Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking

DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors

(2019) Christopher S. McGinnis et al.   Cell Systems

Mechanosensing at integrin-mediated cell–matrix adhesions: from molecular to integrated mechanisms

(2018) Nils C Gauthier et al.   CURRENT OPINION IN CELL BIOLOGY

TRPM7 regulates angiotensin II-induced sinoatrial node fibrosis in sick sinus syndrome rats by mediating Smad signaling

(2018) Hongbin Zhong et al.   HEART AND VESSELS

Telocytes in the human sinoatrial node

(2017) Lubov B. Mitrofanova et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mechanotransduction at the cell-matrix interface

(2017) K.A. Jansen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Region and cell-type resolved quantitative proteomic map of the human heart

(2017) Sophia Doll et al.   Nature Communications

An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes

(2017) Dorte B. Bekker-Jensen et al.   Cell Systems

On the Dependency of Cellular Protein Levels on mRNA Abundance

(2016) Yansheng Liu et al.   CELL

Mechanosensing via cell-matrix adhesions in 3D microenvironments

(2016) Andrew D. Doyle et al.   EXPERIMENTAL CELL RESEARCH

Ca2+/calmodulin-activated phosphodiesterase 1A is highly expressed in rabbit cardiac sinoatrial nodal cells and regulates pacemaker function

(2016) Yevgeniya O. Lukyanenko et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Voltage-gated calcium channels and their auxiliary subunits: physiology and pathophysiology and pharmacology

(2016) Annette C. Dolphin   JOURNAL OF PHYSIOLOGY-LONDON

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

The MaxQuant computational platform for mass spectrometry-based shotgun proteomics

(2016) Stefka Tyanova et al.   Nature Protocols

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

(2016) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

RNA Sequencing of Mouse Sinoatrial Node Reveals an Upstream Regulatory Role for Islet-1 in Cardiac Pacemaker Cells

(2015) V. Vedantham et al.   CIRCULATION RESEARCH

Expanding Roles for Lipid Droplets

(2015) Michael A. Welte   CURRENT BIOLOGY

2016 update of the PRIDE database and its related tools

(2015) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

Functional role of voltage gated Ca2+ channels in heart automaticity

(2015) Pietro Mesirca et al.   Frontiers in Physiology

Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis

(2014) Bo Liang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

New and notable ion-channels in the sarcoplasmic/endoplasmic reticulum: do they support the process of intracellular Ca2+release?

(2014) Hiroshi Takeshima et al.   JOURNAL OF PHYSIOLOGY-LONDON

Rapid and Deep Proteomes by Faster Sequencing on a Benchtop Quadrupole Ultra-High-Field Orbitrap Mass Spectrometer

(2014) Christian D. Kelstrup et al.   JOURNAL OF PROTEOME RESEARCH

Defining the Human Adipose Tissue Proteome To Reveal Metabolic Alterations in Obesity

(2014) Adil Mardinoglu et al.   JOURNAL OF PROTEOME RESEARCH

Off-Line High-pH Reversed-Phase Fractionation for In-Depth Phosphoproteomics

(2014) Tanveer S. Batth et al.   JOURNAL OF PROTEOME RESEARCH

Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ

(2014) Jürgen Cox et al.   MOLECULAR & CELLULAR PROTEOMICS

Uncoupling Protein-1 and Related Messenger Ribonucleic Acids in Human Epicardial and Other Adipose Tissues: Epicardial Fat Functioning as Brown Fat

(2014) Harold S. Sacks et al.   MOLECULAR ENDOCRINOLOGY

Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics

(2014) Alicia Lundby et al.   NATURE METHODS

Importance of Gradients in Membrane Properties and Electrical Coupling in Sinoatrial Node Pacing

(2014) Shin Inada et al.   PLoS One

Integration of Cardiac Proteome Biology and Medicine by a Specialized Knowledgebase

(2013) Nobel C. Zong et al.   CIRCULATION RESEARCH

Anatomical Locations of Human Brown Adipose Tissue: Functional Relevance and Implications in Obesity and Type 2 Diabetes

(2013) H. Sacks et al.   DIABETES

The regulatory roles of small leucine-rich proteoglycans in extracellular matrix assembly

(2013) Shoujun Chen et al.   FEBS Journal

Recessive and dominant mutations in COL12A1 cause a novel EDS/myopathy overlap syndrome in humans and mice

(2013) Yaqun Zou et al.   HUMAN MOLECULAR GENETICS

Mutations in the collagen XII gene define a new form of extracellular matrix-related myopathy

(2013) D. Hicks et al.   HUMAN MOLECULAR GENETICS

Using transmission electron microscopy and 3View to determine collagen fibril size and three-dimensional organization

(2013) Tobias Starborg et al.   Nature Protocols

Structure, function and clinical relevance of the cardiac conduction system, including the atrioventricular ring and outflow tract tissues

(2013) Halina Dobrzynski et al.   PHARMACOLOGY & THERAPEUTICS

Metabolic Syndrome Remodels Electrical Activity of the Sinoatrial Node and Produces Arrhythmias in Rats

(2013) Alondra Albarado-Ibañez et al.   PLoS One

Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity

(2013) R. Sah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vivo Phosphoproteomics Analysis Reveals the Cardiac Targets of  -Adrenergic Receptor Signaling

(2013) A. Lundby et al.   Science Signaling

Decorin

(2012) Thomas Neill et al.   AMERICAN JOURNAL OF PATHOLOGY

Kinesin motors and primary cilia

(2012) Kristen J. Verhey et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

clusterMaker: a multi-algorithm clustering plugin for Cytoscape

(2012) John H Morris et al.   BMC BIOINFORMATICS

Lipid Metabolism and Toxicity in the Heart

(2012) Ira J. Goldberg et al.   Cell Metabolism

Proteomic Analysis of Mammalian Primary Cilia

(2012) Hiroaki Ishikawa et al.   CURRENT BIOLOGY

Differential and restricted expression of novel collagen VI chains in mouse

(2011) Sudheer Kumar Gara et al.   MATRIX BIOLOGY

Extracellular Matrix Composition and Remodeling in Human Abdominal Aortic Aneurysms: A Proteomics Approach

(2011) Athanasios Didangelos et al.   MOLECULAR & CELLULAR PROTEOMICS

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Collagen XV Is Necessary for Modeling of the Extracellular Matrix and Its Deficiency Predisposes to Cardiomyopathy

(2010) Karolina Rasi et al.   CIRCULATION RESEARCH

A Coupled SYSTEM of Intracellular Ca 2+ Clocks and Surface Membrane Voltage Clocks Controls the Timekeeping Mechanism of the Heart’s Pacemaker

(2010) Edward G. Lakatta et al.   CIRCULATION RESEARCH

The role of small leucine-rich proteoglycans in collagen fibrillogenesis

(2010) Sebastian Kalamajski et al.   MATRIX BIOLOGY

Molecular Architecture of the Human Sinus Node

(2009) Natalie J. Chandler et al.   CIRCULATION

What keeps us ticking: a funny current, a calcium clock, or both?

(2009) Edward G. Lakatta et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

P2 purinergic receptor mRNA in rat and human sinoatrial node and other heart regions

(2009) Hanny Musa et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY