Inhibitory Effects of the Two Novel TSPO Ligands 2-Cl-MGV-1 and MGV-1 on LPS-induced Microglial Activation

Lipoxin A4 Regulates Lipopolysaccharide-Induced BV2 Microglial Activation and Differentiation via the Notch Signaling Pathway

(2019) Jun Wu et al.   Frontiers in Cellular Neuroscience

Translocator protein ligand protects against neurodegeneration in the MPTP mouse model of Parkinsonism

(2019) Jing Gong et al.   JOURNAL OF NEUROSCIENCE

The TSPO Ligands 2-Cl-MGV-1, MGV-1, and PK11195 Differentially Suppress the Inflammatory Response of BV-2 Microglial Cell to LPS

(2019) Maya Azrad et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Mycobacterial Adjuvant Analogue TDB Attenuates Neuroinflammation via Mincle-Independent PLC-γ1/PKC/ERK Signaling and Microglial Polarization

(2018) Mahendravarman Mohanraj et al.   MOLECULAR NEUROBIOLOGY

Microglial control of astrocytes in response to microbial metabolites

(2018) Veit Rothhammer et al.   NATURE

Inhibitory Effects of Betulinic Acid on LPS-Induced Neuroinflammation Involve M2 Microglial Polarization via CaMKKβ-Dependent AMPK Activation

(2018) Chuwen Li et al.   Frontiers in Molecular Neuroscience

Transcriptional and functional diversity of human macrophage repolarization

(2018) Sina A. Gharib et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Classical and Novel TSPO Ligands for the Mitochondrial TSPO Can Modulate Nuclear Gene Expression: Implications for Mitochondrial Retrograde Signaling

(2017) Nasra Yasin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Emerging Role of Zinc in the Pathogenesis of Multiple Sclerosis

(2017) Bo Choi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Peli1 Contributions in Microglial Activation, Neuroinflammatory Responses and Neurological Deficits Following Experimental Subarachnoid Hemorrhage

(2017) Xue-Ping Huang et al.   Frontiers in Molecular Neuroscience

The macrophage marker translocator protein (TSPO) is down-regulated on pro-inflammatory ‘M1’ human macrophages

(2017) Nehal Narayan et al.   PLoS One

Translocator Protein 18 kDa (TSPO): An Old Protein with New Functions?

(2016) Fei Li et al.   BIOCHEMISTRY

IL-10 secreted by M2 macrophage promoted tumorigenesis through interaction with JAK2 in glioma

(2016) Ling Qi et al.   Oncotarget

The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation

(2016) Anja Henn   ALTEX-Alternatives to Animal Experimentation

Melanoma-initiating cells exploit M2 macrophage TGFβ and arginase pathway for survival and proliferation

(2015) Muly Tham et al.   Oncotarget

The Marine Fungal Metabolite, AD0157, Inhibits Angiogenesis by Targeting the Akt Signaling Pathway

(2014) Melissa García-Caballero et al.   Marine Drugs

Microglial and macrophage polarization—new prospects for brain repair

(2014) Xiaoming Hu et al.   Nature Reviews Neurology

Neuroinflammation: The role and consequences

(2013) Monty Lyman et al.   NEUROSCIENCE RESEARCH

Microglia Activation as a Biomarker for Traumatic Brain Injury

(2013) Diana G. Hernandez-Ontiveros et al.   Frontiers in Neurology

Adoptive transfer of IL-4Rα+ macrophages is sufficient to enhance eosinophilic inflammation in a mouse model of allergic lung inflammation

(2012) Andrew Q Ford et al.   BMC IMMUNOLOGY

TSPO-specific ligand Vinpocetine exerts a neuroprotective effect by suppressing microglial inflammation

(2012) Yan-Yin Zhao et al.   Neuron Glia Biology

An ADIOL-ERβ-CtBP Transrepression Pathway Negatively Regulates Microglia-Mediated Inflammation

(2011) Kaoru Saijo et al.   CELL

The Mechanism of Action of Interferon-β in Relapsing Multiple Sclerosis

(2011) Bernd C. Kieseier   CNS DRUGS

Repertoire of microglial and macrophage responses after spinal cord injury

(2011) Samuel David et al.   NATURE REVIEWS NEUROSCIENCE

Abrogated Inflammatory Response Promotes Neurogenesis in a Murine Model of Japanese Encephalitis

(2011) Sulagna Das et al.   PLoS One

Serum amyloid P attenuates M2 macrophage activation and protects against fungal spore–induced allergic airway disease

(2010) Ana Paula Moreira et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Krüppel-like factor 4, a novel transcription factor regulates microglial activation and subsequent neuroinflammation

(2010) Deepak K Kaushik et al.   Journal of Neuroinflammation

Regulation of translocator protein 18kDa (TSPO) expression in health and disease states☆

(2010) Amani Batarseh et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Macrophages

(2009) Barbro N. Melgert et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Heterogeneity of Microglial Activation in the Innate Immune Response in the Brain

(2009) Carol A. Colton   Journal of Neuroimmune Pharmacology

Src kinase participates in LPS-induced activation of NADPH oxidase

(2009) Jennifer Check et al.   MOLECULAR IMMUNOLOGY

Glatiramer acetate increases IL-1 receptor antagonist but decreases T cell-induced IL-1  in human monocytes and multiple sclerosis

(2009) D. Burger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The distinct roles of cyclooxygenase-1 and -2 in neuroinflammation: implications for translational research

(2009) Sang-Ho Choi et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

VDAC activation by the 18 kDa translocator protein (TSPO), implications for apoptosis

(2008) Leo Veenman et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

From endoplasmic-reticulum stress to the inflammatory response

(2008) Kezhong Zhang et al.   NATURE