Sevoflurane induces cognitive impairment in young mice via autophagy

Attenuating oxygen-glucose deprivation-caused autophagosome accumulation may be involved in sevoflurane postconditioning-induced protection in human neuron-like cells

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Excessive apoptosis and disordered autophagy flux contribute to the neurotoxicity induced by high iodine in Sprague-Dawley rat

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PBDE-209 exposure damages learning and memory ability in rats potentially through increased autophagy and apoptosis in the hippocampus neuron

(2017) Wen Sun et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Effect of Anesthesia on the Developing Brain: Infant and Fetus

(2017) Dean B. Andropoulos   FETAL DIAGNOSIS AND THERAPY

Sevoflurane neurotoxicity in neonatal rats is related to an increase in the GABAA R α1/GABAA R α2 ratio

(2017) Si-Ning Xie et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Anesthetic neurotoxicity: Apoptosis and autophagic cell death mediated by calcium dysregulation

(2017) Meirong Yang et al.   NEUROTOXICOLOGY AND TERATOLOGY

Autophagy and Its Impact on Neurodegenerative Diseases: New Roles for TDP-43 and C9orf72

(2017) Mauricio Budini et al.   Frontiers in Molecular Neuroscience

Autophagy down regulates pro-inflammatory mediators in BV2 microglial cells and rescues both LPS and alpha-synuclein induced neuronal cell death

(2017) Claudio Bussi et al.   Scientific Reports

General Anesthetics Regulate Autophagy via Modulating the Inositol 1,4,5-Trisphosphate Receptor: Implications for Dual Effects of Cytoprotection and Cytotoxicity

(2017) Gongyi Ren et al.   Scientific Reports

Mammalian Autophagy: How Does It Work?

(2016) Carla F. Bento et al.   Annual Review of Biochemistry

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(2016) Daniel J Klionsky et al.   Autophagy

Lasting impact of general anaesthesia on the brain: mechanisms and relevance

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Sevoflurane-Induced Endoplasmic Reticulum Stress Contributes to Neuroapoptosis and BACE-1 Expression in the Developing Brain: The Role of eIF2α

(2016) Bin Liu et al.   NEUROTOXICITY RESEARCH

Autophagy Is Involved in the Sevoflurane Anesthesia-Induced Cognitive Dysfunction of Aged Rats

(2016) Xiaoming Zhang et al.   PLoS One

Long-term Effects of Single or Multiple Neonatal Sevoflurane Exposures on Rat Hippocampal Ultrastructure

(2015) Levana G. Amrock et al.   ANESTHESIOLOGY

Identifying an essential role of nuclear LC3 for autophagy

(2015) Rui Huang et al.   Autophagy

p62/SQSTM1 functions as a signaling hub and an autophagy adaptor

(2015) Yoshinori Katsuragi et al.   FEBS Journal

Radiocontrast-induced nephropathy is attenuated by autophagy through regulation of apoptosis and inflammation

(2015) Gang Jee Ko et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

The functional and pathologic relevance of autophagy proteases

(2015) Álvaro F. Fernández et al.   JOURNAL OF CLINICAL INVESTIGATION

Pre-administration of curcumin prevents neonatal sevoflurane exposure-induced neurobehavioral abnormalities in mice

(2015) Mu-Huo Ji et al.   NEUROTOXICOLOGY

Acute and Long-Term Effects of Brief Sevoflurane Anesthesia During the Early Postnatal Period in Rats

(2015) Lin Qiu et al.   TOXICOLOGICAL SCIENCES

Sevoflurane Induces Tau Phosphorylation and Glycogen Synthase Kinase 3β Activation in Young Mice

(2014) Guorong Tao et al.   ANESTHESIOLOGY

Autophagy and Its Normal and Pathogenic States in the Brain

(2014) Ai Yamamoto et al.   Annual Review of Neuroscience

Both JNK and P38 MAPK pathways participate in the protection by dexmedetomidine against isoflurane-induced neuroapoptosis in the hippocampus of neonatal rats

(2014) Zhaoxia Liao et al.   BRAIN RESEARCH BULLETIN

The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration

(2014) David Heras-Sandoval et al.   CELLULAR SIGNALLING

Anesthetic Sevoflurane Reduces Levels of Hippocalcin and Postsynaptic Density Protein 95

(2014) Jie Zhang et al.   MOLECULAR NEUROBIOLOGY

Erythropoietin protects newborn rat against sevoflurane-induced neurotoxicity

(2014) Lionel Pellegrini et al.   PEDIATRIC ANESTHESIA

The Effect of Endoplasmic Reticulum Stress on Neurotoxicity Caused by Inhaled Anesthetics

(2013) Mari Komita et al.   ANESTHESIA AND ANALGESIA

Selective Anesthesia-induced Neuroinflammation in Developing Mouse Brain and Cognitive Impairment

(2013) Xia Shen et al.   ANESTHESIOLOGY

Isoflurane-induced Apoptosis of Neurons and Oligodendrocytes in the Fetal Rhesus Macaque Brain

(2013) Catherine E. Creeley et al.   ANESTHESIOLOGY

Distinct long-term neurocognitive outcomes after equipotent sevoflurane or isoflurane anaesthesia in immature rats

(2013) T.M. Ramage et al.   BRITISH JOURNAL OF ANAESTHESIA

The role of cell signalling in the crosstalk between autophagy and apoptosis

(2013) Laurence A. Booth et al.   CELLULAR SIGNALLING

Sevoflurane Induces Endoplasmic Reticulum Stress Mediated Apoptosis in Hippocampal Neurons of Aging Rats

(2013) Gang Chen et al.   PLoS One

Anesthetics isoflurane and desflurane differently affect mitochondrial function, learning, and memory

(2012) Yiying Zhang et al.   ANNALS OF NEUROLOGY

Comparison of the Neuroapoptotic Properties of Equipotent Anesthetic Concentrations of Desflurane, Isoflurane, or Sevoflurane in Neonatal Mice

(2011) George K. Istaphanous et al.   ANESTHESIOLOGY

Isoflurane Causes Greater Neurodegeneration Than an Equivalent Exposure of Sevoflurane in the Developing Brain of Neonatal Mice

(2010) Ge Liang et al.   ANESTHESIOLOGY

Anesthetic Sevoflurane Causes Neurotoxicity Differently in Neonatal Naïve and Alzheimer Disease Transgenic Mice

(2010) Yan Lu et al.   ANESTHESIOLOGY

Autophagosome Formation and Molecular Mechanism of Autophagy

(2010) Isei Tanida   ANTIOXIDANTS & REDOX SIGNALING

Different apoptosis ratios and gene expressions in two human cell lines after sevoflurane anaesthesia

(2009) S. KVOLIK et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells

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Brain and behavior changes in 12-month-old Tg2576 and nontransgenic mice exposed to anesthetics

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