Interferon-Inducible Protein 16 (IFI16) Has a Broad-Spectrum Binding Ability Against ssDNA Targets: An Evolutionary Hypothesis for Antiretroviral Checkpoint

Roles of Endogenous Retroviruses in Early Life Events

(2017) Gkikas Magiorkinis et al.   TRENDS IN MICROBIOLOGY

Epigenetic Control of Human Endogenous Retrovirus Expression: Focus on Regulation of Long-Terminal Repeats (LTRs)

(2017) Tara Hurst et al.   Viruses-Basel

IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP

(2017) K. L. Jønsson et al.   Nature Communications

Protect this house: cytosolic sensing of viruses

(2017) Michael J McFadden et al.   Current Opinion in Virology

A human endogenous retrovirus-derived gene that can contribute to oncogenesis by activating the ERK pathway and inducing migration and invasion

(2017) Cécile Lemaître et al.   PLoS Pathogens

Viral evasion of intracellular DNA and RNA sensing

(2016) Ying Kai Chan et al.   NATURE REVIEWS MICROBIOLOGY

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

(2016) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Discovery of unfixed endogenous retrovirus insertions in diverse human populations

(2016) Julia Halo Wildschutte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endogenous retroviral promoter exaptation in human cancer

(2016) Artem Babaian et al.   Mobile DNA

IFI16 Preferentially Binds to DNA with Quadruplex Structure and Enhances DNA Quadruplex Formation

(2016) Lucia Hároníková et al.   PLoS One

Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses

(2015) Katherine B. Chiappinelli et al.   CELL

Intracellular detection of viral nucleic acids

(2015) Konstantin MJ Sparrer et al.   CURRENT OPINION IN MICROBIOLOGY

Activation of the innate immune response by endogenous retroviruses

(2015) Tara P. Hurst et al.   JOURNAL OF GENERAL VIROLOGY

Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA

(2015) Anna-Maria Herzner et al.   NATURE IMMUNOLOGY

The decline of human endogenous retroviruses: extinction and survival

(2015) Gkikas Magiorkinis et al.   Retrovirology

Innate immune recognition of DNA: A recent history

(2015) Alan Dempsey et al.   VIROLOGY

Differential Expression of HERV-K (HML-2) Proviruses in Cells and Virions of the Teratocarcinoma Cell Line Tera-1

(2015) Neeru Bhardwaj et al.   Viruses-Basel

IFI16Expression Is Related to Selected Transcription Factors during B-Cell Differentiation

(2015) Pier Paolo Piccaluga et al.   Journal of Immunology Research

IFI16: At the interphase between innate DNA sensing and genome regulation

(2014) Martin R. Jakobsen et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Listeria monocytogenes induces IFN  expression through an IFI16-, cGAS- and STING-dependent pathway

(2014) K. Hansen et al.   EMBO JOURNAL

Unfixed Endogenous Retroviral Insertions in the Human Population

(2014) E. Marchi et al.   JOURNAL OF VIROLOGY

Larger Mammalian Body Size Leads to Lower Retroviral Activity

(2014) Aris Katzourakis et al.   PLoS Pathogens

An Infection-Relevant Transcriptomic Compendium for Salmonella enterica Serovar Typhimurium

(2013) Carsten Kröger et al.   Cell Host & Microbe

Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING

(2013) Xu Zhang et al.   MOLECULAR CELL

Human-specific endogenous retroviral insert serves as an enhancer for the schizophrenia-linked gene PRODH

(2013) M. Suntsova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PNAS Plus: From the Cover: IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication

(2013) M. R. Jakobsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IFI16 DNA Sensor Is Required for Death of Lymphoid CD4 T Cells Abortively Infected with HIV

(2013) K. M. Monroe et al.   SCIENCE

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Preferential binding of IFI16 protein to cruciform structure and superhelical DNA

(2012) Václav Brázda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

(2012) Tengchuan Jin et al.   IMMUNITY

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Microarray-Based Sketches of the HERV Transcriptome Landscape

(2012) Philippe Pérot et al.   PLoS One

HERV-H RNA is abundant in human embryonic stem cells and a precise marker for pluripotency

(2012) Federico A Santoni et al.   Retrovirology

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

(2012) L. Sun et al.   SCIENCE

The proapoptotic activity of the Interferon-inducible gene IFI16 provides new insights into its etiopathogenetic role in autoimmunity

(2010) Francesca Gugliesi et al.   JOURNAL OF AUTOIMMUNITY

Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity

(2008) Daniel B. Stetson et al.   CELL

The TREX1 Double-stranded DNA Degradation Activity Is Defective in Dominant Mutations Associated with Autoimmune Disease

(2008) Duane A. Lehtinen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of IFI16 in DNA damage and checkpoint

(2007) Mutsuko Ouchi   Frontiers in Bioscience-Landmark