Considering aspects of the 3Rs principles within experimental animal biology

Reduction in activity by noxious chemical stimulation is ameliorated by immersion in analgesic drugs in zebrafish

(2017) Javier Lopez-Luna et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Practice makes perfect: Performance optimisation in ‘arboreal’ parkour athletes illuminates the evolutionary ecology of great ape anatomy

(2017) Lewis G. Halsey et al.   JOURNAL OF HUMAN EVOLUTION

Pharmaceutical Metabolism in Fish: Using a 3-D Hepatic In Vitro Model to Assess Clearance

(2017) Matthew G. Baron et al.   PLoS One

Does environmental enrichment promote recovery from stress in rainbow trout?

(2016) Kieran C. Pounder et al.   APPLIED ANIMAL BEHAVIOUR SCIENCE

Impact of tank background on the welfare of the African clawed frog, Xenopus laevis (Daudin)

(2016) Andrew M. Holmes et al.   APPLIED ANIMAL BEHAVIOUR SCIENCE

The influence of heart developmental anatomy on cardiotoxicity-based adverse outcome pathways in fish

(2016) John P. Incardona et al.   AQUATIC TOXICOLOGY

A sensitive biomarker for the detection of aquatic contamination based on behavioral assays using zebrafish larvae

(2016) Leonie K. Nüßer et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Alternative approaches to vertebrate ecotoxicity tests in the 21st century: A review of developments over the last 2 decades and current status

(2016) Adam Lillicrap et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Adverse Effects of Ball-Chain Radio-Collars on Female Mantled Howlers (Alouatta palliata) in Panama

(2016) Mariah E. Hopkins et al.   INTERNATIONAL JOURNAL OF PRIMATOLOGY

Implementing the 3Rs: improving experimental approaches in animal biology

(2016) Kathryn Knight   JOURNAL OF EXPERIMENTAL BIOLOGY

Go forth and replicate!

(2016)   NATURE

1,500 scientists lift the lid on reproducibility

(2016) Monya Baker   NATURE

Procedures for the reconstruction, primary culture and experimental use of rainbow trout gill epithelia

(2016) Sabine Schnell et al.   Nature Protocols

The influence of complex and threatening environments in early life on brain size and behaviour

(2016) C. DePasquale et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

How Adverse Outcome Pathways Can Aid the Development and Use of Computational Prediction Models for Regulatory Toxicology

(2016) Clemens Wittwehr et al.   TOXICOLOGICAL SCIENCES

A two-neuron system for adaptive goal-directed decision-making in Lymnaea

(2016) Michael Crossley et al.   Nature Communications

Drug Discovery via Human-Derived Stem Cell Organoids

(2016) Fangkun Liu et al.   Frontiers in Pharmacology

Effects of surgically implanted tags and translocation on the movements of common bream Abramis brama (L.)

(2015) Chris J. Gardner et al.   FISHERIES RESEARCH

Pain in aquatic animals

(2015) L. U. Sneddon   JOURNAL OF EXPERIMENTAL BIOLOGY

The fickle P value generates irreproducible results

(2015) Lewis G Halsey et al.   NATURE METHODS

Estimating the reproducibility of psychological science

(2015)   SCIENCE

Promoting an open research culture

(2015) B. A. Nosek et al.   SCIENCE

Meta-research: Evaluation and Improvement of Research Methods and Practices

(2015) John P. A. Ioannidis et al.   PLOS BIOLOGY

The Economics of Reproducibility in Preclinical Research

(2015) Leonard P. Freedman et al.   PLOS BIOLOGY

Functional xenobiotic metabolism and efflux transporters in trout hepatocyte spheroid cultures

(2015) Chibuzor Uchea et al.   Toxicology Research

Advancing the 3Rs in regulatory ecotoxicology: A pragmatic cross-sector approach

(2015) Natalie Burden et al.   Integrated Environmental Assessment and Management

Toxicology across scales: Cell population growth in vitro predicts reduced fish growth

(2015) J. Stadnicka-Michalak et al.   Science Advances

Defining and assessing animal pain

(2014) Lynne U. Sneddon et al.   ANIMAL BEHAVIOUR

Pvalues, hypothesis testing, and model selection: it's déjà vu all over again1

(2014) Aaron M. Ellison et al.   ECOLOGY

Comment on Murtaugh

(2014) Michael Lavine   ECOLOGY

Gill cell culture systems as models for aquatic environmental monitoring

(2014) N. R. Bury et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

What do zebrafish want? Impact of social grouping, dominance and gender on preference for enrichment

(2014) Paul Schroeder et al.   LABORATORY ANIMALS

Scientific method: Statistical errors

(2014) Regina Nuzzo   NATURE

High retraction rates raise eyebrows

(2014) Chris Woolston   NATURE

Olfactory exposure to males, including men, causes stress and related analgesia in rodents

(2014) Robert E Sorge et al.   NATURE METHODS

Development of the Horse Grimace Scale (HGS) as a Pain Assessment Tool in Horses Undergoing Routine Castration

