Brain slice on a chip: opportunities and challenges of applying microfluidic technology to intact tissues

Islet Preconditioning via Multimodal Microfluidic Modulation of Intermittent Hypoxia

(2012) Joe F. Lo et al.   ANALYTICAL CHEMISTRY

Microfluidic 3D bone tissue model for high-throughput evaluation of wound-healing and infection-preventing biomaterials

(2011) Joung-Hyun Lee et al.   BIOMATERIALS

Exploitation of physical and chemical constraints for three-dimensional microtissue construction in microfluidics

(2011) Deepak Choudhury et al.   Biomicrofluidics

An in vitro spinal cord slice preparation for recording from lumbar motoneurons of the adult mouse

(2011) Pratip Mitra et al.   JOURNAL OF NEUROPHYSIOLOGY

Design of hydrodynamically confined microfluidics: controlling flow envelope and pressure

(2011) Kevin V. Christ et al.   LAB ON A CHIP

Development and characterization of a microfluidic chamber incorporating fluid ports with active suction for localized chemical stimulation of brain slices

(2011) Yujie Tanye Tang et al.   LAB ON A CHIP

Optogenetics in Neural Systems

(2011) Ofer Yizhar et al.   NEURON

Roller Coaster Scanning reveals spontaneous triggering of dendritic spikes in CA1 interneurons

(2011) Gergely Katona et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microfluidic quadrupole and floating concentration gradient

(2011) Mohammad A. Qasaimeh et al.   Nature Communications

A microfluidic device for tissue biopsy culture and interrogation

(2010) Abigail Webster et al.   Analytical Methods

Multiphysics simulation of a microfluidic perfusion chamber for brain slice physiology

(2010) Hector H. Caicedo et al.   BIOMEDICAL MICRODEVICES

Measurement of single-cell adhesion strength using a microfluidic assay

(2010) Kevin V. Christ et al.   BIOMEDICAL MICRODEVICES

A brain slice bath for physiology and compound microscopy, with dual-sided perifusion

(2010) P.M. HEYWARD   JOURNAL OF MICROSCOPY

A microfluidic brain slice perfusion chamber for multisite recording using penetrating electrodes

(2010) Alexander J. Blake et al.   JOURNAL OF NEUROSCIENCE METHODS

A novel method for inducing focal ischemia in vitro

(2010) Marc J.P. Richard et al.   JOURNAL OF NEUROSCIENCE METHODS

The membrane chamber: A new type of in vitro recording chamber

(2010) M.R.H. Hill et al.   JOURNAL OF NEUROSCIENCE METHODS

Building and manipulating neural pathways with microfluidics

(2010) Yevgeny Berdichevsky et al.   LAB ON A CHIP

Precise control over the oxygen conditions within the Boyden chamber using a microfabricated insert

(2010) Shawn C. Oppegard et al.   LAB ON A CHIP

Microfluidic perfusion system for maintaining viable heart tissue with real-time electrochemical monitoring of reactive oxygen species

(2010) Lih-Tyng Cheah et al.   LAB ON A CHIP

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Application of microfluidic technology to pancreatic islet research: first decade of endeavor

(2010) Yong Wang et al.   Bioanalysis

A microfluidic wound-healing assay for quantifying endothelial cell migration

(2009) Andries D. van der Meer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Time-resolved lanthanide luminescence for lab-on-a-chip detection of biomarkers on cancerous tissues

(2009) Bo Song et al.   ANALYST

Quantitative Monitoring of Insulin Secretion from Single Islets of Langerhans in Parallel on a Microfluidic Chip

(2009) John F. Dishinger et al.   ANALYTICAL CHEMISTRY

Prevention of air bubble formation in a microfluidic perfusion cell culture system using a microscale bubble trap

(2009) Jong Hwan Sung et al.   BIOMEDICAL MICRODEVICES

Microfluidic biochip for the perifusion of precision-cut rat liver slices for metabolism and toxicology studies

(2009) Paul M. van Midwoud et al.   BIOTECHNOLOGY AND BIOENGINEERING

Maintaining network activity in submerged hippocampal slices: importance of oxygen supply

(2009) Norbert Hájos et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Correlations of Neuronal and Microvascular Densities in Murine Cortex Revealed by Direct Counting and Colocalization of Nuclei and Vessels

(2009) P. S. Tsai et al.   JOURNAL OF NEUROSCIENCE

Culturing thick brain slices: An interstitial 3D microperfusion system for enhanced viability

(2009) Komal Rambani et al.   JOURNAL OF NEUROSCIENCE METHODS

Establishing a physiological environment for visualized in vitro brain slice recordings by increasing oxygen supply and modifying aCSF content

(2009) Norbert Hájos et al.   JOURNAL OF NEUROSCIENCE METHODS

Simultaneous efflux of endogenous D-ser and L-glu from single acute hippocampus slices during oxygen glucose deprivation

(2009) Daniel L. Kirschner et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Chamber and microfluidic probe for microperfusion of organotypic brain slices

(2009) Arthur Queval et al.   LAB ON A CHIP

Cell death and proliferation in acute slices and organotypic cultures of mammalian CNS

(2009) Laura Lossi et al.   PROGRESS IN NEUROBIOLOGY

An In Vitro Protocol for Recording From Spinal Motoneurons of Adult Rats

(2008) Jonathan S. Carp et al.   JOURNAL OF NEUROPHYSIOLOGY

Gamma Oscillations and Spontaneous Network Activity in the Hippocampus Are Highly Sensitive to Decreases in pO2 and Concomitant Changes in Mitochondrial Redox State

(2008) C. Huchzermeyer et al.   JOURNAL OF NEUROSCIENCE

Microfluidics and multielectrode array-compatible organotypic slice culture method

(2008) Yevgeny Berdichevsky et al.   JOURNAL OF NEUROSCIENCE METHODS

Microfluidic add-on for standard electrophysiology chambers

(2008) Javeed Shaikh Mohammed et al.   LAB ON A CHIP

Microfluidic device for multimodal characterization of pancreatic islets

(2008) Javeed Shaikh Mohammed et al.   LAB ON A CHIP

Holographic photolysis of caged neurotransmitters

(2008) Christoph Lutz et al.   NATURE METHODS