Developments in 3D neural cell culture models: the future of neurotherapeutics testing?

Cancer cells mimicin vivospatial-temporal cell-cycle phase distribution and chemosensitivity in 3-dimensional Gelfoam® histoculture but not 2-dimensional culture as visualized with real-time FUCCI imaging

(2015) Shuya Yano et al.   CELL CYCLE

A 3D human neural cell culture system for modeling Alzheimer's disease

(2015) Young Hye Kim et al.   Nature Protocols

Neuronal-glial populations form functional networks in a biocompatible 3D scaffold

(2015) Imogen Smith et al.   NEUROSCIENCE LETTERS

Transplantation of human embryonic stem cell-derived retinal tissue in two primate models of retinal degeneration

(2015) Hiroshi Shirai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human pluripotent stem cell-derived neural constructs for predicting neural toxicity

(2015) Michael P. Schwartz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-Dimensional Neural Spheroid Culture: AnIn VitroModel for Cortical Studies

(2015) Yu-Ting L. Dingle et al.   TISSUE ENGINEERING PART C-METHODS

Organotypic vibrosections from whole brain adult Alzheimer mice (overexpressing amyloid-precursor-protein with the Swedish-Dutch-Iowa mutations) as a model to study clearance of beta-amyloid plaques

(2015) Christian Humpel   Frontiers in Aging Neuroscience

Neural differentiation of pluripotent cells in 3D alginate-based cultures

(2014) Angela Bozza et al.   BIOMATERIALS

An organotypic brain slice preparation from adult patients with temporal lobe epilepsy

(2014) Emmanuel Eugène et al.   JOURNAL OF NEUROSCIENCE METHODS

Lab-on-a-chip technologies for stem cell analysis

(2014) Peter Ertl et al.   TRENDS IN BIOTECHNOLOGY

Size-controllable networked neurospheres as a 3D neuronal tissue model for Alzheimer's disease studies

(2013) Yoon Jung Choi et al.   BIOMATERIALS

The role of hair follicle nestin-expressing stem cells during whisker sensory-nerve growth in long-term 3D culture

(2013) Sumiyuki Mii et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Nestin-Expressing Stem Cells Promote Nerve Growth in Long-Term 3-Dimensional Gelfoam®-Supported Histoculture

(2013) Sumiyuki Mii et al.   PLoS One

Control of three-dimensional substrate stiffness to manipulate mesenchymal stem cell fate toward neuronal or glial lineages

(2012) Goh Jih Her et al.   Acta Biomaterialia

An aligned 3D neuronal-glial co-culture model for peripheral nerve studies

(2012) Muhammad F.B. Daud et al.   BIOMATERIALS

An organotypic spinal cord slice culture model to quantify neurodegeneration

(2012) Madhumitha Ravikumar et al.   JOURNAL OF NEUROSCIENCE METHODS

Brain slice on a chip: opportunities and challenges of applying microfluidic technology to intact tissues

(2012) Yu Huang et al.   LAB ON A CHIP

ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium

(2012) K.-V. Nguyen-Ngoc et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fabrication and optimization of alginate hydrogel constructs for use in 3D neural cell culture

(2011) J P Frampton et al.   Biomedical Materials

Synergistic interaction between cisplatin and gemcitabine in neuroblastoma cell lines and multicellular tumor spheroids

(2011) Odette G. Besançon et al.   CANCER LETTERS

Self-organizing optic-cup morphogenesis in three-dimensional culture

(2011) Mototsugu Eiraku et al.   NATURE

Matrigel: A complex protein mixture required for optimal growth of cell culture

(2010) Chris S. Hughes et al.   PROTEOMICS

Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals

(2008) Mototsugu Eiraku et al.   Cell Stem Cell