Beyond N-Cadherin, Relevance of Cadherins 5, 6 and 17 in Cancer Progression and Metastasis

RGD cadherins and α2β1 integrin in cancer metastasis: A dangerous liaison

(2018) J. Ignacio Casal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

TEMPORARY REMOVAL: CDH17 alters MMP-2 expression via canonical NF-κB signalling in human gastric cancer

(2018) Xiao-jie Jiang et al.   GENE

miR-223-3p Inhibits Human Osteosarcoma Metastasis and Progression by Directly Targeting CDH6

(2018) Quanbo Ji et al.   MOLECULAR THERAPY

N-cadherin in cancer metastasis, its emerging role in haematological malignancies and potential as a therapeutic target in cancer

(2018) Krzysztof Marek Mrozik et al.   BMC CANCER

Combined miRNA profiling and proteomics demonstrates that different miRNAs target a common set of proteins to promote colorectal cancer metastasis

(2017) Sofía Torres et al.   JOURNAL OF PATHOLOGY

Cadherin composition and multicellular aggregate invasion in organotypic models of epithelial ovarian cancer intraperitoneal metastasis

(2017) Y Klymenko et al.   ONCOGENE

Identification and Validation of Novel Subtype-Specific Protein Biomarkers in Pancreatic Ductal Adenocarcinoma

(2017) Laura Kuhlmann et al.   PANCREAS

A pathology atlas of the human cancer transcriptome

(2017) Mathias Uhlen et al.   SCIENCE

Discovery and Optimization of HKT288, a Cadherin-6–Targeting ADC for the Treatment of Ovarian and Renal Cancers

(2017) Carl U. Bialucha et al.   Cancer Discovery

Cadherins Associate with Distinct Stem Cell-Related Transcription Factors to Coordinate the Maintenance of Stemness in Triple-Negative Breast Cancer

(2017) Chuanwei Yang et al.   Stem Cells International

Cadherin 6 is activated by Epstein–Barr virus LMP1 to mediate EMT and metastasis as an interplay node of multiple pathways in nasopharyngeal carcinoma

(2017) L-L Zuo et al.   Oncogenesis

Cadherin-5: a biomarker for metastatic breast cancer with optimum efficacy in oestrogen receptor-positive breast cancers with vascular invasion

(2016) Simon A Fry et al.   BRITISH JOURNAL OF CANCER

Cadherin-6 is a putative tumor suppressor and target of epigenetically dysregulated miR-429 in cholangiocarcinoma

(2016) Benjamin Goeppert et al.   Epigenetics

Cadherin 5 expression correlates with poor survival in human gastric cancer

(2016) Kyoko Higuchi et al.   JOURNAL OF CLINICAL PATHOLOGY

Cadherin-6 promotes EMT and cancer metastasis by restraining autophagy

(2016) M Gugnoni et al.   ONCOGENE

Epidermal Growth Factor Receptor Mutation Enhances Expression of Cadherin-5 in Lung Cancer Cells

(2016) Ming-Szu Hung et al.   PLoS One

Cadherin tales: Regulation of cadherin function by endocytic membrane trafficking

(2016) Chantel M. Cadwell et al.   TRAFFIC

Candidate genes and pathways downstream of PAX8 involved in ovarian high-grade serous carcinoma

(2016) Tiziana de Cristofaro et al.   Oncotarget

VE-cadherin RGD motifs promote metastasis and constitute a potential therapeutic target in melanoma and breast cancers

(2016) Rubén A. Bartolomé et al.   Oncotarget

Interplay between cadherins and α2β1 integrin differentially regulates melanoma cell invasion

(2015) Carole Siret et al.   BRITISH JOURNAL OF CANCER

Soluble VE-cadherin is involved in endothelial barrier breakdown in systemic inflammation and sepsis

(2015) S. Flemming et al.   CARDIOVASCULAR RESEARCH

Concomitant high expression of BRAFV600E, P-cadherin and cadherin 6 is associated with High TNM stage and lymph node metastasis in conventional papillary thyroid carcinoma

(2015) Le Zhao et al.   CLINICAL ENDOCRINOLOGY

Expression of cadherin 17 in well-differentiated neuroendocrine tumours

(2015) Anthony N Snow et al.   HISTOPATHOLOGY

β-Catenin is required for intrinsic but not extrinsic BCR-ABL1 kinase-independent resistance to tyrosine kinase inhibitors in chronic myeloid leukemia

(2015) A M Eiring et al.   LEUKEMIA

Alpha2beta1 integrin in cancer development and chemoresistance

(2015) Dalila Naci et al.   SEMINARS IN CANCER BIOLOGY

Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance

(2015) Laetitia Seguin et al.   TRENDS IN CELL BIOLOGY

Cadherin 17 is a Novel Diagnostic Marker for Adenocarcinomas of the Digestive System

(2014) Nelson G. Ordóñez   ADVANCES IN ANATOMIC PATHOLOGY

Cadherin 17 is frequently expressed by ‘sclerosing variant’ pancreatic neuroendocrine tumour

(2014) Adam Johnson et al.   HISTOPATHOLOGY

An RGD Motif Present in Cadherin 17 Induces Integrin Activation and Tumor Growth

(2014) Rubén A. Bartolomé et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stromal cells attenuate the cytotoxicity of imatinib on Philadelphia chromosome-positive leukemia cells by up-regulating the VE-cadherin/β-catenin signal

(2014) Chong Chen et al.   LEUKEMIA RESEARCH

Cadherin-17 induces tumorigenesis and lymphatic metastasis in gastric cancer through activation of NFκB signaling pathway

