Organs to Cells and Cells to Organoids: The Evolution of in vitro Central Nervous System Modelling
出版年份 2019 全文链接
标题
Organs to Cells and Cells to Organoids: The Evolution of in vitro Central Nervous System Modelling
作者
关键词
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出版物
Frontiers in Cellular Neuroscience
Volume 13, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2019-04-09
DOI
10.3389/fncel.2019.00129
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Development and Characterization of Human Cerebral Organoids
- (2018) Abraam M. Yakoub et al. CELL TRANSPLANTATION
- Assessment of AAV Vector Tropisms for Mouse and Human Pluripotent Stem Cell–Derived RPE and Photoreceptor Cells
- (2018) Anai Gonzalez-Cordero et al. HUMAN GENE THERAPY
- Human neural stem cells dispersed in artificial ECM form cerebral organoids when grafted in vivo
- (2018) Reem Basuodan et al. JOURNAL OF ANATOMY
- Cerebral organoids derived from Sandhoff disease-induced pluripotent stem cells exhibit impaired neurodifferentiation
- (2018) Maria L. Allende et al. JOURNAL OF LIPID RESEARCH
- Ethical (and epistemological) issues regarding consciousness in cerebral organoids
- (2018) Joshua Shepherd JOURNAL OF MEDICAL ETHICS
- Cerebral organoids: ethical issues and consciousness assessment
- (2018) Andrea Lavazza et al. JOURNAL OF MEDICAL ETHICS
- Human brain organoid-on-a-chip to model prenatal nicotine exposure
- (2018) Yaqing Wang et al. LAB ON A CHIP
- An in vivo model of functional and vascularized human brain organoids
- (2018) Abed AlFatah Mansour et al. NATURE BIOTECHNOLOGY
- A 3D human triculture system modeling neurodegeneration and neuroinflammation in Alzheimer’s disease
- (2018) Joseph Park et al. NATURE NEUROSCIENCE
- Generation of human vascularized brain organoids
- (2018) Missy T. Pham et al. NEUROREPORT
- Six-month cultured cerebral organoids from human ES cells contain matured neural cells
- (2018) Takeshi K. Matsui et al. NEUROSCIENCE LETTERS
- Neanderthal brain organoids come to life
- (2018) Jon Cohen SCIENCE
- Generation of Neural Organoids from Human Embryonic Stem Cells Using the Rotary Cell Culture System: Effects of Microgravity on Neural Progenitor Cell Fate
- (2018) Cristiana Mattei et al. STEM CELLS AND DEVELOPMENT
- A scale out approach towards neural induction of human induced pluripotent stem cells for neurodevelopmental toxicity studies
- (2018) Cláudia C. Miranda et al. TOXICOLOGY LETTERS
- Human Cortex Spheroid with a Functional Blood Brain Barrier for High-Throughput Neurotoxicity Screening and Disease Modeling
- (2018) Goodwell Nzou et al. Scientific Reports
- Translational potential of human brain organoids
- (2018) Alfred X. Sun et al. Annals of Clinical and Translational Neurology
- Stem-cell culture moves to the third dimension
- (2018) C. Y. Tachibana NATURE
- Animal models of neurodegenerative diseases
- (2018) Ted M. Dawson et al. NATURE NEUROSCIENCE
- A Three-Dimensional Organoid Culture Model to Assess the Influence of Chemicals on Morphogenetic Fusion
- (2018) David G Belair et al. TOXICOLOGICAL SCIENCES
- The development of an in vitro cerebral organoid model for investigating the pathomolecular mechanisms associated with the central nervous system involvement in Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE)
- (2018) Dario Pacitti et al. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
- Reactive Astrocytes: Production, Function, and Therapeutic Potential
- (2017) Shane A. Liddelow et al. IMMUNITY
