptors in Human Urogenital Organs
- (2008) Shuqi Du et al. UROLOGY
- Δ9-Tetrahydrocannabinol inhibits electrically-evoked CGRP release and capsaicin-sensitive sensory neurogenic vasodilatation in the rat mesenteric arterial bed
- (2007) J D Wilkinson et al. BRITISH JOURNAL OF PHARMACOLOGY
- Icilin induces a hyperthermia in rats that is dependent on nitric oxide production and NMDA receptor activation
- (2007) Zhe Ding et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Editorial Comment on: Distribution and Function of the Hydrogen Sulfide–Sensitive TRPA1 Ion Channel in Rat Urinary Bladder
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- Distribution and Function of the Hydrogen Sulfide–Sensitive TRPA1 Ion Channel in Rat Urinary Bladder
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