Rescue of fragile X syndrome phenotypes in Fmr1KO mice by a BKCa channel opener molecule

Reversal of activity-mediated spine dynamics and learning impairment in a mouse model of Fragile X syndrome

(2014) Bernadett Boda et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Astroglial FMRP-dependent translational down-regulation of mGluR5 underlies glutamate transporter GLT1 dysregulation in the fragile X mouse

(2013) Haruki Higashimori et al.   HUMAN MOLECULAR GENETICS

FMRP Regulates Neurotransmitter Release and Synaptic Information Transmission by Modulating Action Potential Duration via BK Channels

(2013) Pan-Yue Deng et al.   NEURON

Mice with Deficient BK Channel Function Show Impaired Prepulse Inhibition and Spatial Learning, but Normal Working and Spatial Reference Memory

(2013) Marei Typlt et al.   PLoS One

Fragile X syndrome: mechanistic insights and therapeutic avenues regarding the role of potassium channels

(2012) Hye Young Lee et al.   CURRENT OPINION IN NEUROBIOLOGY

Longitudinalin vivodevelopmental changes of metabolites in the hippocampus ofFmr1knockout mice

(2012) Da Shi et al.   JOURNAL OF NEUROCHEMISTRY

The Therapeutic effect of Memantine through the Stimulation of Synapse Formation and Dendritic Spine Maturation in Autism and Fragile X Syndrome

(2012) Hongen Wei et al.   PLoS One

Excessive Astrocyte-Derived Neurotrophin-3 Contributes to the Abnormal Neuronal Dendritic Development in a Mouse Model of Fragile X Syndrome

(2012) Qi Yang et al.   PLoS Genetics

FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism

(2011) Jennifer C. Darnell et al.   CELL

Potential role of KCNQ/M-channels in regulating neuronal differentiation in mouse hippocampal and embryonic stem cell-derived neuronal cultures

(2011) Xin Zhou et al.   EXPERIMENTAL NEUROLOGY

A metabolomic and systems biology perspective on the brain of the Fragile X syndrome mouse model

(2011) L. Davidovic et al.   GENOME RESEARCH

Subchronic Administration and Combination Metabotropic Glutamate and GABAB Receptor Drug Therapy in Fragile X Syndrome

(2011) L. K. K. Pacey et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Therapeutic Strategies in Fragile X Syndrome: Dysregulated mGluR Signaling and Beyond

(2011) Christina Gross et al.   NEUROPSYCHOPHARMACOLOGY

Effects of chronic immobilization stress on anxiety-like behavior and basolateral amygdala morphology in Fmr1 knockout mice

(2011) M. Qin et al.   NEUROSCIENCE

Genetic-Background Modulation of Core and Variable Autistic-Like Symptoms in Fmr1 Knock-Out Mice

(2011) Susanna Pietropaolo et al.   PLoS One

Evidence of reactive astrocytes but not peripheral immune system activation in a mouse model of Fragile X syndrome

(2010) Christopher J. Yuskaitis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Developmental characteristics of dendritic spines in the dentate gyrus of Fmr1 knockout mice

(2010) Aaron W. Grossman et al.   BRAIN RESEARCH

Astrocytes Prevent Abnormal Neuronal Development in the Fragile X Mouse

(2010) S. Jacobs et al.   JOURNAL OF NEUROSCIENCE

GSK3 Influences Social Preference and Anxiety-Related Behaviors during Social Interaction in a Mouse Model of Fragile X Syndrome and Autism

(2010) Marjelo A. Mines et al.   PLoS One

Lithium ameliorates altered glycogen synthase kinase-3 and behavior in a mouse model of Fragile X syndrome

(2009) Christopher J. Yuskaitis et al.   BIOCHEMICAL PHARMACOLOGY

Dissociation of social and nonsocial anxiety in a mouse model of fragile X syndrome

(2009) Zhong-Hua Liu et al.   NEUROSCIENCE LETTERS

MRI Characterization of Structural Mouse Brain Changes in Response to Chronic Exposure to the Glufosinate Ammonium Herbicide

(2009) Sandra Meme et al.   TOXICOLOGICAL SCIENCES

Evidence for social anxiety and impaired social cognition in a mouse model of fragile X syndrome.

(2008) Caitlyn H. McNaughton et al.   BEHAVIORAL NEUROSCIENCE

BK Channel Modulators: A Comprehensive Overview

(2008) Antonio Nardi et al.   CURRENT MEDICINAL CHEMISTRY

Social approach in genetically engineered mouse lines relevant to autism

(2008) S. S. Moy et al.   GENES BRAIN AND BEHAVIOR

Modest alterations in patterns of motor neuron dendrite morphology in the Fmr1 knockout mouse model for fragile X

(2008) Christina C. Thomas et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice

(2008) Femke M.S. de Vrij et al.   NEUROBIOLOGY OF DISEASE

Dysregulation of large-conductance Ca2+-activated K+ channel expression in nonsyndromal mental retardation due to a cereblon p.R419X mutation

(2008) Joseph J. Higgins et al.   NEUROGENETICS

Advances in the Treatment of Fragile X Syndrome

(2008) R. J. Hagerman et al.   PEDIATRICS

Quantitative proteomic analysis of primary neurons reveals diverse changes in synaptic protein content in fmr1 knockout mice

(2008) L. Liao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA