标题
Effects of antiepileptic drugs in a new TSC/mTOR-dependent epilepsy mouse model
作者
关键词
-
出版物
Annals of Clinical and Translational Neurology
Volume 6, Issue 7, Pages 1273-1291
出版商
Wiley
发表日期
2019-06-26
DOI
10.1002/acn3.50829
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mechanistic target of rapamycin complex 1 and 2 in human temporal lobe epilepsy
- (2018) Delia M. Talos et al. ANNALS OF NEUROLOGY
- mTOR dysregulation and tuberous sclerosis-related epilepsy
- (2018) Paolo Curatolo et al. Expert Review of Neurotherapeutics
- Second-hit mosaic mutation in mTORC1 repressor DEPDC5 causes focal cortical dysplasia–associated epilepsy
- (2018) Théo Ribierre et al. JOURNAL OF CLINICAL INVESTIGATION
- Corticostriatal Transmission Is Selectively Enhanced in Striatonigral Neurons with Postnatal Loss of Tsc1
- (2018) Katelyn N. Benthall et al. Cell Reports
- mTOR dysregulation and tuberous sclerosis-related epilepsy
- (2018) Paolo Curatolo et al. Expert Review of Neurotherapeutics
- The novel, catalytic mTORC1/2 inhibitor PQR620 and the PI3K/mTORC1/2 inhibitor PQR530 effectively cross the blood-brain barrier and increase seizure threshold in a mouse model of chronic epilepsy
- (2018) Claudia Brandt et al. NEUROPHARMACOLOGY
- PI3K–mTOR Pathway Inhibition Exhibits Efficacy Against High-grade Glioma in Clinically Relevant Mouse Models
- (2016) Fan Lin et al. CLINICAL CANCER RESEARCH
- Causes of mortality in individuals with tuberous sclerosis complex
- (2016) Sam Amin et al. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
- Interdependence of clinical factors predicting cognition in children with tuberous sclerosis complex
- (2016) I. E. Overwater et al. JOURNAL OF NEUROLOGY
- Sudden unexpected death in epilepsy: epidemiology, mechanisms, and prevention
- (2016) Orrin Devinsky et al. LANCET NEUROLOGY
- Valproic acid after five decades of use in epilepsy: time to reconsider the indications of a time-honoured drug
- (2016) Torbjörn Tomson et al. LANCET NEUROLOGY
- Sirolimus for epilepsy in children with tuberous sclerosis complex
- (2016) Iris E. Overwater et al. NEUROLOGY
- Presynaptic Protein Synthesis Is Required for Long-Term Plasticity of GABA Release
- (2016) Thomas J. Younts et al. NEURON
- mTOR pathway inhibition as a new therapeutic strategy in epilepsy and epileptogenesis
- (2016) Rita Citraro et al. PHARMACOLOGICAL RESEARCH
- The role of antiepileptic drugs in sudden unexpected death in epilepsy
- (2016) Dag Aurlien et al. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
- Fine Mapping of a Dravet Syndrome Modifier Locus on Mouse Chromosome 5 and Candidate Gene Analysis by RNA-Seq
- (2016) Nicole A. Hawkins et al. PLoS Genetics
- Intermittent dosing of rapamycin maintains antiepileptogenic effects in a mouse model of tuberous sclerosis complex
- (2015) Nicholas Rensing et al. EPILEPSIA
- Epilepsy in children with tuberous sclerosis complex: Chance of remission and response to antiepileptic drugs
- (2015) Iris E. Overwater et al. EPILEPSIA
- Intact neuronal function in Rheb1 mutant mice: implications for TORC1-based treatments
- (2015) S. M. I. Goorden et al. HUMAN MOLECULAR GENETICS
- HCN channels are a novel therapeutic target for cognitive dysfunction in Neurofibromatosis type 1
- (2015) A Omrani et al. MOLECULAR PSYCHIATRY
- Spreading depolarization in the brainstem mediates sudden cardiorespiratory arrest in mouse SUDEP models
- (2015) Isamu Aiba et al. Science Translational Medicine
- Adenosine Triphosphate-Competitive mTOR Inhibitors: A New Class of Immunosuppressive Agents That Inhibit Allograft Rejection
- (2014) B. R. Rosborough et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Clobazam and Its Active Metabolite N-desmethylclobazam Display Significantly Greater Affinities for α2- versus α1-GABAA–Receptor Complexes
- (2014) Henrik Sindal Jensen et al. PLoS One
- FMRP S499 Is Phosphorylated Independent of mTORC1-S6K1 Activity
- (2014) Christopher M. Bartley et al. PLoS One
- TORC1-dependent epilepsy caused by acute biallelicTsc1deletion in adult mice
- (2013) Elisabeth Abs et al. ANNALS OF NEUROLOGY
- Excitatory/Inhibitory Synaptic Imbalance Leads to Hippocampal Hyperexcitability in Mouse Models of Tuberous Sclerosis
- (2013) Helen S. Bateup et al. NEURON
- Vigabatrin Inhibits Seizures and mTOR Pathway Activation in a Mouse Model of Tuberous Sclerosis Complex
- (2013) Bo Zhang et al. PLoS One
- Structural basis of AMPK regulation by small molecule activators
- (2013) Bing Xiao et al. Nature Communications
- Sudden Unexpected Death in Epilepsy
- (2012) Dale C. Hesdorffer et al. CNS DRUGS
- mTOR Inhibitors in Tuberous Sclerosis Complex
- (2012) Paolo Curatolo et al. Current Neuropharmacology
- Understanding relationships between autism, intelligence, and epilepsy: a cross-disorder approach
- (2012) AGNIES M van EEGHEN et al. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
- Management of epilepsy associated with tuberous sclerosis complex (TSC): Clinical recommendations
- (2012) Paolo Curatolo et al. EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
- Time-Dependent Modulation of Mitogen Activated Protein Kinases and AKT in Rat Hippocampus and Cortex in the Pilocarpine Model of Epilepsy
- (2012) Mark William Lopes et al. NEUROCHEMICAL RESEARCH
- Sustained Activation of mTOR Pathway in Embryonic Neural Stem Cells Leads to Development of Tuberous Sclerosis Complex-Associated Lesions
- (2011) Laura Magri et al. Cell Stem Cell
- Long-term neurological outcome in children with early-onset epilepsy associated with tuberous sclerosis
- (2011) Raffaella Cusmai et al. EPILEPSY & BEHAVIOR
- Low glycemic index treatment for epilepsy in tuberous sclerosis complex
- (2011) Anna M. Larson et al. EPILEPSY RESEARCH
- Antiepileptic treatment before the onset of seizures reduces epilepsy severity and risk of mental retardation in infants with tuberous sclerosis complex
- (2011) Sergiusz Jóźwiak et al. EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
- Therapeutic role of mammalian target of rapamycin (mTOR) inhibition in preventing epileptogenesis
- (2011) Sharon S. McDaniel et al. NEUROSCIENCE LETTERS
- Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex
- (2011) J. Goto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1)
- (2010) Laura R. Pearce et al. BIOCHEMICAL JOURNAL
- Interactions of stiripentol with clobazam and valproate in the mouse maximal electroshock-induced seizure model
- (2010) Jarogniew J. Luszczki et al. EPILEPSY RESEARCH
- Targeted treatments for cognitive and neurodevelopmental disorders in tuberous sclerosis complex
- (2010) Petrus J. Vries Neurotherapeutics
- The tuberous sclerosis complex
- (2009) Ksenia A. Orlova et al. Annals of the New York Academy of Sciences
- AZD8055 Is a Potent, Selective, and Orally Bioavailable ATP-Competitive Mammalian Target of Rapamycin Kinase Inhibitor with In vitro and In vivo Antitumor Activity
- (2009) C. M. Chresta et al. CANCER RESEARCH
- The natural history of epilepsy in tuberous sclerosis complex
- (2009) Catherine J. Chu-Shore et al. EPILEPSIA
- Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex
- (2008) Ling-Hui Zeng et al. ANNALS OF NEUROLOGY
- Tuberous sclerosis
- (2008) Paolo Curatolo et al. LANCET
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