- Probing impaired neurogenesis in human brain organoids exposed to alcohol
- (2017) Yujuan Zhu et al. Integrative Biology
- Induced Pluripotent Stem Cells Derived from a CLN5 Patient Manifest Phenotypic Characteristics of Neuronal Ceroid Lipofuscinoses
- (2017) Kristiina Uusi-Rauva et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Considering aspects of the 3Rs principles within experimental animal biology
- (2017) Lynne U. Sneddon et al. JOURNAL OF EXPERIMENTAL BIOLOGY
- In situ generation of human brain organoids on a micropillar array
- (2017) Yujuan Zhu et al. LAB ON A CHIP
- MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling
- (2017) N Mellios et al. MOLECULAR PSYCHIATRY
- Assembly of functionally integrated human forebrain spheroids
- (2017) Fikri Birey et al. NATURE
- Cell diversity and network dynamics in photosensitive human brain organoids
- (2017) Giorgia Quadrato et al. NATURE
- Guided self-organization and cortical plate formation in human brain organoids
- (2017) Madeline A Lancaster et al. NATURE BIOTECHNOLOGY
- Generation of pure GABAergic neurons by transcription factor programming
- (2017) Nan Yang et al. NATURE METHODS
- The use of brain organoids to investigate neural development and disease
- (2017) Elizabeth Di Lullo et al. NATURE REVIEWS NEUROSCIENCE
- Using induced pluripotent stem cells derived neurons to model brain diseases
- (2017) CindyE McKinney Neural Regeneration Research
- Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells
- (2017) Steven A. Sloan et al. NEURON
- DISC1 Regulates Neurogenesis via Modulating Kinetochore Attachment of Ndel1/Nde1 during Mitosis
- (2017) Fei Ye et al. NEURON
- Derivation of Functional Human Astrocytes from Cerebral Organoids
- (2017) Rômulo Sperduto Dezonne et al. Scientific Reports
- An Organoid-Based Model of Cortical Development Identifies Non-Cell-Autonomous Defects in Wnt Signaling Contributing to Miller-Dieker Syndrome
- (2017) Vira Iefremova et al. Cell Reports
- Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B
- (2017) Yu Zhang et al. Stem Cell Reports
- Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells
- (2017) Anna S. Monzel et al. Stem Cell Reports
- Genetic Correction of SOD1 Mutant iPSCs Reveals ERK and JNK Activated AP1 as a Driver of Neurodegeneration in Amyotrophic Lateral Sclerosis
- (2017) Akshay Bhinge et al. Stem Cell Reports
- GSK3ß-dependent dysregulation of neurodevelopment in SPG11-patient induced pluripotent stem cell model
- (2016) Himanshu K. Mishra et al. ANNALS OF NEUROLOGY
- Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure
- (2016) Xuyu Qian et al. CELL
- Modeling Development and Disease with Organoids
- (2016) Hans Clevers CELL
- Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons
- (2016) Junghyun Jo et al. Cell Stem Cell
- Zika Virus Depletes Neural Progenitors in Human Cerebral Organoids through Activation of the Innate Immune Receptor TLR3
- (2016) Jason Dang et al. Cell Stem Cell
- Stem Cell Models of Human Brain Development
- (2016) Iva Kelava et al. Cell Stem Cell
- Engineering Stem Cell Organoids
- (2016) Xiaolei Yin et al. Cell Stem Cell
- Dishing out mini-brains: Current progress and future prospects in brain organoid research
- (2016) Iva Kelava et al. DEVELOPMENTAL BIOLOGY
- Mislocalization of syntaxin-1 and impaired neurite growth observed in a human iPSC model forSTXBP1-related epileptic encephalopathy
- (2016) Satoshi Yamashita et al. EPILEPSIA
- Developments in 3D neural cell culture models: the future of neurotherapeutics testing?