(2013) Jin Wang et al.   CANCER BIOLOGY & THERAPY

VE-Cadherin and Endothelial Adherens Junctions: Active Guardians of Vascular Integrity

(2013) Monica Giannotta et al.   DEVELOPMENTAL CELL

Tumour vasculogenic mimicry is associated with poor prognosis of human cancer patients: A systemic review and meta-analysis

(2013) Zhifei Cao et al.   EUROPEAN JOURNAL OF CANCER

Distinguishing primary adenocarcinoma of the urinary bladder from secondary involvement by colorectal adenocarcinoma: extended immunohistochemical profiles emphasizing novel markers

(2013) Qiu Rao et al.   MODERN PATHOLOGY

CDH5 is specifically activated in glioblastoma stemlike cells and contributes to vasculogenic mimicry induced by hypoxia

(2013) X.-g. Mao et al.   NEURO-ONCOLOGY

Cadherin-17 interacts with α2β1 integrin to regulate cell proliferation and adhesion in colorectal cancer cells causing liver metastasis

(2013) R A Bartolomé et al.   ONCOGENE

Cadherin 6 Is a New RUNX2 Target in TGF-β Signalling Pathway

(2013) Valentina Sancisi et al.   PLoS One

Cadherin 6 Has a Functional Role in Platelet Aggregation and Thrombus Formation

(2012) Eimear Dunne et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

LI-cadherin cis-dimerizes in the plasma membrane Ca2+ independently and forms highly dynamic trans-contacts

(2012) Thilo Bartolmäs et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Molecular Profiling of Pancreatic Neuroendocrine Tumors in Sporadic and Von Hippel-Lindau Patients

(2012) D. Speisky et al.   CLINICAL CANCER RESEARCH

Up-Regulation of Cadherin 17 and Down-Regulation of Homeodomain Protein CDX2 Correlate With Tumor Progression and Unfavorable Prognosis in Epithelial Ovarian Cancer

(2012) Li-Ping Huang et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Tumor Metastasis: Molecular Insights and Evolving Paradigms

(2011) Scott Valastyan et al.   CELL

Comparison of cadherin-17 expression between primary colorectal adenocarcinomas and their corresponding metastases: the possibility of a diagnostic marker for detecting the primary site of metastatic tumour

(2011) Jong Hyeok Park et al.   HISTOPATHOLOGY

Integrins and cadherins join forces to form adhesive networks

(2011) G. F. Weber et al.   JOURNAL OF CELL SCIENCE

Prospective Multicenter Phase II Trial of Systemic ADH-1 in Combination With Melphalan via Isolated Limb Infusion in Patients With Advanced Extremity Melanoma

(2011) Georgia M. Beasley et al.   JOURNAL OF CLINICAL ONCOLOGY

The function of 7D-cadherins: a mathematical model predicts physiological importance for water transport through simple epithelia

(2011) Mareike Ahl et al.   Theoretical Biology and Medical Modelling

The Function of E-Cadherin in Stem Cell Pluripotency and Self-Renewal

(2011) Francesca Soncin et al.   Genes

Inhibitor of DNA binding-1 induces mesenchymal features and promotes invasiveness in thyroid tumour cells

(2010) Alessia Ciarrocchi et al.   EUROPEAN JOURNAL OF CANCER

VE-cadherin and PECAM-1 enhance ALL migration across brain microvascular endothelial cell monolayers

(2010) Stephen M. Akers et al.   EXPERIMENTAL HEMATOLOGY

Glioblastoma stem-like cells give rise to tumour endothelium

(2010) Rong Wang et al.   NATURE

Liver-intestine cadherin predicts microvascular invasion and poor prognosis of hepatitis B virus-positive hepatocellular carcinoma

(2009) Zhen-Bin Ding et al.   CANCER

Galectin-3 Mediates Nuclear β-Catenin Accumulation and Wnt Signaling in Human Colon Cancer Cells by Regulation of Glycogen Synthase Kinase-3β Activity

(2009) Shumei Song et al.   CANCER RESEARCH

Integrin  2 Mediates Selective Metastasis to the Liver

(2009) K. Yoshimura et al.   CANCER RESEARCH

The Platelet Integrin αIIbβ3 Binds to the RGD and AGD Motifs in Fibrinogen

(2009) Juan Sánchez-Cortés et al.   CHEMISTRY & BIOLOGY

Targeting cadherin-17 inactivates Wnt signaling and inhibits tumor growth in liver carcinoma

(2009) Ling Xiao Liu et al.   HEPATOLOGY

Involvement of Members of the Cadherin Superfamily in Cancer

(2009) G. Berx et al.   Cold Spring Harbor Perspectives in Biology

Vascular Endothelial Cadherin Promotes Breast Cancer Progression via Transforming Growth Factor   Signaling

(2008) M. Labelle et al.   CANCER RESEARCH

The cell-cell adhesion molecule E-cadherin

(2008) F. van Roy et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cadherin switching

(2008) M. J. Wheelock et al.   JOURNAL OF CELL SCIENCE

Heterotypic trans-Interaction of LI- and E-Cadherin and Their Localization in Plasmalemmal Microdomains

(2008) Werner Baumgartner et al.   JOURNAL OF MOLECULAR BIOLOGY

Cadherin-17 is a useful diagnostic marker for adenocarcinomas of the digestive system

(2008) Min-Cheng Su et al.   MODERN PATHOLOGY

Ovarian Carcinoma Subtypes Are Different Diseases: Implications for Biomarker Studies

(2008) Martin Köbel et al.   PLOS MEDICINE