Autophagy and Its Impact on Neurodegenerative Diseases: New Roles for TDP-43 and C9orf72
出版年份 2017 全文链接
标题
Autophagy and Its Impact on Neurodegenerative Diseases: New Roles for TDP-43 and C9orf72
作者
关键词
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出版物
Frontiers in Molecular Neuroscience
Volume 10, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2017-05-30
DOI
10.3389/fnmol.2017.00170
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- TBK1: a new player in ALS linking autophagy and neuroinflammation
- (2017) James A. Oakes et al. Molecular Brain
- Mammalian Autophagy: How Does It Work?
- (2016) Carla F. Bento et al. Annual Review of Biochemistry
- TARDBP/TDP-43 regulates autophagy in both MTORC1-dependent and MTORC1-independent manners
- (2016) Zheng Ying et al. Autophagy
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
- (2016) Daniel J Klionsky et al. Autophagy
- The role of CHMP2BIntron5 in autophagy and frontotemporal dementia
- (2016) Christopher S. Krasniak et al. BRAIN RESEARCH
- A novelDrosophilamodel of TDP-43 proteinopathies: N-terminal sequences combined with the Q/N domain induce protein functional loss and locomotion defects
- (2016) Simona Langellotti et al. Disease Models & Mechanisms
- Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin‐2 to induce motor neuron dysfunction and cell death
- (2016) Chantal Sellier et al. EMBO JOURNAL
- The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy
- (2016) Christopher P Webster et al. EMBO JOURNAL
- TFEB at a glance
- (2016) Gennaro Napolitano et al. JOURNAL OF CELL SCIENCE
- Physiological functions and pathobiology of TDP-43 and FUS/TLS proteins
- (2016) Antonia Ratti et al. JOURNAL OF NEUROCHEMISTRY
- Insights into the pathogenic mechanisms of Chromosome 9 open reading frame 72 (C9orf72) repeat expansions
- (2016) Tiffany W. Todd et al. JOURNAL OF NEUROCHEMISTRY
- The TORC1 pathway to protein destruction
- (2016) Lynne Chantranupong et al. NATURE
- Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria
- (2016) Benjamin Richter et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy
- (2016) M. Yang et al. Science Advances
- The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway
- (2016) Peter M. Sullivan et al. Acta Neuropathologica Communications
- Gene-specific mitochondria dysfunctions in human TARDBP and C9ORF72 fibroblasts
- (2016) Elisa Onesto et al. Acta Neuropathologica Communications
- Transcriptional induction of the heat shock protein B8 mediates the clearance of misfolded proteins responsible for motor neuron diseases
- (2016) Valeria Crippa et al. Scientific Reports
- TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins
- (2016) S. Prpar Mihevc et al. Scientific Reports
- Cerebellar c9RAN proteins associate with clinical and neuropathological characteristics of C9ORF72 repeat expansion carriers
- (2015) Tania F. Gendron et al. ACTA NEUROPATHOLOGICA
- Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism
- (2015) Wen-Chuan Shen et al. Autophagy
- TDP-43 loss of function increases TFEB activity and blocks autophagosome-lysosome fusion
- (2015) Q. Xia et al. EMBO JOURNAL
- p62/SQSTM1 functions as a signaling hub and an autophagy adaptor
- (2015) Yoshinori Katsuragi et al. FEBS Journal
- Autophagy and proteins involved in vesicular trafficking
- (2015) Celina Amaya et al. FEBS LETTERS
- TBK1 controls autophagosomal engulfment of polyubiquitinated mitochondria through p62/SQSTM1 phosphorylation
- (2015) Gen Matsumoto et al. HUMAN MOLECULAR GENETICS
- Reduced protein turnover mediates functional deficits in transgenic mice expressing the 25 kDa C-terminal fragment of TDP-43
- (2015) Antonella Caccamo et al. HUMAN MOLECULAR GENETICS
- Activation of ER Stress and Autophagy Induced by TDP-43 A315T as Pathogenic Mechanism and the Corresponding Histological Changes in Skin as Potential Biomarker for ALS with the Mutation
- (2015) Xuejing Wang et al. International Journal of Biological Sciences
- The functional and pathologic relevance of autophagy proteases
- (2015) Álvaro F. Fernández et al. JOURNAL OF CLINICAL INVESTIGATION
- C9orf72 expansions in frontotemporal dementia and amyotrophic lateral sclerosis
- (2015) Jonathan D Rohrer et al. LANCET NEUROLOGY
- Compromised autophagy and neurodegenerative diseases
- (2015) Fiona M. Menzies et al. NATURE REVIEWS NEUROSCIENCE
- TDP-43 affects splicing profiles and isoform production of genes involved in the apoptotic and mitotic cellular pathways
- (2015) Laura De Conti et al. NUCLEIC ACIDS RESEARCH
- The structural integrity of TDP-43 N-terminus is required for efficient aggregate entrapment and consequent loss of protein function
- (2015) Valentina Romano et al. Prion
- Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways
- (2015) E. T. Cirulli et al. SCIENCE
- Defining the genetic connection linking amyotrophic lateral sclerosis (ALS) with frontotemporal dementia (FTD)
- (2015) Serena Lattante et al. TRENDS IN GENETICS
- Compartment-dependent mitochondrial alterations in experimental ALS, the effects of mitophagy and mitochondriogenesis
- (2015) Gianfranco Natale et al. Frontiers in Cellular Neuroscience
- Age-related neurodegenerative disease research needs aging models
- (2015) Ian P. Johnson Frontiers in Aging Neuroscience
- Mitochondria-Associated Endoplasmic Reticulum Membranes Microenvironment: Targeting Autophagic and Apoptotic Pathways in Cancer Therapy
- (2015) Simone Patergnani et al. Frontiers in Oncology
- The role of TDP-43 in the pathogenesis of ALS and FTLD: Figure 1
- (2015) Marco Baralle et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Ageing and Parkinson's disease: Why is advancing age the biggest risk factor?
- (2014) Amy Reeve et al. AGEING RESEARCH REVIEWS
- Regulation of autophagy by amino acids and MTOR-dependent signal transduction
- (2014) Alfred J. Meijer et al. AMINO ACIDS
- Reduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson’s disease
- (2014) Karen E. Murphy et al. BRAIN
- The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration
- (2014) David Heras-Sandoval et al. CELLULAR SIGNALLING
- Targeting TDP-43 in neurodegenerative diseases
- (2014) Mauricio Budini et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- TDP-43 loss of cellular function through aggregation requires additional structural determinants beyond its C-terminal Q/N prion-like domain
- (2014) Mauricio Budini et al. HUMAN MOLECULAR GENETICS
- C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking
- (2014) Manal A. Farg et al. HUMAN MOLECULAR GENETICS
- Metabolism and mis-metabolism of the neuropathological signature protein TDP-43
- (2014) C.-C. Huang et al. JOURNAL OF CELL SCIENCE
- Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species
- (2014) E. L. Scotter et al. JOURNAL OF CELL SCIENCE
- Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models
- (2014) Sami J Barmada et al. Nature Chemical Biology
- Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation
- (2014) Yvette C. Wong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells
- (2014) I. Kwon et al. SCIENCE
- Ubiquitin pathways in neurodegenerative disease
- (2014) Graham Atkin et al. Frontiers in Molecular Neuroscience
- Emerging role of selective autophagy in human diseases
- (2014) Kenji Mizumura et al. Frontiers in Pharmacology
- Immunoreactivity of valosin-containing protein in sporadic amyotrophic lateral sclerosis and in a case of its novel mutant
- (2014) Takashi Ayaki et al. Acta Neuropathologica Communications
- Sporadic ALS with compound heterozygous mutations in the SQSTM1 gene
- (2013) Hiroshi Shimizu et al. ACTA NEUROPATHOLOGICA
- Homozygosity for the C9orf72 GGGGCC repeat expansion in frontotemporal dementia
- (2013) Pietro Fratta et al. ACTA NEUROPATHOLOGICA
- Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons
- (2013) Sandra Almeida et al. ACTA NEUROPATHOLOGICA
- Mutations in SQSTM1 encoding p62 in amyotrophic lateral sclerosis: genetics and neuropathology
- (2013) Elisa Teyssou et al. ACTA NEUROPATHOLOGICA
- Dissecting the role of the Atg12–Atg5-Atg16 complex during autophagosome formation
- (2013) Marta Walczak et al. Autophagy
- The ULK1 complex
- (2013) Pui-Mun Wong et al. Autophagy
- The product of C9orf72, a gene strongly implicated in neurodegeneration, is structurally related to DENN Rab-GEFs
- (2013) Timothy P. Levine et al. BIOINFORMATICS
- New hope for therapy in neurodegenerative diseases
- (2013) Maria do Carmo Costa et al. CELL RESEARCH
- Autophagy regulation by nutrient signaling
- (2013) Ryan C Russell et al. CELL RESEARCH
- TARDBPandFUSMutations Associated with Amyotrophic Lateral Sclerosis: Summary and Update
- (2013) Serena Lattante et al. HUMAN MUTATION
- Alternative fates of newly formed PrPSc upon prion conversion on the plasma membrane
- (2013) R. Goold et al. JOURNAL OF CELL SCIENCE
- Autophagosomes form at ER–mitochondria contact sites
- (2013) Maho Hamasaki et al. NATURE
- The autophagosome: origins unknown, biogenesis complex
- (2013) Christopher A. Lamb et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia
- (2013) T. Zu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Connections between SNAREs and autophagy
- (2013) Kevin Moreau et al. TRENDS IN BIOCHEMICAL SCIENCES
- Current insights into the C9orf72 repeat expansion diseases of the FTLD/ALS spectrum
- (2013) Marc Cruts et al. TRENDS IN NEUROSCIENCES
- SQSTM1Mutations in French Patients With Frontotemporal Dementia or Frontotemporal Dementia With Amyotrophic Lateral Sclerosis
- (2013) Isabelle Le Ber JAMA Neurology
- The plasma membrane as a control center for autophagy
- (2012) Kevin Moreau et al. Autophagy
- Clinico-pathological features in amyotrophic lateral sclerosis with expansions in C9ORF72
- (2012) Johnathan Cooper-Knock et al. BRAIN
- Role of selected mutations in the Q/N rich region of TDP-43 in EGFP-12xQ/N-induced aggregate formation
- (2012) Mauricio Budini et al. BRAIN RESEARCH
- Neuronal ceroid lipofuscinosis protein CLN3 interacts with motor proteins and modifies location of late endosomal compartments
- (2012) Kristiina Uusi-Rauva et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Autoregulation of TDP-43 mRNA levels involves interplay between transcription, splicing, and alternative polyA site selection
- (2012) S. E. Avendano-Vazquez et al. GENES & DEVELOPMENT
- Cellular Model of TAR DNA-binding Protein 43 (TDP-43) Aggregation Based on Its C-terminal Gln/Asn-rich Region
- (2012) Mauricio Budini et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Microtubule-associated Protein 1 Light Chain 3 (LC3) Interacts with Bnip3 Protein to Selectively Remove Endoplasmic Reticulum and Mitochondria via Autophagy
- (2012) Rita A. Hanna et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cdc37/Hsp90 Protein Complex Disruption Triggers an Autophagic Clearance Cascade for TDP-43 Protein
- (2012) Umesh K. Jinwal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Endogenous TDP-43, but not FUS, contributes to stress granule assembly via G3BP
- (2012) Anaïs Aulas et al. Molecular Neurodegeneration
- Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy
- (2012) Chinatsu Otomo et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Full-length TDP-43 and its C-terminal fragments activate mitophagy in NSC34 cell line
- (2012) Kun Hong et al. NEUROSCIENCE LETTERS
- Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43
- (2012) I.-F. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDP-43: gumming up neurons through protein–protein and protein–RNA interactions
- (2012) Emanuele Buratti et al. TRENDS IN BIOCHEMICAL SCIENCES
- Clinical aspects of palliative care in advanced Parkinson’s disease
- (2012) Johan Lokk et al. BMC Palliative Care
- Discovery of Novel DENN Proteins: Implications for the Evolution of Eukaryotic Intracellular Membrane Structures and Human Disease
- (2012) Dapeng Zhang et al. Frontiers in Genetics
- Neuronal Autophagy: A Housekeeper or a Fighter in Neuronal Cell Survival?
