CDH5 is specifically activated in glioblastoma stemlike cells and contributes to vasculogenic mimicry induced by hypoxia

RhoJ is an endothelial cell-restricted Rho GTPase that mediates vascular morphogenesis and is regulated by the transcription factor ERG

(2011) L. Yuan et al.   BLOOD

Overexpression of ZNF217 in glioblastoma contributes to the maintenance of glioma stem cells regulated by hypoxia-inducible factors

(2011) Xing-gang Mao et al.   LABORATORY INVESTIGATION

Transdifferentiation of glioblastoma cells into vascular endothelial cells

(2011) Y. Soda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma

(2011) Olivier Keunen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia Increases the Expression of Stem-Cell Markers and Promotes Clonogenicity in Glioblastoma Neurospheres

(2010) Eli E. Bar et al.   AMERICAN JOURNAL OF PATHOLOGY

A new alternative mechanism in glioblastoma vascularization: tubular vasculogenic mimicry

(2010) S. El Hallani et al.   BRAIN

A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2α

(2010) Sascha Seidel et al.   BRAIN

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

(2010) John M. Heddleston et al.   CELL CYCLE

Perivascular Nitric Oxide Activates Notch Signaling and Promotes Stem-like Character in PDGF-Induced Glioma Cells

(2010) Nikki Charles et al.   Cell Stem Cell

Maintenance of Critical Properties of Brain Tumor Stem-like Cells After Cryopreservation

(2010) Xing-gang Mao et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Vascular gene expression patterns are conserved in primary and metastatic brain tumors

(2010) Yang Liu et al.   JOURNAL OF NEURO-ONCOLOGY

Knock down of HIF-1α in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres

(2010) Olga Méndez et al.   Molecular Cancer

Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells

(2010) Lucia Ricci-Vitiani et al.   NATURE

Glioblastoma stem-like cells give rise to tumour endothelium

(2010) Rong Wang et al.   NATURE

O2 regulates stem cells through Wnt/β-catenin signalling

(2010) Jolly Mazumdar et al.   NATURE CELL BIOLOGY

Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells

(2009) Zhizhong Li et al.   CANCER CELL

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

Intrinsic Gene Expression Profiles of Gliomas Are a Better Predictor of Survival than Histology

(2009) L. A.M. Gravendeel et al.   CANCER RESEARCH

Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts

(2009) David R. Mole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The transcriptional network for mesenchymal transformation of brain tumours

(2009) Maria Stella Carro et al.   NATURE

Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1α

(2009) A Soeda et al.   ONCOGENE

Preferential binding of HIF-1 to transcriptionally active loci determines cell-type specific response to hypoxia

(2009) Xiaobo Xia et al.   GENOME BIOLOGY

Identification of a Core Set of 58 Gene Transcripts With Broad and Specific Expression in the Microvasculature

(2008) Elisabet Wallgard et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin

(2008) G. M. Birdsey et al.   BLOOD

Gene expression analysis of glioblastomas identifies the major molecular basis for the prognostic benefit of younger age

(2008) Yohan Lee et al.   BMC Medical Genomics

Vascular Endothelial Cadherin Promotes Breast Cancer Progression via Transforming Growth Factor   Signaling

(2008) M. Labelle et al.   CANCER RESEARCH

Progress on Potential Strategies to Target Brain Tumor Stem Cells

(2008) Xing-gang Mao et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Chemoresistance in gliomas

(2008) Chen Lu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE