FNDC5 alleviates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via activating AKT
出版年份 2019 全文链接
标题
FNDC5 alleviates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via activating AKT
作者
关键词
-
出版物
CELL DEATH AND DIFFERENTIATION
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-06-17
DOI
10.1038/s41418-019-0372-z
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Humanin Analogue (HNG) Enhances the Protective Effect of Dexrazoxane against Doxorubicin-induced Cardiotoxicity
- (2018) YanHe Lue et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- T-bet deficiency attenuates cardiac remodelling in rats
- (2018) Zhen-Guo Ma et al. BASIC RESEARCH IN CARDIOLOGY
- A77 1726 (leflunomide) blocks and reverses cardiac hypertrophy and fibrosis in mice
- (2018) Zhen-Guo Ma et al. CLINICAL SCIENCE
- Irisin Protects Heart Against Ischemia-Reperfusion Injury Through a SOD2-Dependent Mitochondria Mechanism
- (2018) Zhen Wang et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Fndc5 knockdown induced suppression of mitochondrial integrity and significantly decreased cardiac differentiation of mouse embryonic stem cells
- (2018) Shima Nazem et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Fibronectin type III domain containing 5 attenuates NLRP3 inflammasome activation and phenotypic transformation of adventitial fibroblasts in spontaneously hypertensive rats
- (2018) Li Ling et al. JOURNAL OF HYPERTENSION
- CTRP3 protected against doxorubicin-induced cardiac dysfunction, inflammation and cell death via activation of Sirt1
- (2018) Yu-Pei Yuan et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Rosmarinic acid attenuates cardiac fibrosis following long-term pressure overload via AMPKα/Smad3 signaling
- (2018) Xin Zhang et al. Cell Death & Disease
- Sulforaphane prevents angiotensin II-induced cardiomyopathy by activation of Nrf2 via stimulating the Akt/GSK-3ß/Fyn pathway
- (2018) Ying Xin et al. Redox Biology
- MicroRNA-140-5p aggravates doxorubicin-induced cardiotoxicity by promoting myocardial oxidative stress via targeting Nrf2 and Sirt2
- (2018) Lisha Zhao et al. Redox Biology
- Irisin alleviates pressure overload-induced cardiac hypertrophy by inducing protective autophagy via mTOR-independent activation of the AMPK-ULK1 pathway
- (2018) Ru-Li Li et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Irisin plays a pivotal role to protect the heart against ischemia and reperfusion injury
- (2017) Hao Wang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Physiology and role of irisin in glucose homeostasis
- (2017) Nikolaos Perakakis et al. Nature Reviews Endocrinology
- Irisin protects mitochondria function during pulmonary ischemia/reperfusion injury
- (2017) Ken Chen et al. Science Translational Medicine
- Restricting the induction of NGF in ovarian stroma engenders selective follicular activation through the mTOR signaling pathway
- (2017) Yuanlin He et al. Cell Death & Disease
- Piperine Attenuates Pathological Cardiac Fibrosis Via PPAR-γ/AKT Pathways
- (2017) Zhen-Guo Ma et al. EBioMedicine
- Protection against cardiac hypertrophy by geniposide involves the GLP-1 receptor / AMPKα signalling pathway
- (2016) Zhen-Guo Ma et al. BRITISH JOURNAL OF PHARMACOLOGY
- FNDC5 Alleviates Hepatosteatosis by Restoring AMPK/mTOR-Mediated Autophagy, Fatty Acid Oxidation, and Lipogenesis in Mice
- (2016) Tong-Yan Liu et al. DIABETES
- Asiatic Acid Protects against Cardiac Hypertrophy through Activating AMPKα Signalling Pathway
- (2016) Zhen-Guo Ma et al. International Journal of Biological Sciences
- Irisin Lowers Blood Pressure by Improvement of Endothelial Dysfunction via AMPK‐Akt‐eNOS‐NO Pathway in the Spontaneously Hypertensive Rat
- (2016) Jinjuan Fu et al. Journal of the American Heart Association
- Irisin Inhibits Hepatic Cholesterol Synthesis via AMPK-SREBP2 Signaling
- (2016) Hong Tang et al. EBioMedicine
- Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes
- (2015) T.-Y. Liu et al. CLINICAL SCIENCE
- Cardiac differentiation of mouse embryonic stem cells is influenced by a PPAR γ/PGC-1α—FNDC5 pathway during the stage of cardiac precursor cell formation
- (2015) Faezeh Ghazvini Zadegan et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Andrographolide inhibits TNFα-induced ICAM-1 expression via suppression of NADPH oxidase activation and induction of HO-1 and GCLM expression through the PI3K/Akt/Nrf2 and PI3K/Akt/AP-1 pathways in human endothelial cells
- (2014) Chia-Yang Lu et al. BIOCHEMICAL PHARMACOLOGY
- Induced expression of Fndc5 significantly increased cardiomyocyte differentiation rate of mouse embryonic stem cells
- (2014) Farzaneh Rabiee et al. GENE
- Effects of the exercise-inducible myokine irisin on malignant and non-malignant breast epithelial cell behaviorin vitro
- (2014) Nicholas P. Gannon et al. INTERNATIONAL JOURNAL OF CANCER
- Heme Oxygenase-1 Protects against Neutrophil-Mediated Intestinal Damage by Down-Regulation of Neutrophil p47phox and p67phox Activity and O2- Production in a Two-Hit Model of Alcohol Intoxication and Burn Injury
- (2014) X. Li et al. JOURNAL OF IMMUNOLOGY
- Irisin: A potentially candidate marker for myocardial infarction
- (2014) Tuncay Kuloglu et al. PEPTIDES
- Role of Nrf2 in Oxidative Stress and Toxicity
- (2013) Qiang Ma Annual Review of Pharmacology and Toxicology
- Mechanistic Target of Rapamycin Complex 2 Protects the Heart From Ischemic Damage
- (2013) Mirko Völkers et al. CIRCULATION
- Manipulation of Cardiac Phosphatidylinositol 3-Kinase (PI3K)/Akt Signaling by Apoptosis Regulator through Modulating IAP Expression (ARIA) Regulates Cardiomyocyte Death during Doxorubicin-induced Cardiomyopathy
- (2013) Youhei Kitamura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies
- (2012) Yanti Octavia et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
- (2012) Pontus Boström et al. NATURE
- Identification of the molecular basis of doxorubicin-induced cardiotoxicity
- (2012) Sui Zhang et al. NATURE MEDICINE
- Reactive oxygen species, cellular redox systems, and apoptosis
- (2010) Magdalena L. Circu et al. FREE RADICAL BIOLOGY AND MEDICINE
- Bilirubin and biliverdin protect rodents against diabetic nephropathy by downregulating NAD(P)H oxidase
- (2010) Masakazu Fujii et al. KIDNEY INTERNATIONAL
- CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes
- (2009) Partha Mukhopadhyay et al. CARDIOVASCULAR RESEARCH
- Doxorubicin: The Good, the Bad and the Ugly Effect
- (2009) Cristina Carvalho et al. CURRENT MEDICINAL CHEMISTRY
- Acute Doxorubicin Cardiotoxicity Is Associated With p53-Induced Inhibition of the Mammalian Target of Rapamycin Pathway
- (2008) Wuqiang Zhu et al. CIRCULATION
- Heat Shock Protein 20 Interacting With Phosphorylated Akt Reduces Doxorubicin-Triggered Oxidative Stress and Cardiotoxicity
- (2008) Guo-Chang Fan et al. CIRCULATION RESEARCH
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started