Targeting CGRP via receptor antagonism and antibody neutralisation in two distinct rodent models of migraine-like pain

Effect of a calcitonin gene-related peptide-binding L-RNA aptamer on neuronal activity in the rat spinal trigeminal nucleus

(2018) Michael J. M. Fischer et al.   JOURNAL OF HEADACHE AND PAIN

Chronic and intermittent administration of systemic nitroglycerin in the rat induces an increase in the gene expression of CGRP in central areas: potential contribution to pain processing

(2018) Rosaria Greco et al.   JOURNAL OF HEADACHE AND PAIN

CGRP as the target of new migraine therapies — successful translation from bench to clinic

(2018) Lars Edvinsson et al.   Nature Reviews Neurology

Peripherally Administered CGRP Induces Spontaneous Pain in Mice

(2018) Brandon J. Rea et al.   PAIN

A unique inbred rat strain with sustained cephalic hypersensitivity as a model of chronic migraine-like pain

(2018) Gordon Munro et al.   Scientific Reports

Nitroglycerine triggers triptan-responsive cranial allodynia and trigeminal neuronal hypersensitivity

(2018) Simon Akerman et al.   BRAIN

Delta opioid receptor agonists are effective for multiple types of headache disorders

(2018) Laura S. Moye et al.   NEUROPHARMACOLOGY

The role of calcitonin gene–related peptide in peripheral and central pain mechanisms including migraine

(2017) Smriti Iyengar et al.   PAIN

Pathophysiology of Migraine: A Disorder of Sensory Processing

(2017) Peter J. Goadsby et al.   PHYSIOLOGICAL REVIEWS

The effects of acute and preventive migraine therapies in a mouse model of chronic migraine

(2016) Alycia F Tipton et al.   CEPHALALGIA

Prevention of stress- or nitric oxide donor-induced medication overuse headache by a calcitonin gene-related peptide antibody in rodents

(2016) Caroline Machado Kopruszinski et al.   CEPHALALGIA

Ensuring transparency and minimization of methodologic bias in preclinical pain research

(2016) Nick A. Andrews et al.   PAIN

Calcitonin Gene-Related Peptide (CGRP): A New Target for Migraine

(2015) Andrew F. Russo   Annual Review of Pharmacology and Toxicology

Calcitonin gene-related peptide and migraine

(2015) Nazia Karsan et al.   CURRENT OPINION IN NEUROLOGY

Migraine: Multiple Processes, Complex Pathophysiology

(2015) R. Burstein et al.   JOURNAL OF NEUROSCIENCE

Update on Animal Models of Migraine

(2014) Marcela Romero-Reyes et al.   Current Pain and Headache Reports

Effects of CGRP receptor antagonism in nitroglycerin-induced hyperalgesia

(2013) R Greco et al.   CEPHALALGIA

Characterization of a novel model of chronic migraine

(2013) Amynah A. Pradhan et al.   PAIN

Pathophysiology of migraine

(2012) PeterJ Goadsby   Annals of Indian Academy of Neurology

St. John's wort relieves pain in an animal model of migraine

(2012) N. Galeotti et al.   EUROPEAN JOURNAL OF PAIN

Spontaneous Trigeminal Allodynia in Rats: A Model of Primary Headache

(2012) Michael L. Oshinsky et al.   HEADACHE

Differential effects of calcitonin gene-related peptide receptor blockade by olcegepant on mechanical allodynia induced by ligation of the infraorbital nerve vs the sciatic nerve in the rat

(2012) Benoît Michot et al.   PAIN

A naturalistic glyceryl trinitrate infusion migraine model in the rat

(2011) Roshni Ramachandran et al.   CEPHALALGIA

Possible site of action of CGRP antagonists in migraine

(2011) Peer Tfelt-Hansen et al.   CEPHALALGIA

Calcitonin gene-related peptide receptor antagonist olcegepant acts in the spinal trigeminal nucleus

(2009) Marie-Luise Sixt et al.   BRAIN

Delayed Migraine-Like Headache in Healthy Volunteers After a Combination of Acetazolamide and Glyceryl Trinitrate

(2009) D Daugaard et al.   CEPHALALGIA

Nitroglycerin provocation in normal subjects is not a useful human migraine model?

(2009) JF Tvedskov et al.   CEPHALALGIA

Calcitonin gene-related peptide (CGRP) levels during glyceryl trinitrate (GTN)-induced headache in healthy volunteers

(2009) C Kruuse et al.   CEPHALALGIA

Sumatriptan alleviates nitroglycerin-induced mechanical and thermal allodynia in mice

(2009) EA Bates et al.   CEPHALALGIA

Animal models of pain: progress and challenges

(2009) Jeffrey S. Mogil   NATURE REVIEWS NEUROSCIENCE