miR-122 inhibition in a human liver organoid model leads to liver inflammation, necrosis, steatofibrosis and dysregulated insulin signaling
出版年份 2018 全文链接
标题
miR-122 inhibition in a human liver organoid model leads to liver inflammation, necrosis, steatofibrosis and dysregulated insulin signaling
作者
关键词
Organoids, Fatty liver, Hepatocytes, Fibrosis, Liver fibrosis, Lentivirus, Inflammation, Insulin signaling
出版物
PLoS One
Volume 13, Issue 7, Pages e0200847
出版商
Public Library of Science (PLoS)
发表日期
2018-07-20
DOI
10.1371/journal.pone.0200847
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention
- (2017) Zobair Younossi et al. Nature Reviews Gastroenterology & Hepatology
- Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform
- (2017) Aleksander Skardal et al. Scientific Reports
- Novel 3D Culture Systems for Studies of Human Liver Function and Assessments of the Hepatotoxicity of Drugs and Drug Candidates
- (2016) Volker M. Lauschke et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Organoid-on-a-chip and body-on-a-chip systems for drug screening and disease modeling
- (2016) Aleksander Skardal et al. DRUG DISCOVERY TODAY
- Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes
- (2016) Zobair M. Younossi et al. HEPATOLOGY
- Molecular Pathogenesis of NASH
- (2016) Alessandra Caligiuri et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Regulation of plasma lipid homeostasis by hepatic lipoprotein lipase in adult mice
- (2016) Gan Liu et al. JOURNAL OF LIPID RESEARCH
- Reciprocal Regulation between SIRT6 and miR-122 Controls Liver Metabolism and Predicts Hepatocarcinoma Prognosis
- (2016) Sivan Elhanati et al. Cell Reports
- Concise Review: Organoids Are a Powerful Tool for the Study of Liver Disease and Personalized Treatment Design in Humans and Animals
- (2016) Sathidpak Nantasanti et al. Stem Cells Translational Medicine
- Antifibrotic Effects of the Dual CCR2/CCR5 Antagonist Cenicriviroc in Animal Models of Liver and Kidney Fibrosis
- (2016) Eric Lefebvre et al. PLoS One
- Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease
- (2016) Catherine C. Bell et al. Scientific Reports
- miR-122 is a Unique Molecule with Great Potential in Diagnosis, Prognosis of Liver Disease, and Therapy Both as miRNA Mimic and Antimir
- (2015) Sharda Thakral et al. CURRENT GENE THERAPY
- miR-122 – A key factor and therapeutic target in liver disease
- (2015) Simonetta Bandiera et al. JOURNAL OF HEPATOLOGY
- Reversibility of liver fibrosis
- (2015) Mengxi Sun et al. Clinics and Research in Hepatology and Gastroenterology
- Identification of a novel TGF-β-miR-122-fibronectin 1/serum response factor signaling cascade and its implication in hepatic fibrogenesis
- (2015) Chunxian Zeng et al. Oncotarget
- microRNA-122 regulates hypoxia-inducible factor-1 and vimentin in hepatocytes and correlates with fibrosis in diet-induced steatohepatitis
- (2014) Timea Csak et al. LIVER INTERNATIONAL
- Liver fatty acid-binding protein as a diagnostic marker for non-alcoholic fatty liver disease
- (2014) Erdem Akbal et al. WIENER KLINISCHE WOCHENSCHRIFT
- Moderate GLUT4 Overexpression Improves Insulin Sensitivity and Fasting Triglyceridemia in High-Fat Diet-Fed Transgenic Mice
- (2013) B. J. Atkinson et al. DIABETES
- The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver disease
- (2013) Victoria L. Gadd et al. HEPATOLOGY
- Circulating microRNA 122 in the methionine and choline-deficient mouse model of non-alcoholic steatohepatitis
- (2013) John D. Clarke et al. JOURNAL OF APPLIED TOXICOLOGY
- Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2
- (2012) K. D. Copps et al. DIABETOLOGIA
- Dual Role of miR-122 in Molecular Pathogenesis of Viral Hepatitis
- (2012) Hossein Sendi Hepatitis Monthly
- miR-122 regulates hepatic lipid metabolism and tumor suppression
- (2012) Jessica Wen et al. JOURNAL OF CLINICAL INVESTIGATION
- Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver
- (2012) Shu-hao Hsu et al. JOURNAL OF CLINICAL INVESTIGATION
- MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis
- (2012) Wei-Chih Tsai et al. JOURNAL OF CLINICAL INVESTIGATION
- miR-122 regulates collagen production via targeting hepatic stellate cells and suppressing P4HA1 expression
- (2012) Jiang Li et al. JOURNAL OF HEPATOLOGY
- Hepatic expression and cellular distribution of the glucose transporter family
- (2012) Sumera Karim WORLD JOURNAL OF GASTROENTEROLOGY
- Elevated systemic monocyte chemoattractrant protein-1 in hepatic steatosis without significant hepatic inflammation
- (2011) Georgi Kirovski et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Increased Hepatic and Circulating Interleukin-6 Levels in Human Nonalcoholic Steatohepatitis
- (2008) Anna Wieckowska et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- A Stress Signaling Pathway in Adipose Tissue Regulates Hepatic Insulin Resistance
- (2008) G. Sabio et al. SCIENCE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started