(2014) Emanuela Dalla Costa et al.   PLoS One

Extensive review of fish embryo acute toxicities for the prediction of GHS acute systemic toxicity categories

(2014) Stefan Scholz et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

OECD validation study to assess intra- and inter-laboratory reproducibility of the zebrafish embryo toxicity test for acute aquatic toxicity testing

(2014) François Busquet et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Journals unite for reproducibility

(2014) M. McNutt   SCIENCE

Cellular and molecular mechanisms of immunomodulation in the brain through environmental enrichment

(2014) Gaurav Singhal et al.   Frontiers in Cellular Neuroscience

An investigation of the false discovery rate and the misinterpretation of p-values

(2014) D. Colquhoun   Royal Society Open Science

Non-invasive molecular imaging for preclinical cancer therapeutic development

(2013) AC O'Farrell et al.   BRITISH JOURNAL OF PHARMACOLOGY

TOWARDS IMPROVED MODELS FOR PREDICTING BIOCONCENTRATION OF WELL-METABOLIZED COMPOUNDS BY RAINBOW TROUT USING MEASURED RATES OF IN VITRO INTRINSIC CLEARANCE

(2013) John W. Nichols et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Investigating Alternatives to the fish early-life stage test: A strategy for discovering and annotating adverse outcome pathways for early fish development

(2013) Daniel Villeneuve et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Guidelines and Ethical Considerations for Housing and Management of Psittacine Birds Used in Research

(2013) I. D. Kalmar et al.   ILAR JOURNAL

Environmentally relevant stressors alter memory formation in the pond snail Lymnaea

(2013) K. Lukowiak et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Power failure: why small sample size undermines the reliability of neuroscience

(2013) Katherine S. Button et al.   NATURE REVIEWS NEUROSCIENCE

High Impact = High Statistical Standards? Not Necessarily So

(2013) Patrizio E. Tressoldi et al.   PLoS One

A Survey on Data Reproducibility in Cancer Research Provides Insights into Our Limited Ability to Translate Findings from the Laboratory to the Clinic

(2013) Aaron Mobley et al.   PLoS One

Systematic Review of the Empirical Evidence of Study Publication Bias and Outcome Reporting Bias — An Updated Review

(2013) Kerry Dwan et al.   PLoS One

Glucocorticoid Receptor, but Not Mineralocorticoid Receptor, Mediates Cortisol Regulation of Epidermal Ionocyte Development and Ion Transport in Zebrafish (Danio Rerio)

(2013) Shelly Abad Cruz et al.   PLoS One

P-Value Precision and Reproducibility

(2012) Dennis D. Boos et al.   AMERICAN STATISTICIAN

Towards a more representative in vitro method for fish ecotoxicology: morphological and biochemical characterisation of three-dimensional spheroidal hepatocytes

(2012) Matthew G. Baron et al.   ECOTOXICOLOGY

Predicting Fish Acute Toxicity Using a Fish Gill Cell Line-Based Toxicity Assay

(2012) Katrin Tanneberger et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Evaluation of EMLA Cream for Preventing Pain during Tattooing of Rabbits: Changes in Physiological, Behavioural and Facial Expression Responses

(2012) Stephanie C. J. Keating et al.   PLoS One

The Rat Grimace Scale: A Partially Automated Method for Quantifying Pain in the Laboratory Rat via Facial Expressions

(2011) Susana G Sotocina et al.   Molecular Pain

Zebrafish embryos as an alternative to animal experiments—A commentary on the definition of the onset of protected life stages in animal welfare regulations

(2011) Uwe Strähle et al.   REPRODUCTIVE TOXICOLOGY

Power rangers: no improvement in the statistical power of analyses published in Animal Behaviour

(2010) Daniel R. Smith et al.   ANIMAL BEHAVIOUR

Dechorionation as a tool to improve the fish embryo toxicity test (FET) with the zebrafish (Danio rerio)

(2010) Kirsten Henn et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Factors Affecting the Apparent Efficacy and Safety of Tissue Plasminogen Activator in Thrombotic Occlusion Models of Stroke: Systematic Review and Meta-Analysis

(2010) Emily S Sena et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Taming anxiety in laboratory mice

(2010) Jane L Hurst et al.   NATURE METHODS

Coding of facial expressions of pain in the laboratory mouse

(2010) Dale J Langford et al.   NATURE METHODS

Development of a flow-through system for the fish embryo toxicity test (FET) with the zebrafish (Danio rerio)

(2009) E. Lammer et al.   TOXICOLOGY IN VITRO

Reprint: Good Laboratory Practice: Preventing Introduction of Bias at the Bench

(2008) Malcolm R Macleod et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Sample Size Planning for Statistical Power and Accuracy in Parameter Estimation

(2007) Scott E. Maxwell et al.   Annual Review of Psychology

Approach for extrapolating in vitro metabolism data to refine bioconcentration factor estimates

(2007) Christina E. Cowan-Ellsberry et al.   CHEMOSPHERE