- (2012) Jin-A Lee Experimental Neurobiology
- p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS
- (2011) Safa Al-Sarraj et al. ACTA NEUROPATHOLOGICA
- SQSTM1 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2011) Faisal Fecto ARCHIVES OF NEUROLOGY
- RalB and the Exocyst Mediate the Cellular Starvation Response by Direct Activation of Autophagosome Assembly
- (2011) Brian O. Bodemann et al. CELL
- Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies
- (2011) Joseph R. Mazzulli et al. CELL
- Removing Protein Aggregates: The Role of Proteolysis in Neurodegeneration
- (2011) D. A.T. Nijholt et al. CURRENT MEDICINAL CHEMISTRY
- Roles of the Drosophila LRRK2 homolog in Rab7-dependent lysosomal positioning
- (2011) M. W. Dodson et al. HUMAN MOLECULAR GENETICS
- Regulation of Autophagy by Neuropathological Protein TDP-43
- (2011) Jayarama Krishnan Bose et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autophagy in Spinal Cord Motor Neurons in Sporadic Amyotrophic Lateral Sclerosis
- (2011) Shoichi Sasaki JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Lysosomal Proteolysis Inhibition Selectively Disrupts Axonal Transport of Degradative Organelles and Causes an Alzheimer's-Like Axonal Dystrophy
- (2011) S. Lee et al. JOURNAL OF NEUROSCIENCE
- AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
- (2011) Joungmok Kim et al. NATURE CELL BIOLOGY
- Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration
- (2011) Edward B. Lee et al. NATURE REVIEWS NEUROSCIENCE
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
- (2011) Alan E. Renton et al. NEURON
- An MND/ALS phenotype associated withC9orf72repeat expansion: Abundant p62-positive, TDP-43-negative inclusions in cerebral cortex, hippocampus and cerebellum but without associated cognitive decline
- (2011) Claire Troakes et al. NEUROPATHOLOGY
- Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins
- (2010) Eisuke Itakura et al. Autophagy
- Nix: A receptor protein for mitophagy in mammals
- (2010) Tomotake Kanki Autophagy
- A role of small heat shock protein B8 (HspB8) in the autophagic removal of misfolded proteins responsible for neurodegenerative diseases
- (2010) Valeria Crippa et al. Autophagy
- Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation
- (2010) Hannah E.J. Polson et al. Autophagy
- Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation
- (2010) Dale W. Hailey et al. CELL
- Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders
- (2010) Alessandro Fraldi et al. EMBO JOURNAL
- TDP-43 regulates its mRNA levels through a negative feedback loop
- (2010) Youhna M Ayala et al. EMBO JOURNAL
- The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS)
- (2010) Valeria Crippa et al. HUMAN MOLECULAR GENETICS
- Interaction with Polyglutamine Aggregates Reveals a Q/N-rich Domain in TDP-43
- (2010) Rodrigo A. Fuentealba et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- α-Synuclein impairs macroautophagy: implications for Parkinson’s disease
- (2010) Ashley R. Winslow et al. JOURNAL OF CELL BIOLOGY
- The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy
- (2010) Sabrina Di Bartolomeo et al. JOURNAL OF CELL BIOLOGY
- TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
- (2010) Ian RA Mackenzie et al. LANCET NEUROLOGY
- Post-Golgi Sec Proteins Are Required for Autophagy in Saccharomyces cerevisiae
- (2010) Jiefei Geng et al. MOLECULAR BIOLOGY OF THE CELL
- Network organization of the human autophagy system
- (2010) Christian Behrends et al. NATURE
- Mutations of optineurin in amyotrophic lateral sclerosis
- (2010) Hirofumi Maruyama et al. NATURE
- Plasma membrane contributes to the formation of pre-autophagosomal structures
- (2010) Brinda Ravikumar et al. NATURE CELL BIOLOGY
- Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease
- (2010) Marta Martinez-Vicente et al. NATURE NEUROSCIENCE
