The long noncoding RNA H19 promotes tamoxifen resistance in breast cancer via autophagy

MTA1 is a novel regulator of autophagy that induces tamoxifen resistance in breast cancer cells

(2018) Min-Ho Lee et al.   Autophagy

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

KLF4 overcomes tamoxifen resistance by suppressing MAPK signaling pathway and predicts good prognosis in breast cancer

(2018) Yunlu Jia et al.   CELLULAR SIGNALLING

Life, death and autophagy

(2018) Johnna Doherty et al.   NATURE CELL BIOLOGY

Acquired HER2 mutations in ER+ metastatic breast cancer confer resistance to estrogen receptor–directed therapies

(2018) Utthara Nayar et al.   NATURE GENETICS

Long noncoding RNA H19 mediated the chemosensitivity of breast cancer cells via Wnt pathway and EMT process

(2018) Hongli Gao et al.   OncoTargets and Therapy

Long noncoding RNA EGFR-AS1 mediates epidermal growth factor receptor addiction and modulates treatment response in squamous cell carcinoma

(2017) Daniel S W Tan et al.   NATURE MEDICINE

The lncRNA H19 mediates breast cancer cell plasticity during EMT and MET plasticity by differentially sponging miR-200b/c and let-7b

(2017) Wu Zhou et al.   Science Signaling

H19/let-7/LIN28 reciprocal negative regulatory circuit promotes breast cancer stem cell maintenance

(2017) Fei Peng et al.   Cell Death & Disease

The lncRNA H19 mediates breast cancer cell plasticity during EMT and MET plasticity by differentially sponging miR-200b/c and let-7b

(2017) Wu Zhou et al.   Science Signaling

Long Non-coding RNA H19 Induces Cerebral Ischemia Reperfusion Injury via Activation of Autophagy

(2017) Jue Wang et al.   Aging and Disease

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

PlasmaESR1Mutations and the Treatment of Estrogen Receptor–Positive Advanced Breast Cancer

(2016) Charlotte Fribbens et al.   JOURNAL OF CLINICAL ONCOLOGY

The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression

(2016) Yashar S. Niknafs et al.   Nature Communications

LncRNA H19 inhibits autophagy by epigenetically silencing of DIRAS3 in diabetic cardiomyopathy

(2016) Chuanjun Zhuo et al.   Oncotarget

Estrogen regulates luminal progenitor cell differentiation throughH19gene expression

(2015) Pratima Basak et al.   ENDOCRINE-RELATED CANCER

Differentiation of mammary tumors and reduction in metastasis uponMalat1lncRNA loss

(2015) Gayatri Arun et al.   GENES & DEVELOPMENT

The role for autophagy in cancer

(2015) Eileen White   JOURNAL OF CLINICAL INVESTIGATION

Long non-coding RNA chromogenic in situ hybridisation signal pattern correlation with breast tumour pathology

(2015) Zhouwei Zhang et al.   JOURNAL OF CLINICAL PATHOLOGY

The H19 Long non-coding RNA in cancer initiation, progression and metastasis – a proposed unifying theory

(2015) Eli Raveh et al.   Molecular Cancer

LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer

(2015) X Xue et al.   ONCOGENE

H19 lncRNA mediates 17β-estradiol-induced cell proliferation in MCF-7 breast cancer cells

(2015) HONG SUN et al.   ONCOLOGY REPORTS

Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer

(2015) Gaia Schiavon et al.   Science Translational Medicine

H19 lncRNA alters DNA methylation genome wide by regulating S-adenosylhomocysteine hydrolase

(2015) Jichun Zhou et al.   Nature Communications

Autophagy revisited: A conversation with Christian de Duve

(2014) Daniel J. Klionsky   Autophagy

Global Gene Repression by the Steroid Receptor Coactivator SRC-1 Promotes Oncogenesis

(2014) C. A. Walsh et al.   CANCER RESEARCH

Emergence of Constitutively Active Estrogen Receptor-  Mutations in Pretreated Advanced Estrogen Receptor-Positive Breast Cancer

(2014) R. Jeselsohn et al.   CLINICAL CANCER RESEARCH

Chloroquine Inhibits Autophagy to Potentiate Antiestrogen Responsiveness in ER+ Breast Cancer

(2014) K. L. Cook et al.   CLINICAL CANCER RESEARCH

Adjuvant Endocrine Therapy for Women With Hormone Receptor–Positive Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline Focused Update

(2014) Harold J. Burstein et al.   JOURNAL OF CLINICAL ONCOLOGY

Regulation of tumor cell migration and invasion by the H19/let-7 axis is antagonized by metformin-induced DNA methylation

(2014) L Yan et al.   ONCOGENE

Methionine Inhibits Autophagy and Promotes Growth by Inducing the SAM-Responsive Methylation of PP2A

(2013) Benjamin M. Sutter et al.   CELL

lincRNAs: Genomics, Evolution, and Mechanisms

(2013) Igor Ulitsky et al.   CELL

Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials

(2013)   LANCET

Estrogen receptor-α36 is involved in development of acquired tamoxifen resistance via regulating the growth status switch in breast cancer cells

(2013) Guangliang Li et al.   Molecular Oncology

The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex

(2013) John R Prensner et al.   NATURE GENETICS

Autophagy Sustains Mitochondrial Glutamine Metabolism and Growth of BrafV600E-Driven Lung Tumors

(2013) A. M. Strohecker et al.   Cancer Discovery

Improving Endocrine Therapy for Breast Cancer: It's Not That Simple

(2012) E. Claire Dees et al.   JOURNAL OF CLINICAL ONCOLOGY

Protocadherin 17 acts as a tumour suppressor inducing tumour cell apoptosis and autophagy, and is frequently methylated in gastric and colorectal cancers

(2012) Xiaotong Hu et al.   JOURNAL OF PATHOLOGY

The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r

(2012) Andrew Keniry et al.   NATURE CELL BIOLOGY

A transcriptional variant of the LC3A gene is involved in autophagy and frequently inactivated in human cancers

(2012) H Bai et al.   ONCOGENE

Autophagy and endocrine resistance in breast cancer

(2011) Katherine L Cook et al.   Expert Review of Anticancer Therapy

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis

(2011) J. Y. Guo et al.   GENES & DEVELOPMENT

High-throughput ectopic expression screen for tamoxifen resistance identifies an atypical kinase that blocks autophagy

(2011) Laura Gonzalez-Malerva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Emergence of lncRNAs in Cancer Biology

(2011) J. R. Prensner et al.   Cancer Discovery

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

(2010) Maite Huarte et al.   CELL

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer

(2009) Wing Pui Tsang et al.   CARCINOGENESIS

Efficient oligonucleotide-mediated degradation of nuclear noncoding RNAs in mammalian cultured cells

(2009) T. Ideue et al.   RNA

Macroautophagy inhibition sensitizes tamoxifen-resistant breast cancer cells and enhances mitochondrial depolarization

(2008) M. A. Qadir et al.   BREAST CANCER RESEARCH AND TREATMENT

Regulation of Estrogenic Effects by Beclin 1 in Breast Cancer Cells

(2008) S. John et al.   CANCER RESEARCH

Crosstalk between the Estrogen Receptor and the HER Tyrosine Kinase Receptor Family: Molecular Mechanism and Clinical Implications for Endocrine Therapy Resistance

(2008) Grazia Arpino et al.   ENDOCRINE REVIEWS

A role for macroautophagy in protection against 4-hydroxytamoxifen-induced cell death and the development of antiestrogen resistance

(2008) J. S. Samaddar et al.   MOLECULAR CANCER THERAPEUTICS