- (2016) Kristin Robin Ko et al. Expert Review of Neurotherapeutics
- Cockayne syndrome-derived neurons display reduced synapse density and altered neural network synchrony
- (2016) Alexandre T. Vessoni et al. HUMAN MOLECULAR GENETICS
- The Brazilian Zika virus strain causes birth defects in experimental models
- (2016) Fernanda R. Cugola et al. NATURE
- Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system
- (2016) Michael J Workman et al. NATURE MEDICINE
- Pluripotent stem cells in disease modelling and drug discovery
- (2016) Yishai Avior et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cellular and molecular introduction to brain development
- (2016) Xiangning Jiang et al. NEUROBIOLOGY OF DISEASE
- CYP3A5 Mediates Effects of Cocaine on Human Neocorticogenesis: Studies using an In Vitro 3D Self-Organized hPSC Model with a Single Cortex-Like Unit
- (2016) Chun-Ting Lee et al. NEUROPSYCHOPHARMACOLOGY
- KCC2 rescues functional deficits in human neurons derived from patients with Rett syndrome
- (2016) Xin Tang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Zika virus impairs growth in human neurospheres and brain organoids
- (2016) P. P. Garcez et al. SCIENCE
- Spinal Muscular Atrophy Patient iPSC-Derived Motor Neurons Have Reduced Expression of Proteins Important in Neuronal Development
- (2016) Heidi R. Fuller et al. Frontiers in Cellular Neuroscience
- Astrocyte Differentiation of Human Pluripotent Stem Cells: New Tools for Neurological Disorder Research
- (2016) Abinaya Chandrasekaran et al. Frontiers in Cellular Neuroscience
- Unique membrane properties and enhanced signal processing in human neocortical neurons
- (2016) Guy Eyal et al. eLife
- Developments in 3D neural cell culture models: the future of neurotherapeutics testing?
- (2016) Kristin Robin Ko et al. Expert Review of Neurotherapeutics
- CRISPR/Cas9 facilitates investigation of neural circuit disease using human iPSCs: mechanism of epilepsy caused by an SCN1A loss-of-function mutation
- (2016) J Liu et al. Translational Psychiatry
- Utility of Induced Pluripotent Stem Cells for the Study and Treatment of Genetic Diseases: Focus on Childhood Neurological Disorders
- (2016) Serena Barral et al. Frontiers in Molecular Neuroscience
- Differentiation of the SH-SY5Y Human Neuroblastoma Cell Line
- (2016) Mackenzie M. Shipley et al. Jove-Journal of Visualized Experiments
- Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer’s Disease Phenotypes
- (2016) Waseem K. Raja et al. PLoS One
- Optimization of Matrigel-based culture for expansion of neural stem cells
- (2015) Seung-Won Lee et al. Animal Cells and Systems
- Spatial and temporal control of cell aggregation efficiently directs human pluripotent stem cells towards neural commitment
- (2015) Cláudia C. Miranda et al. Biotechnology Journal
- FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders
- (2015) Jessica Mariani et al. CELL
- Genome-wide RNA-Seq of Human Motor Neurons Implicates Selective ER Stress Activation in Spinal Muscular Atrophy
- (2015) Shi-Yan Ng et al. Cell Stem Cell
- Retinoic acid signaling and neuronal differentiation
- (2015) Amanda Janesick et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Dendritic and Axonal Architecture of Individual Pyramidal Neurons across Layers of Adult Human Neocortex
- (2015) Hemanth Mohan et al. CEREBRAL CORTEX
- Activin/Nodal signalling in stem cells
- (2015) S. Pauklin et al. DEVELOPMENT
- Abnormal mitochondrial transport and morphology as early pathological changes in human models of spinal muscular atrophy
- (2015) Chong-Chong Xu et al. Disease Models & Mechanisms
- Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients
- (2015) R. Fernandez-Santiago et al. EMBO Molecular Medicine
- SMN deficiency does not induce oxidative stress in SMA iPSC-derived astrocytes or motor neurons
- (2015) Teresa N. Patitucci et al. HUMAN MOLECULAR GENETICS