- Ubiquitinated, p62 immunopositive cerebellar cortical neuronal inclusions are evident across the spectrum of TDP-43 proteinopathies but are only rarely additionally immunopositive for phosphorylation-dependent TDP-43
- (2010) Andrew King et al. NEUROPATHOLOGY
- The tuberous sclerosis complex
- (2009) Ksenia A. Orlova et al. Annals of the New York Academy of Sciences
- Autophagy defects contribute to neurodegeneration induced by dysfunctional ESCRT-III
- (2009) Jin-A Lee et al. Autophagy
- 3D tomography reveals connections between the phagophore and endoplasmic reticulum
- (2009) Päivi Ylä-Anttila et al. Autophagy
- TDP-43 Is Intrinsically Aggregation-prone, and Amyotrophic Lateral Sclerosis-linked Mutations Accelerate Aggregation and Increase Toxicity
- (2009) Brian S. Johnson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Rapamycin Rescues TDP-43 Mislocalization and the Associated Low Molecular Mass Neurofilament Instability
- (2009) Antonella Caccamo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Synergistic effect between proteasome and autophagosome in the clearance of polyubiquitinated TDP-43
- (2009) Makoto Urushitani et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Autophagy, lithium, and amyotrophic lateral sclerosis
- (2009) Livia Pasquali et al. MUSCLE & NERVE
- A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation
- (2009) Mitsuko Hayashi-Nishino et al. NATURE CELL BIOLOGY
- Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1–phosphatidylinositol-3-kinase complex
- (2009) Yun Zhong et al. NATURE CELL BIOLOGY
- TDP-43 is consistently co-localized with ubiquitinated inclusions in sporadic and Guam amyotrophic lateral sclerosis but not in familial amyotrophic lateral sclerosis with and without SOD1 mutations
- (2009) Satomi Maekawa et al. NEUROPATHOLOGY
- Degradation of TDP-43 and its pathogenic form by autophagy and the ubiquitin-proteasome system
- (2009) Xiaoju Wang et al. NEUROSCIENCE LETTERS
- Functional mapping of the interaction between TDP-43 and hnRNP A2 in vivo
- (2009) A. D'Ambrogio et al. NUCLEIC ACIDS RESEARCH
- Structural insights into TDP-43 in nucleic-acid binding and domain interactions
- (2009) P.-H. Kuo et al. NUCLEIC ACIDS RESEARCH
- Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity
- (2009) Y.-J. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- White matter lesions in the brain with frontotemporal lobar degeneration with motor neuron disease: TDP-43-immunopositive inclusions co-localize with p62, but not ubiquitin
- (2008) Masanori Hiji et al. ACTA NEUROPATHOLOGICA
- Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
- (2008) Masato Hasegawa et al. ANNALS OF NEUROLOGY
- Abnormal phosphorylation of Ser409/410 of TDP-43 in FTLD-U and ALS
- (2008) Yuki Inukai et al. FEBS LETTERS
- Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
- (2008) Elizabeth L. Axe et al. JOURNAL OF CELL BIOLOGY
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
- FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells
- (2008) Taichi Hara et al. JOURNAL OF CELL BIOLOGY
- Structural determinants of the cellular localization and shuttling of TDP-43
- (2008) Y. M. Ayala et al. JOURNAL OF CELL SCIENCE
- The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid β accumulation in mice
- (2008) Fiona Pickford et al. JOURNAL OF CLINICAL INVESTIGATION
- Functional Characterization of Rab7 Mutant Proteins Associated with Charcot-Marie-Tooth Type 2B Disease
- (2008) M. R. Spinosa et al. JOURNAL OF NEUROSCIENCE
- AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
- (2008) Dana M. Gwinn et al. MOLECULAR CELL
- A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity
- (2008) B. S. Johnson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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