IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP
出版年份 2017 全文链接
标题
IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP
作者
关键词
-
出版物
Nature Communications
Volume 8, Issue -, Pages 14391
出版商
Springer Nature
发表日期
2017-02-10
DOI
10.1038/ncomms14391
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The AIM2-like Receptors Are Dispensable for the Interferon Response to Intracellular DNA
- (2016) Elizabeth E. Gray et al. IMMUNITY
- Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses
- (2016) Christian K. Holm et al. Nature Communications
- PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1
- (2015) Sunnie M. Yoh et al. CELL
- STING Activation by Translocation from the ER Is Associated with Infection and Autoinflammatory Disease
- (2015) Nicole Dobbs et al. Cell Host & Microbe
- cGAS and Ifi204 Cooperate To Produce Type I IFNs in Response toFrancisellaInfection
- (2015) Kelly M. Storek et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi–Goutières Syndrome
- (2015) Elizabeth E. Gray et al. JOURNAL OF IMMUNOLOGY
- Activation and Regulation of DNA-Driven Immune Responses
- (2015) Søren R. Paludan MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA
- (2015) B. A. Diner et al. Molecular Systems Biology
- Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA
- (2015) Anna-Maria Herzner et al. NATURE IMMUNOLOGY
- Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases
- (2015) Daxing Gao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection
- (2015) Megan H. Orzalli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation
- (2015) S. Liu et al. SCIENCE
- NF-κB activation induced by hepatitis A virus and Newcastle disease virus occurs by different pathways depending on the structural pattern of viral nucleic acids
- (2014) Dajana Paulmann et al. ARCHIVES OF VIROLOGY
- The mechanism of double-stranded DNA sensing through the cGAS-STING pathway
- (2014) Chang Shu et al. CYTOKINE & GROWTH FACTOR REVIEWS
- IFI16: At the interphase between innate DNA sensing and genome regulation
- (2014) Martin R. Jakobsen et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Listeria monocytogenes induces IFN expression through an IFI16-, cGAS- and STING-dependent pathway
- (2014) K. Hansen et al. EMBO JOURNAL
- The E3 Ubiquitin Ligase AMFR and INSIG1 Bridge the Activation of TBK1 Kinase by Modifying the Adaptor STING
- (2014) Qiang Wang et al. IMMUNITY
- Interferon γ-inducible Protein (IFI) 16 Transcriptionally Regulates Type I Interferons and Other Interferon-stimulated Genes and Controls the Interferon Response to both DNA and RNA Viruses
- (2014) Mikayla R. Thompson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The ribonuclease activity of SAMHD1 is required for HIV-1 restriction
- (2014) Jeongmin Ryoo et al. NATURE MEDICINE
- A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation
- (2014) Michael L. van de Weijer et al. Nature Communications
- The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop
- (2014) Xu Zhang et al. Cell Reports
- Cyclic Dinucleotides Trigger ULK1 (ATG1) Phosphorylation of STING to Prevent Sustained Innate Immune Signaling
- (2013) Hiroyasu Konno et al. CELL
- Human Cytomegalovirus Tegument Protein pUL83 Inhibits IFI16-Mediated DNA Sensing for Immune Evasion
- (2013) Tuo Li et al. Cell Host & Microbe
- Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization
- (2013) Xin Li et al. IMMUNITY
- The Capsids of HIV-1 and HIV-2 Determine Immune Detection of the Viral cDNA by the Innate Sensor cGAS in Dendritic Cells
- (2013) Xavier Lahaye et al. IMMUNITY
- The interferon response to intracellular DNA: Why so many receptors?
- (2013) Leonie Unterholzner IMMUNOBIOLOGY
- Proteasomal Degradation of Herpes Simplex Virus Capsids in Macrophages Releases DNA to the Cytosol for Recognition by DNA Sensors
- (2013) K. A. Horan et al. JOURNAL OF IMMUNOLOGY
- STING Recognition of Cytoplasmic DNA Instigates Cellular Defense
- (2013) Takayuki Abe et al. MOLECULAR CELL
- cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
- (2013) Andrea Ablasser et al. NATURE
- Structural mechanism of cytosolic DNA sensing by cGAS
- (2013) Filiz Civril et al. NATURE
- Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP
- (2013) Andrea Ablasser et al. NATURE
- Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity
- (2013) John W. Schoggins et al. NATURE
- Single Nucleotide Polymorphisms of Human STING Can Affect Innate Immune Response to Cyclic Dinucleotides
- (2013) Guanghui Yi et al. PLoS One
- PNAS Plus: From the Cover: IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication
- (2013) M. R. Jakobsen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cooperative assembly of IFI16 filaments on dsDNA provides insights into host defense strategy
- (2013) S. R. Morrone et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pivotal Roles of cGAS-cGAMP Signaling in Antiviral Defense and Immune Adjuvant Effects
- (2013) X.-D. Li et al. SCIENCE
- Cyclic GMP-AMP Synthase Is an Innate Immune Sensor of HIV and Other Retroviruses
- (2013) D. Gao et al. SCIENCE
- STING-Dependent Recognition of Cyclic di-AMP Mediates Type I Interferon Responses during Chlamydia trachomatis Infection
- (2013) J. R. Barker et al. mBio
- Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity
- (2013) Philip J. Kranzusch et al. Cell Reports
- The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING
- (2013) Elie J. Diner et al. Cell Reports
- Preferential binding of IFI16 protein to cruciform structure and superhelical DNA
- (2012) Václav Brázda et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor
- (2012) Tengchuan Jin et al. IMMUNITY
- Extensive evolutionary and functional diversity among mammalian AIM2-like receptors
- (2012) Rebecca L. Brunette et al. JOURNAL OF EXPERIMENTAL MEDICINE
- SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates
- (2012) Hichem Lahouassa et al. NATURE IMMUNOLOGY
- Development of Transgenic Cloned Pig Models of Skin Inflammation by DNA Transposon-Directed Ectopic Expression of Human β1 and α2 Integrin
- (2012) Nicklas Heine Staunstrup et al. PLoS One
- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
- (2012) L. Sun et al. SCIENCE
- STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway
- (2012) Y. Tanaka et al. Science Signaling
- IFI16 Acts as a Nuclear Pathogen Sensor to Induce the Inflammasome in Response to Kaposi Sarcoma-Associated Herpesvirus Infection
- (2011) Nagaraj Kerur et al. Cell Host & Microbe
- IFI16 is an innate immune sensor for intracellular DNA
- (2010) Leonie Unterholzner et al. NATURE IMMUNOLOGY
- Amelioration of Psoriasis by Anti-TNF-α RNAi in the Xenograft Transplantation Model
- (2009) Maria Jakobsen et al. MOLECULAR THERAPY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More