- Altered TFEB-mediated lysosomal biogenesis in Gaucher disease iPSC-derived neuronal cells
- (2015) Ola Awad et al. HUMAN MOLECULAR GENETICS
- Arylsulfatase A Overexpressing Human iPSC-derived Neural Cells Reduce CNS Sulfatide Storage in a Mouse Model of Metachromatic Leukodystrophy
- (2015) Jonas Doerr et al. MOLECULAR THERAPY
- Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture
- (2015) Anca M Paşca et al. NATURE METHODS
- MECP2e1 isoform mutation affects the form and function of neurons derived from Rett syndrome patient iPS cells
- (2015) Ugljesa Djuric et al. NEUROBIOLOGY OF DISEASE
- Human cerebral organoids recapitulate gene expression programs of fetal neocortex development
- (2015) J. Gray Camp et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human pluripotent stem cell-derived neural constructs for predicting neural toxicity
- (2015) Michael P. Schwartz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Three-Dimensional Neural Spheroid Culture: AnIn VitroModel for Cortical Studies
- (2015) Yu-Ting L. Dingle et al. TISSUE ENGINEERING PART C-METHODS
- Analysing human neural stem cell ontogeny by consecutive isolation of Notch active neural progenitors
- (2015) Reuven Edri et al. Nature Communications
- Generation of functional hippocampal neurons from self-organizing human embryonic stem cell-derived dorsomedial telencephalic tissue
- (2015) Hideya Sakaguchi et al. Nature Communications
- Spinal muscular atrophy phenotype is ameliorated in human motor neurons by SMN increase via different novel RNA therapeutic approaches
- (2015) Monica Nizzardo et al. Scientific Reports
- Decay in survival motor neuron and plastin 3 levels during differentiation of iPSC-derived human motor neurons
- (2015) María G Boza-Morán et al. Scientific Reports
- Spinal muscular atrophy patient-derived motor neurons exhibit hyperexcitability
- (2015) Huisheng Liu et al. Scientific Reports
- Poly-L-ornithine promotes preferred differentiation of neural stem/progenitor cells via ERK signalling pathway
- (2015) Hongfei Ge et al. Scientific Reports
- Reversion of FMR1 Methylation and Silencing by Editing the Triplet Repeats in Fragile X iPSC-Derived Neurons
- (2015) Chul-Yong Park et al. Cell Reports
- Self-Organization of Polarized Cerebellar Tissue in 3D Culture of Human Pluripotent Stem Cells
- (2015) Keiko Muguruma et al. Cell Reports
- Rescue of an In Vitro Neuron Phenotype Identified in Niemann-Pick Disease, Type C1 Induced Pluripotent Stem Cell-Derived Neurons by Modulating the WNT Pathway and Calcium Signaling
- (2015) Anastasia G. Efthymiou et al. Stem Cells Translational Medicine
- Spatial and temporal control of cell aggregation efficiently directs human pluripotent stem cells towards neural commitment
- (2015) Cláudia C. Miranda et al. Biotechnology Journal
- Molecular Mechanisms Regulating the Defects in Fragile X Syndrome Neurons Derived from Human Pluripotent Stem Cells
- (2015) Tomer Halevy et al. Stem Cell Reports
- Modeling the Early Phenotype at the Neuromuscular Junction of Spinal Muscular Atrophy Using Patient-Derived iPSCs
- (2015) Michiko Yoshida et al. Stem Cell Reports
- Properties of Neurons Derived from Induced Pluripotent Stem Cells of Gaucher Disease Type 2 Patient Fibroblasts: Potential Role in Neuropathology
- (2015) Ying Sun et al. PLoS One
- Functional Characterization of IPSC-Derived Brain Cells as a Model for X-Linked Adrenoleukodystrophy
- (2015) Mauhamad Baarine et al. PLoS One
- Generating Human Neurons In Vitro and Using Them to Understand Neuropsychiatric Disease
- (2014) Sergiu P. Paşca et al. Annual Review of Neuroscience
- Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons
- (2014) S. Havlicek et al. HUMAN MOLECULAR GENETICS
- Pharmacologic rescue of axon growth defects in a human iPSC model of hereditary spastic paraplegia SPG3A
