BRICHOS Domains Efficiently Delay Fibrillation of Amyloid β-Peptide

High-resolution structure of a BRICHOS domain and its implications for anti-amyloid chaperone activity on lung surfactant protein C

(2012) H. Willander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

APP heterozygosity averts memory deficit in knockin mice expressing the Danish dementia BRI2 mutant

(2011) Robert Tamayev et al.   EMBO JOURNAL

BRICHOS domain associated with lung fibrosis, dementia and cancer - a chaperone that prevents amyloid fibril formation?

(2011) Hanna Willander et al.   FEBS Journal

The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β1−40 peptide

(2011) Priyanka Narayan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Danish dementia mice suggest that loss of function and not the amyloid cascade causes synaptic plasticity and memory deficits

(2010) R. Tamayev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequestration of the Aβ Peptide Prevents Toxicity and Promotes Degradation In Vivo

(2010) Leila M. Luheshi et al.   PLOS BIOLOGY

Amyloid β-Protein Aggregation Produces Highly Reproducible Kinetic Data and Occurs by a Two-Phase Process

(2009) Erik Hellstrand et al.   ACS Chemical Neuroscience

The extracellular domain of Bri2 (ITM2B) binds the ABri peptide (1–23) and amyloid β-peptide (Aβ1–40): Implications for Bri2 effects on processing of amyloid precursor protein and Aβ aggregation

(2009) Siwei Peng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structural integrity of β-sheet assembly

(2009) Karen E. Marshall et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Anti-Amyloid Activity of the C-Terminal Domain of proSP-C against Amyloid β-Peptide and Medin†

(2009) Charlotte Nerelius et al.   BIOCHEMISTRY

C-terminal, endoplasmic reticulum-lumenal domain of prosurfactant protein C - structural features and membrane interactions

(2009) Cristina Casals et al.   FEBS Journal

A facile method for expression and purification of the Alzheimer’s disease-associated amyloid β-peptide

(2009) Dominic M. Walsh et al.   FEBS Journal

Structure-activity relationship of amyloid fibrils

(2009) Samir K. Maji et al.   FEBS LETTERS

The role of molecular chaperones in human misfolding diseases

(2009) Sarah A. Broadley et al.   FEBS LETTERS

Preventing Amyloid Formation by Catching Unfolded Transmembrane Segments

(2009) H. Johansson et al.   JOURNAL OF MOLECULAR BIOLOGY

Aβ43 is more frequent than Aβ40 in amyloid plaque cores from Alzheimer disease brains

(2009) Hedvig Welander et al.   JOURNAL OF NEUROCHEMISTRY

Inhibition of IAPP and IAPP(20−29)Fibrillation by Polymeric Nanoparticles

(2009) C. Cabaleiro-Lago et al.   LANGMUIR

The Brichos domain of prosurfactant protein C can hold and fold a transmembrane segment

(2009) Hanna Johansson et al.   PROTEIN SCIENCE

Mutations linked to interstitial lung disease can abrogate anti-amyloid function of prosurfactant protein C

(2008) Charlotte Nerelius et al.   BIOCHEMICAL JOURNAL

Protease Activation of α2-Macroglobulin Modulates a Chaperone-like Action with Broad Specificity

(2008) Katie French et al.   BIOCHEMISTRY

Amyloid β -Protein Assembly as a Therapeutic Target of Alzheimers Disease

(2008) Ghiam Yamin et al.   CURRENT PHARMACEUTICAL DESIGN

α2-Macroglobulin and Haptoglobin Suppress Amyloid Formation by Interacting with Prefibrillar Protein Species

(2008) Justin J. Yerbury et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hsp104 Targets Multiple Intermediates on the Amyloid Pathway and Suppresses the Seeding Capacity of Aβ Fibrils and Protofibrils

(2008) Muriel Arimon et al.   JOURNAL OF MOLECULAR BIOLOGY

BRI2 (ITM2b) Inhibits A  Deposition In Vivo

(2008) J. Kim et al.   JOURNAL OF NEUROSCIENCE

Inhibition of Amyloid β Protein Fibrillation by Polymeric Nanoparticles

(2008) Celia Cabaleiro-Lago et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stabilization of a β-hairpin in monomeric Alzheimer's amyloid-β peptide inhibits amyloid formation

(2008) Wolfgang Hoyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chaperone-dependent amyloid assembly protects cells from prion toxicity

(2008) P. M. Douglas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Potential roles of abundant extracellular chaperones in the control of amyloid formation and toxicity

(2007) Mark R. Wilson et al.   Molecular BioSystems