- (2014) Peng-Peng Zhu et al. HUMAN MOLECULAR GENETICS
- Mutant astrocytes differentiated from Rett syndrome patients-specific iPSCs have adverse effects on wild-type neurons
- (2014) Emily Cunningham Williams et al. HUMAN MOLECULAR GENETICS
- The generation of induced pluripotent stem cells (iPSCs) from patients with infantile and late-onset types of Pompe disease and the effects of treatment with acid-α-glucosidase in Pompe's iPSCs
- (2014) Takashi Higuchi et al. MOLECULAR GENETICS AND METABOLISM
- Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons
- (2014) K Griesi-Oliveira et al. MOLECULAR PSYCHIATRY
- Generation of cerebral organoids from human pluripotent stem cells
- (2014) Madeline A Lancaster et al. Nature Protocols
- Astrocyte Reactivity and Reactive Astrogliosis: Costs and Benefits
- (2014) Milos Pekny et al. PHYSIOLOGICAL REVIEWS
- Sensory Neurons Do Not Induce Motor Neuron Loss in a Human Stem Cell Model of Spinal Muscular Atrophy
- (2014) Andrew J. Schwab et al. PLoS One
- Functional Characterization of Friedreich Ataxia iPS-Derived Neuronal Progenitors and Their Integration in the Adult Brain
- (2014) Matthew J. Bird et al. PLoS One
- Concise Review: Generation of Neurons From Somatic Cells of Healthy Individuals and Neurological Patients Through Induced Pluripotency or Direct Conversion
- (2014) Iván Velasco et al. STEM CELLS
- iPSC-Derived Forebrain Neurons from FXS Individuals Show Defects in Initial Neurite Outgrowth
- (2014) Matthew E. Doers et al. STEM CELLS AND DEVELOPMENT
- Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency
- (2014) L Carlessi et al. Cell Death & Disease
- Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome
- (2014) Yuan Tian et al. Genome Medicine
- Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons
- (2013) Sandra Almeida et al. ACTA NEUROPATHOLOGICA
- Dravet syndrome patient-derived neurons suggest a novel epilepsy mechanism
- (2013) Yu Liu et al. ANNALS OF NEUROLOGY
- The Pivotal Role of Vascularization in Tissue Engineering
- (2013) François A. Auger et al. Annual Review of Biomedical Engineering
- Single-cell analysis of embryoid body heterogeneity using microfluidic trapping array
- (2013) Jenna L. Wilson et al. BIOMEDICAL MICRODEVICES
- A Small Molecule Screen in Stem-Cell-Derived Motor Neurons Identifies a Kinase Inhibitor as a Candidate Therapeutic for ALS
- (2013) Yin M. Yang et al. Cell Stem Cell
- Bioactive 3D cell culture system minimizes cellular stress and maintains thein vivo-like morphological complexity of astroglial cells
- (2013) Till B. Puschmann et al. GLIA
- Spinal muscular atrophy astrocytes exhibit abnormal calcium regulation and reduced growth factor production
- (2013) Jered V. McGivern et al. GLIA
- Modeling Dravet syndrome using induced pluripotent stem cells (iPSCs) and directly converted neurons
- (2013) Jiao Jiao et al. HUMAN MOLECULAR GENETICS
- Human iPSC models of neuronal ceroid lipofuscinosis capture distinct effects of TPP1 and CLN3 mutations on the endocytic pathway
- (2013) Xenia Lojewski et al. HUMAN MOLECULAR GENETICS
- HB-EGF affects astrocyte morphology, proliferation, differentiation, and the expression of intermediate filament proteins
- (2013) Till B. Puschmann et al. JOURNAL OF NEUROCHEMISTRY
- Microglia Regulate the Number of Neural Precursor Cells in the Developing Cerebral Cortex
- (2013) C. L. Cunningham et al. JOURNAL OF NEUROSCIENCE
- SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients
- (2013) Aleksandr Shcheglovitov et al. NATURE
- Cerebral organoids model human brain development and microcephaly
- (2013) Madeline A. Lancaster et al. NATURE
- Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells
- (2013) Yingsha Zhang et al. NEURON
- Niemann-Pick type C1 patient-specific induced pluripotent stem cells display disease specific hallmarks
- (2013) Michaela Trilck et al. Orphanet Journal of Rare Diseases
- Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy
- (2013) A. Serio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex
- (2013) T. Kadoshima et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Loss of Spastin Function Results in Disease-Specific Axonal Defects in Human Pluripotent Stem Cell-Based Models of Hereditary Spastic Paraplegia
- (2013) Kyle R. Denton et al. STEM CELLS
- Induced Pluripotent Stem Cells from Friedreich Ataxia Patients Fail to Upregulate Frataxin During In Vitro Differentiation to Peripheral Sensory Neurons
- (2013) Andreas Eigentler et al. STEM CELLS AND DEVELOPMENT
- A human Dravet syndrome model from patient induced pluripotent stem cells
- (2013) Norimichi Higurashi et al. Molecular Brain
- Induced Pluripotent Stem Cells from Patients with Huntington's Disease Show CAG-Repeat-Expansion-Associated Phenotypes
- (2012) The HD iPSC Consortium Cell Stem Cell
- Direct Reprogramming of Mouse and Human Fibroblasts into Multipotent Neural Stem Cells with a Single Factor
- (2012) Karen L. Ring et al. Cell Stem Cell
- Spindle orientation in mammalian cerebral cortical development
- (2012) Madeline A Lancaster et al. CURRENT OPINION IN NEUROBIOLOGY
- Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich's ataxia
- (2012) A. Hick et al. Disease Models & Mechanisms
- Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease
- (2012) Adriana Sánchez-Danés et al. EMBO Molecular Medicine
- Neuronopathic Gaucher's disease: induced pluripotent stem cells for disease modelling and testing chaperone activity of small compounds
- (2012) Gustavo Tiscornia et al. HUMAN MOLECULAR GENETICS
- Brain slice on a chip: opportunities and challenges of applying microfluidic technology to intact tissues
- (2012) Yu Huang et al. LAB ON A CHIP
- Large-scale screening using familial dysautonomia induced pluripotent stem cells identifies compounds that rescue IKBKAP expression
- (2012) Gabsang Lee et al. NATURE BIOTECHNOLOGY
- CDKL5 ensures excitatory synapse stability by reinforcing NGL-1–PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons
- (2012) Sara Ricciardi et al. NATURE CELL BIOLOGY
- Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses
- (2012) Yichen Shi et al. NATURE NEUROSCIENCE
- Primary Cultures of Astrocytes: Their Value in Understanding Astrocytes in Health and Disease
- (2012) Sofie C. Lange et al. NEUROCHEMICAL RESEARCH
- Animal Models of Neurological Disorders
- (2012) Marie-Francoise Chesselet et al. Neurotherapeutics
- Inhibition of Apoptosis Blocks Human Motor Neuron Cell Death in a Stem Cell Model of Spinal Muscular Atrophy
- (2012) Dhruv Sareen et al. PLoS One
- Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability
- (2012) B. Bilican et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Induced pluripotent stem cell model recapitulates pathologic hallmarks of Gaucher disease
- (2012) L. M. Panicker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modeling human cortical development in vitro using induced pluripotent stem cells
- (2012) J. Mariani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Purinergic signaling in human pluripotent stem cells is regulated by the housekeeping gene encoding hypoxanthine guanine phosphoribosyltransferase
- (2012) L. Mastrangelo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genetic Correction of Human Induced Pluripotent Stem Cells from Patients with Spinal Muscular Atrophy
- (2012) S. Corti et al. Science Translational Medicine
- A Human Stem Cell Model of Early Alzheimer's Disease Pathology in Down Syndrome
- (2012) Y. Shi et al. Science Translational Medicine
- Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells
- (2012) N. Egawa et al. Science Translational Medicine
- An Efficient Nonviral Method to Generate Integration-Free Human-Induced Pluripotent Stem Cells from Cord Blood and Peripheral Blood Cells
- (2012) Keisuke Okita et al. STEM CELLS
- Generation of Regionally Specified Neural Progenitors and Functional Neurons from Human Embryonic Stem Cells under Defined Conditions
- (2012) Agnete Kirkeby et al. Cell Reports
- Induced Pluripotent Stem Cells from Ataxia-Telangiectasia Recapitulate the Cellular Phenotype
- (2012) Sam Nayler et al. Stem Cells Translational Medicine
- Induced pluripotent stem cell models from X-linked adrenoleukodystrophy patients
- (2011) Jiho Jang et al. ANNALS OF NEUROLOGY
- When orthologs diverge between human and mouse
- (2011) W. H. Gharib et al. BRIEFINGS IN BIOINFORMATICS
- LRRK2 Mutant iPSC-Derived DA Neurons Demonstrate Increased Susceptibility to Oxidative Stress
- (2011) Ha Nam Nguyen et al. Cell Stem Cell
- Extracellular matrix functions during neuronal migration and lamination in the mammalian central nervous system
- (2011) Santos J. Franco et al. Developmental Neurobiology
- iPS cells to model CDKL5-related disorders
- (2011) Mariangela Amenduni et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Organotypic vibrosections: Novel whole sagittal brain cultures
- (2011) Celine Ullrich et al. JOURNAL OF NEUROSCIENCE METHODS
- Self-formation of functional adenohypophysis in three-dimensional culture
- (2011) Hidetaka Suga et al. NATURE
- Self-organizing optic-cup morphogenesis in three-dimensional culture
- (2011) Mototsugu Eiraku et al. NATURE
- Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome
- (2011) Sergiu P Paşca et al. NATURE MEDICINE
- Development of a Method for the Purification and Culture of Rodent Astrocytes
- (2011) Lynette C. Foo et al. NEURON
- Regional Differentiation of Retinoic Acid-Induced Human Pluripotent Embryonic Carcinoma Stem Cell Neurons
- (2011) Dennis E. Coyle et al. PLoS One
- Isogenic Pairs of Wild Type and Mutant Induced Pluripotent Stem Cell (iPSC) Lines from Rett Syndrome Patients as In Vitro Disease Model
- (2011) Gene Ananiev et al. PLoS One
- Neuronal maturation defect in induced pluripotent stem cells from patients with Rett syndrome
- (2011) K.-Y. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functionally defined substates within the human embryonic stem cell compartment
- (2011) Peter D. Tonge et al. Stem Cell Research
- hESC derived neuro-epithelial rosettes recapitulate early mammalian neurulation events; an in vitro model
- (2011) Carol Lynn Curchoe et al. Stem Cell Research
- Brief Report: Phenotypic Rescue of Induced Pluripotent Stem Cell-Derived Motoneurons of a Spinal Muscular Atrophy Patient
- (2011) Tammy Chang et al. STEM CELLS
- Differentiation Efficiency of Induced Pluripotent Stem Cells Depends on the Number of Reprogramming Factors
- (2011) Matthias Löhle et al. STEM CELLS
- Pluripotent Stem Cells for the Study of CNS Development
- (2011) Timothy J. Petros et al. Frontiers in Molecular Neuroscience
- A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells
- (2010) Maria C.N. Marchetto et al. CELL
- Differential Modeling of Fragile X Syndrome by Human Embryonic Stem Cells and Induced Pluripotent Stem Cells
- (2010) Achia Urbach et al. Cell Stem Cell
- Growth factor delivery-based tissue engineering: general approaches and a review of recent developments
- (2010) K. Lee et al. Journal of the Royal Society Interface
- Developmental genetics of vertebrate glial–cell specification
- (2010) David H. Rowitch et al. NATURE
- L1 retrotransposition in neurons is modulated by MeCP2
- (2010) Alysson R. Muotri et al. NATURE
- Direct conversion of fibroblasts to functional neurons by defined factors
- (2010) Thomas Vierbuchen et al. NATURE
- Neurogenic radial glia in the outer subventricular zone of human neocortex
- (2010) David V. Hansen et al. NATURE
- OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling
- (2010) Simone A Fietz et al. NATURE NEUROSCIENCE
- Neural stem cell systems: physiological players or in vitro entities?
- (2010) Luciano Conti et al. NATURE REVIEWS NEUROSCIENCE
- The Birth and Evolution of Neuroscience Through Cadaveric Dissection
- (2010) Karam Moon et al. NEUROSURGERY
- Induced pluripotent stem cell models of the genomic imprinting disorders Angelman and Prader–Willi syndromes
- (2010) Stormy J. Chamberlain et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dynamic transcriptomes during neural differentiation of human embryonic stem cells revealed by short, long, and paired-end sequencing
- (2010) J. Q. Wu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Matrigel: A complex protein mixture required for optimal growth of cell culture
- (2010) Chris S. Hughes et al. PROTEOMICS
- Generation of Induced Pluripotent Stem Cell Lines from Friedreich Ataxia Patients
- (2010) Jun Liu et al. Stem Cell Reviews and Reports
- Hydrogels as extracellular matrix mimics for 3D cell culture
- (2009) Mark W. Tibbitt et al. BIOTECHNOLOGY AND BIOENGINEERING
- Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors
- (2009) Frank Soldner et al. CELL
- Retinoic Acid from the Meninges Regulates Cortical Neuron Generation
- (2009) Julie A. Siegenthaler et al. CELL
- Neurovascular Congruence during Cerebral Cortical Development
- (2009) Daniel Stubbs et al. CEREBRAL CORTEX
- The human brain in numbers: a linearly scaled-up primate brain
- (2009) Suzana Herculano-Houzel Frontiers in Human Neuroscience
- Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs
- (2009) Gabsang Lee et al. NATURE
- Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
- (2009) Stuart M Chambers et al. NATURE BIOTECHNOLOGY
- Cell-Extracellular Matrix Interactions Regulate Neural Differentiation of Human Embryonic Stem Cells
- (2008) Wu Ma et al. BMC DEVELOPMENTAL BIOLOGY
- Laminin enhances the growth of human neural stem cells in defined culture media
- (2008) Peter E Hall et al. BMC NEUROSCIENCE
- Stem Cells, the Molecular Circuitry of Pluripotency and Nuclear Reprogramming
- (2008) Rudolf Jaenisch et al. CELL
- Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals
- (2008) Mototsugu Eiraku et al. Cell Stem Cell
- Differentiation of neural lineage cells from human pluripotent stem cells
- (2008) P SCHWARTZ et al. METHODS
- Long-term tripotent differentiation capacity of human neural stem (NS) cells in adherent culture
- (2008) Yirui Sun et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Induced pluripotent stem cells from a spinal muscular atrophy patient
- (2008) Allison D. Ebert et al. NATURE
- An intrinsic mechanism of corticogenesis from embryonic stem cells
- (2008) Nicolas Gaspard et al. NATURE
- Thoughts on limitations of animal models
- (2008) Thomas Hartung PARKINSONISM & RELATED DISORDERS
- Reproducible, Ultra High-Throughput Formation of Multicellular Organization from Single Cell Suspension-Derived Human Embryonic Stem Cell Aggregates
- (2008) Mark D. Ungrin et al. PLoS One
- Minimization of exogenous signals in ES cell culture induces rostral hypothalamic differentiation
- (2008) T. Wataya et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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